ENSG00000135597

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258062 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding protein_coding 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 3.861975 2.2913795 4.1350042 1.4306874 1.4810554 0.84887462 0.08862500 0.052250 0.08245 0.030200 0.82554683 0.02135494 FALSE  
ENST00000367663 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding protein_coding 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 13.725356 12.9719832 12.5494757 0.6078333 1.3262044 -0.04773455 0.30524167 0.274950 0.23905 -0.035900 0.84012718 0.02135494 FALSE  
ENST00000478483 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding protein_coding 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 15.404105 17.3174411 21.7181333 2.3580070 1.2293666 0.32650562 0.32001667 0.372250 0.40960 0.037350 0.88939039 0.02135494 FALSE  
ENST00000484164 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding retained_intron 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 2.269824 3.9223012 0.4024964 0.7393692 0.4024964 -3.25292029 0.05009167 0.082525 0.00680 -0.075725 0.02135494 0.02135494 TRUE  
ENST00000529597 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding protein_coding 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 1.774595 0.8307269 4.4930586 0.4850722 2.5948296 2.42119612 0.03048333 0.016300 0.07515 0.058850 0.89757731 0.02135494 FALSE  
ENST00000530255 ENSG00000135597 No_inf pgKDN_inf REPS1 protein_coding protein_coding 46.92472 47.19351 53.9104 2.223368 3.535547 0.191937 5.558318 5.4401069 6.6937638 3.1916713 4.1486039 0.29868678 0.11020000 0.107700 0.11165 0.003950 1.00000000 0.02135494 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135597 E001 0.0000000       6 138903493 138904016 524 -      
ENSG00000135597 E002 0.0000000       6 138904017 138904029 13 -      
ENSG00000135597 E003 0.3726284 0.0166009567 0.557439123   6 138904030 138904099 70 - 0.093 0.177 1.072
ENSG00000135597 E004 9.1225128 0.1104934086 0.426445670 0.705043411 6 138904100 138904859 760 - 1.061 0.943 -0.433
ENSG00000135597 E005 1.5672346 0.0085486171 0.189593730 0.468352872 6 138904860 138904860 1 - 0.498 0.302 -1.098
ENSG00000135597 E006 2.1729597 0.0079960423 0.188399173 0.466748782 6 138904861 138904865 5 - 0.587 0.399 -0.928
ENSG00000135597 E007 2.1805765 0.0338085006 0.431913540 0.709492071 6 138904866 138904866 1 - 0.559 0.440 -0.580
ENSG00000135597 E008 2.5435460 0.0286152467 0.359085864 0.648529995 6 138904867 138904869 3 - 0.613 0.478 -0.628
ENSG00000135597 E009 6.0932915 0.0023248120 0.492015846 0.754345972 6 138904870 138904891 22 - 0.886 0.814 -0.276
ENSG00000135597 E010 45.9765898 0.0057018627 0.355404365 0.645182734 6 138904892 138905132 241 - 1.645 1.696 0.172
ENSG00000135597 E011 0.0000000       6 138907372 138907494 123 -      
ENSG00000135597 E012 20.8001844 0.0023626053 0.864948208 0.953321594 6 138907495 138907534 40 - 1.343 1.334 -0.030
ENSG00000135597 E013 25.2081832 0.0006037022 0.916780638 0.973849013 6 138907535 138907600 66 - 1.420 1.417 -0.012
ENSG00000135597 E014 46.0869619 0.0003558380 0.647313194 0.850935698 6 138908668 138908794 127 - 1.682 1.664 -0.058
ENSG00000135597 E015 19.9571861 0.0007010621 0.720141171 0.887266565 6 138908795 138908816 22 - 1.308 1.334 0.090
ENSG00000135597 E016 0.0000000       6 138908817 138908912 96 -      
ENSG00000135597 E017 0.4996734 0.0244345421 0.300781545   6 138910923 138911245 323 - 0.093 0.244 1.657
ENSG00000135597 E018 0.1268540 0.0123060406 0.515545484   6 138911246 138911275 30 - 0.000 0.097 9.880
ENSG00000135597 E019 38.5324255 0.0003888201 0.904128980 0.969140877 6 138911276 138911371 96 - 1.598 1.595 -0.010
