ENSG00000135655

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312635 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding protein_coding 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 5.161399 6.457937 5.6313059 0.5058235 0.4956820 -0.1972765 0.09185833 0.116300 0.092175 -0.024125 0.84563248 0.03066417 FALSE  
ENST00000547317 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding protein_coding_CDS_not_defined 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 1.681238 3.736208 0.4063903 0.6460128 0.4063903 -3.1694227 0.02886667 0.063075 0.006750 -0.056325 0.03066417 0.03066417    
ENST00000549268 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding retained_intron 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 13.662892 12.295642 15.7796578 0.8169277 1.3758114 0.3596600 0.24354167 0.220000 0.257375 0.037375 0.83546823 0.03066417 FALSE  
ENST00000549415 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding protein_coding 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 12.610387 11.016599 13.8263345 0.7374728 0.4607585 0.3274739 0.22576667 0.196050 0.226350 0.030300 0.83709451 0.03066417 FALSE  
ENST00000550632 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding protein_coding_CDS_not_defined 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 12.084080 7.840870 15.9398799 1.6726748 2.3413584 1.0226211 0.21298333 0.134100 0.259650 0.125550 0.29800038 0.03066417 FALSE  
ENST00000618986 ENSG00000135655 No_inf pgKDN_inf USP15 protein_coding miRNA 57.32309 59.71065 61.15483 11.38824 0.8035275 0.03447267 2.917623 8.752870 0.0000000 8.7528701 0.0000000 -9.7752597 0.03133333 0.094000 0.000000 -0.094000 0.89363981 0.03066417    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135655 E001 0.2451451 0.0163480483 9.944060e-01   12 62260338 62260355 18 + 0.095 0.096 0.015
ENSG00000135655 E002 0.2451451 0.0163480483 9.944060e-01   12 62260356 62260358 3 + 0.095 0.096 0.015
ENSG00000135655 E003 0.2451451 0.0163480483 9.944060e-01   12 62260359 62260363 5 + 0.095 0.096 0.015
ENSG00000135655 E004 0.8431822 0.3178740217 3.743223e-01 0.6620301977 12 62260364 62260396 33 + 0.346 0.174 -1.308
ENSG00000135655 E005 0.5980370 0.1880098619 2.371900e-01 0.5261415833 12 62260397 62260398 2 + 0.295 0.096 -1.985
ENSG00000135655 E006 0.9599340 0.1184285449 2.076286e-01 0.4912370708 12 62260399 62260403 5 + 0.391 0.174 -1.570
ENSG00000135655 E007 1.0867880 0.0748112318 3.645434e-01 0.6531819797 12 62260404 62260406 3 + 0.391 0.240 -0.985
ENSG00000135655 E008 1.2054911 0.0171691907 2.132503e-01 0.4984588814 12 62260407 62260407 1 + 0.432 0.240 -1.207
ENSG00000135655 E009 3.4124009 0.0067091630 4.738897e-01 0.7407886620 12 62260408 62260427 20 + 0.690 0.597 -0.400
ENSG00000135655 E010 9.4138905 0.0014851969 7.643344e-01 0.9082891057 12 62260428 62260503 76 + 1.031 1.004 -0.098
ENSG00000135655 E011 0.0000000       12 62278628 62278714 87 +      
ENSG00000135655 E012 16.3976678 0.0023459311 7.731359e-01 0.9126753590 12 62294179 62294306 128 + 1.250 1.230 -0.071
ENSG00000135655 E013 0.1187032 0.0118532474 5.433896e-01   12 62294307 62294640 334 + 0.095 0.000 -11.227
ENSG00000135655 E014 18.7809611 0.0006950884 1.631885e-01 0.4318461427 12 62302790 62302920 131 + 1.341 1.249 -0.324
ENSG00000135655 E015 5.3406141 0.0231352795 1.776004e-02 0.1172474797 12 62302921 62303586 666 + 0.620 0.923 1.221
ENSG00000135655 E016 2.1008268 0.1441869120 2.748008e-01 0.5682496607 12 62304465 62304672 208 + 0.391 0.569 0.890
ENSG00000135655 E017 20.3410104 0.0071800127 3.298702e-05 0.0009358873 12 62304673 62305594 922 + 1.143 1.452 1.082
ENSG00000135655 E018 3.9729828 0.0036365712 3.173829e-02 0.1683170727 12 62305595 62305738 144 + 0.536 0.807 1.152
ENSG00000135655 E019 6.7706040 0.0043350868 3.389174e-01 0.6305578932 12 62305739 62306058 320 + 0.835 0.936 0.384
