ENSG00000135775

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366668 ENSG00000135775 No_inf pgKDN_inf COG2 protein_coding protein_coding 20.29826 18.15066 21.86585 0.8851378 0.6964127 0.2685228 0.9615871 2.130555 0.2989167 2.1305554 0.2989167 -2.7926952 0.0507500 0.117975 0.013100 -0.104875 1.00000000 0.04726126 FALSE TRUE
ENST00000366669 ENSG00000135775 No_inf pgKDN_inf COG2 protein_coding protein_coding 20.29826 18.15066 21.86585 0.8851378 0.6964127 0.2685228 15.4887009 9.945951 18.7258939 1.6331048 0.8702248 0.9121738 0.7555417 0.554025 0.857050 0.303025 0.04726126 0.04726126 FALSE TRUE
ENST00000482012 ENSG00000135775 No_inf pgKDN_inf COG2 protein_coding protein_coding_CDS_not_defined 20.29826 18.15066 21.86585 0.8851378 0.6964127 0.2685228 0.3604488 1.081346 0.0000000 1.0813464 0.0000000 -6.7699652 0.0176000 0.052800 0.000000 -0.052800 0.83709451 0.04726126 FALSE FALSE
MSTRG.2841.8 ENSG00000135775 No_inf pgKDN_inf COG2 protein_coding   20.29826 18.15066 21.86585 0.8851378 0.6964127 0.2685228 2.2958368 3.870003 1.8844403 0.4799502 0.3582762 -1.0342863 0.1165250 0.211575 0.085625 -0.125950 0.24367285 0.04726126   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135775 E001 0.2373413 0.0158056235 2.937193e-01   1 230642481 230642488 8 + 0.163 0.000 -11.358
ENSG00000135775 E002 1.9466572 0.1126096257 5.796307e-01 8.123114e-01 1 230642489 230642504 16 + 0.517 0.411 -0.539
ENSG00000135775 E003 2.5632971 0.0527466203 7.756943e-01 9.138154e-01 1 230642505 230642520 16 + 0.573 0.526 -0.216
ENSG00000135775 E004 3.5251615 0.0057730153 3.581185e-01 6.476466e-01 1 230642521 230642566 46 + 0.709 0.589 -0.512
ENSG00000135775 E005 8.1509079 0.0019055463 3.065936e-01 5.997976e-01 1 230642567 230642678 112 + 1.006 0.907 -0.368
ENSG00000135775 E006 0.1268540 0.0123850421 4.675888e-01   1 230642811 230643040 230 + 0.000 0.101 10.651
ENSG00000135775 E007 12.9869879 0.0011115014 8.440954e-02 3.000492e-01 1 230659464 230659625 162 + 1.206 1.070 -0.488
ENSG00000135775 E008 6.5912622 0.0023581342 9.742469e-01 9.953877e-01 1 230660758 230660823 66 + 0.882 0.878 -0.015
ENSG00000135775 E009 0.0000000       1 230660824 230660873 50 +      
ENSG00000135775 E010 0.0000000       1 230661325 230661557 233 +      
ENSG00000135775 E011 8.7919633 0.0016259011 9.105949e-01 9.716700e-01 1 230663141 230663221 81 + 0.996 0.985 -0.042
ENSG00000135775 E012 14.2665203 0.0012774057 5.250746e-01 7.779229e-01 1 230664484 230664587 104 + 1.206 1.158 -0.173
ENSG00000135775 E013 13.1394063 0.0068566321 1.889375e-01 4.675334e-01 1 230668676 230668784 109 + 1.200 1.089 -0.397
ENSG00000135775 E014 0.5906140 0.0144843400 2.988092e-02 1.626070e-01 1 230668927 230669122 196 + 0.331 0.000 -12.680
ENSG00000135775 E015 17.3496209 0.0008537557 2.038862e-02 1.284626e-01 1 230669356 230669535 180 + 1.334 1.173 -0.565
ENSG00000135775 E016 13.3444530 0.0089076942 2.916710e-03 3.380826e-02 1 230669536 230671515 1980 + 1.016 1.269 0.907
ENSG00000135775 E017 18.0946482 0.0008089753 5.728266e-02 2.392537e-01 1 230671516 230671640 125 + 1.338 1.210 -0.451
ENSG00000135775 E018 14.5894499 0.0251619573 3.091840e-01 6.025485e-01 1 230674998 230675124 127 + 1.236 1.141 -0.336
ENSG00000135775 E019 17.5867794 0.0008454340 9.965247e-01 1.000000e+00 1 230678913 230679052 140 + 1.269 1.269 -0.002
ENSG00000135775 E020 14.1565162 0.0011546532 2.457568e-07 1.307165e-05 1 230679053 230683428 4376 + 0.943 1.342 1.433
ENSG00000135775 E021 13.7304615 0.0028172449 2.680902e-01 5.615432e-01 1 230683574 230683635 62 + 1.125 1.210 0.302
ENSG00000135775 E022 0.1265070 0.0122706595 4.677599e-01   1 230684323 230684440 118 + 0.000 0.101 10.651
ENSG00000135775 E023 22.7405733 0.0006368843 5.954358e-01 8.220718e-01 1 230685085 230685236 152 + 1.360 1.391 0.106
ENSG00000135775 E024 27.9840376 0.0006360740 8.345484e-01 9.403559e-01 1 230686935 230687132 198 + 1.457 1.467 0.035
ENSG00000135775 E025 0.9881989 0.1589983266 4.390156e-01 7.150462e-01 1 230687990 230688070 81 + 0.227 0.364 0.937
ENSG00000135775 E026 10.1255445 0.0014639008 7.240213e-01 8.891065e-01 1 230688071 230688143 73 + 1.061 1.029 -0.115
ENSG00000135775 E027 3.2402491 0.0047302783 6.417595e-03 5.928855e-02 1 230688144 230688419 276 + 0.415 0.777 1.639
ENSG00000135775 E028 2.6882090 0.0054505910 9.219258e-01 9.757480e-01 1 230688420 230688422 3 + 0.573 0.559 -0.064
ENSG00000135775 E029 15.8928053 0.0008344689 7.819125e-01 9.160998e-01 1 230688423 230688562 140 + 1.218 1.237 0.066
ENSG00000135775 E030 0.0000000       1 230689961 230690013 53 +      
ENSG00000135775 E031 13.6679134 0.0190701067 9.695275e-01 9.937497e-01 1 230690014 230690153 140 + 1.167 1.165 -0.007
ENSG00000135775 E032 0.0000000       1 230690154 230690319 166 +      
ENSG00000135775 E033 0.0000000       1 230691384 230691564 181 +      
ENSG00000135775 E034 0.0000000       1 230691565 230691819 255 +      
ENSG00000135775 E035 0.0000000       1 230693292 230693982 691 +      

Help

Please Click HERE to learn more details about the results from DEXseq.