ENSG00000135597 E020 0.1272623 0.0123415759 0.515470402   6 138912675 138912764 90 - 0.000 0.097 9.880
ENSG00000135597 E021 34.7069208 0.0004942673 0.409323254 0.691531148 6 138912765 138912865 101 - 1.572 1.533 -0.131
ENSG00000135597 E022 23.9060780 0.0006159605 0.157745129 0.424457483 6 138912866 138912950 85 - 1.436 1.354 -0.283
ENSG00000135597 E023 26.0270712 0.0005272615 0.565859540 0.804445897 6 138914697 138914761 65 - 1.447 1.417 -0.104
ENSG00000135597 E024 1.5069123 0.0087859734 0.013950974 0.099792023 6 138914762 138915187 426 - 0.170 0.545 2.394
ENSG00000135597 E025 38.4602919 0.0012233791 0.046544592 0.211735871 6 138915858 138915976 119 - 1.543 1.643 0.340
ENSG00000135597 E026 2.1328432 0.0068802154 0.004616375 0.046800674 6 138915977 138916214 238 - 0.235 0.655 2.295
ENSG00000135597 E027 21.1600241 0.0007891747 0.049604540 0.219687027 6 138917555 138917624 70 - 1.277 1.404 0.443
ENSG00000135597 E028 6.6703471 0.0027678237 0.040470320 0.195109378 6 138917625 138917627 3 - 0.762 0.979 0.838
ENSG00000135597 E029 0.7616853 0.0202430593 0.008487476 0.071896270 6 138917628 138917646 19 - 0.000 0.399 12.465
ENSG00000135597 E030 26.4266478 0.0007898474 0.058698132 0.242815235 6 138920215 138920301 87 - 1.379 1.489 0.382
ENSG00000135597 E031 18.0619831 0.0240066210 0.308985285 0.602335358 6 138920302 138920316 15 - 1.230 1.324 0.328
ENSG00000135597 E032 18.0654274 0.0303650443 0.308089358 0.601306052 6 138921037 138921063 27 - 1.224 1.329 0.368
ENSG00000135597 E033 24.8609447 0.0081003242 0.734742458 0.894744808 6 138921064 138921124 61 - 1.400 1.425 0.086
ENSG00000135597 E034 7.7934700 0.0017917846 0.285200204 0.578879565 6 138926401 138926478 78 - 0.993 0.891 -0.382
ENSG00000135597 E035 2.4682387 0.0058068286 0.325554402 0.618082175 6 138926479 138926481 3 - 0.464 0.603 0.657
ENSG00000135597 E036 2.1125766 0.0739951350 0.126498477 0.376958331 6 138926482 138929976 3495 - 0.341 0.603 1.335
ENSG00000135597 E037 29.8067913 0.0004973212 0.414323283 0.694619315 6 138929977 138930098 122 - 1.509 1.468 -0.141
ENSG00000135597 E038 0.6259894 0.0146186398 0.158820248 0.425918074 6 138934225 138934288 64 - 0.093 0.302 2.072
ENSG00000135597 E039 0.4991354 0.0152174039 0.298916634   6 138934289 138934326 38 - 0.093 0.244 1.657
ENSG00000135597 E040 27.1261069 0.0118736281 0.370130223 0.658418926 6 138941335 138941489 155 - 1.416 1.479 0.215
ENSG00000135597 E041 14.3811261 0.0032035826 0.299368365 0.592309894 6 138943513 138943576 64 - 1.143 1.226 0.294
ENSG00000135597 E042 23.2661222 0.0006037718 0.875485149 0.957499768 6 138943853 138944015 163 - 1.379 1.391 0.042
ENSG00000135597 E043 13.5780542 0.0010143880 0.808114339 0.929176938 6 138944498 138944560 63 - 1.172 1.155 -0.058
ENSG00000135597 E044 15.3366420 0.0085669626 0.440205778 0.715977393 6 138944561 138944622 62 - 1.179 1.245 0.234
ENSG00000135597 E045 24.9984346 0.0005578862 0.552509226 0.796051614 6 138945219 138945372 154 - 1.396 1.433 0.129
ENSG00000135597 E046 30.4479212 0.0041762338 0.077067717 0.284015732 6 138945501 138945697 197 - 1.546 1.445 -0.346
ENSG00000135597 E047 16.0641685 0.0065202624 0.000106160 0.002492657 6 138947790 138947881 92 - 1.361 1.053 -1.094
ENSG00000135597 E048 9.5502251 0.0076868990 0.003498069 0.038764095 6 138947882 138947913 32 - 1.143 0.862 -1.039
ENSG00000135597 E049 0.3726934 0.0165848216 0.556971905   6 138951042 138951160 119 - 0.093 0.177 1.072
ENSG00000135597 E050 38.3430991 0.0003736044 0.008228222 0.070426526 6 138987530 138988323 794 - 1.652 1.530 -0.418

Help

Please Click HERE to learn more details about the results from DEXseq.