ENSG00000135655 E020 0.0000000       12 62312286 62312309 24 +      
ENSG00000135655 E021 25.6708699 0.0005197233 1.250930e-02 0.0928666891 12 62314790 62314916 127 + 1.494 1.350 -0.496
ENSG00000135655 E022 0.0000000       12 62314917 62315073 157 +      
ENSG00000135655 E023 0.0000000       12 62321461 62321463 3 +      
ENSG00000135655 E024 26.8209170 0.0005936494 4.238821e-04 0.0076742731 12 62321464 62321609 146 + 1.536 1.336 -0.691
ENSG00000135655 E025 14.4871380 0.0010101956 9.145202e-02 0.3140410434 12 62325872 62325933 62 + 1.250 1.124 -0.450
ENSG00000135655 E026 0.3807797 0.0404346213 1.044538e-01   12 62327661 62327781 121 + 0.000 0.240 11.734
ENSG00000135655 E027 0.4892828 0.0718459577 1.000000e+00   12 62328293 62328405 113 + 0.172 0.174 0.015
ENSG00000135655 E028 45.3768961 0.0003464629 3.269464e-04 0.0062375412 12 62335166 62336690 1525 + 1.577 1.736 0.538
ENSG00000135655 E029 0.4992651 0.4449689657 5.435551e-01   12 62342689 62342826 138 + 0.095 0.240 1.599
ENSG00000135655 E030 12.2830180 0.0012032173 4.157223e-02 0.1981929276 12 62349221 62349307 87 + 1.200 1.035 -0.594
ENSG00000135655 E031 0.0000000       12 62355011 62355074 64 +      
ENSG00000135655 E032 21.8507541 0.0099827847 2.499950e-01 0.5409337662 12 62355331 62355427 97 + 1.400 1.316 -0.293
ENSG00000135655 E033 14.5544600 0.0159942746 6.996090e-01 0.8775975819 12 62355428 62355475 48 + 1.207 1.177 -0.107
ENSG00000135655 E034 4.2376394 0.0044639872 5.401465e-03 0.0523490812 12 62374390 62374535 146 + 0.504 0.854 1.489
ENSG00000135655 E035 26.7574454 0.0039105182 4.432635e-01 0.7182593423 12 62381490 62381663 174 + 1.466 1.421 -0.157
ENSG00000135655 E036 23.3286421 0.0185605690 4.865501e-01 0.7501242050 12 62383840 62383998 159 + 1.412 1.360 -0.182
ENSG00000135655 E037 0.2435110 0.0163621512 9.948970e-01   12 62383999 62384077 79 + 0.095 0.096 0.015
ENSG00000135655 E038 40.1520917 0.0005216821 9.340703e-01 0.9810236738 12 62384078 62384302 225 + 1.612 1.616 0.015
ENSG00000135655 E039 18.3267103 0.0017374980 4.559800e-01 0.7283957503 12 62389431 62389514 84 + 1.311 1.261 -0.178
ENSG00000135655 E040 18.4727724 0.0207558445 7.264034e-01 0.8904754328 12 62389605 62389699 95 + 1.306 1.272 -0.120
ENSG00000135655 E041 32.4062307 0.0004396492 5.440960e-01 0.7906793178 12 62389797 62389988 192 + 1.539 1.508 -0.105
ENSG00000135655 E042 20.8697941 0.0007434414 2.767852e-01 0.5702332155 12 62390864 62390979 116 + 1.374 1.305 -0.239
ENSG00000135655 E043 53.1220666 0.0002831866 6.954368e-01 0.8756782188 12 62391157 62391429 273 + 1.741 1.726 -0.052
ENSG00000135655 E044 23.7446721 0.0006375164 8.239754e-01 0.9361565279 12 62391816 62391886 71 + 1.400 1.387 -0.045
ENSG00000135655 E045 25.1122259 0.0020676957 3.528335e-02 0.1798211577 12 62392272 62392361 90 + 1.346 1.474 0.442
ENSG00000135655 E046 14.6392745 0.0010737031 1.560562e-01 0.4222090315 12 62392362 62392387 26 + 1.136 1.243 0.381
ENSG00000135655 E047 14.1102348 0.0009805737 6.077176e-01 0.8291532988 12 62393053 62393074 22 + 1.158 1.198 0.140
ENSG00000135655 E048 30.5700216 0.0004660428 2.471738e-01 0.5377613781 12 62393075 62393202 128 + 1.466 1.528 0.212
ENSG00000135655 E049 0.0000000       12 62396284 62396294 11 +      
ENSG00000135655 E050 28.7512648 0.0004778649 7.962906e-01 0.9228203556 12 62396295 62396398 104 + 1.480 1.467 -0.046
ENSG00000135655 E051 0.0000000       12 62401158 62401186 29 +      
ENSG00000135655 E052 23.5037095 0.0005926494 9.362033e-01 0.9817847270 12 62401187 62401275 89 + 1.391 1.387 -0.015
ENSG00000135655 E053 121.5294163 0.0003138612 6.706594e-01 0.8631546411 12 62404193 62416389 12197 + 2.082 2.093 0.038
ENSG00000135655 E054 0.1271363 0.0124536046 5.329674e-01   12 62417098 62417431 334 + 0.000 0.096 10.372

Help

Please Click HERE to learn more details about the results from DEXseq.