ENSG00000135924

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336576 ENSG00000135924 No_inf pgKDN_inf DNAJB2 protein_coding protein_coding 22.73598 25.72461 18.31411 1.349073 1.284078 -0.4899663 5.039237 6.394376 3.549154 0.5622405 0.7013964 -0.8475236 0.2238417 0.253750 0.194650 -0.059100 0.834711985 0.001306392 FALSE TRUE
ENST00000392086 ENSG00000135924 No_inf pgKDN_inf DNAJB2 protein_coding protein_coding 22.73598 25.72461 18.31411 1.349073 1.284078 -0.4899663 4.403489 1.332149 10.190468 1.3321488 0.8140672 2.9260187 0.2266417 0.051450 0.555325 0.503875 0.001306392 0.001306392 FALSE TRUE
ENST00000463463 ENSG00000135924 No_inf pgKDN_inf DNAJB2 protein_coding protein_coding_CDS_not_defined 22.73598 25.72461 18.31411 1.349073 1.284078 -0.4899663 2.756921 4.462995 0.000000 2.5874491 0.0000000 -8.8050973 0.1022667 0.162200 0.000000 -0.162200 0.543297411 0.001306392   FALSE
ENST00000472019 ENSG00000135924 No_inf pgKDN_inf DNAJB2 protein_coding retained_intron 22.73598 25.72461 18.31411 1.349073 1.284078 -0.4899663 2.422044 4.669803 0.000000 1.9333555 0.0000000 -8.8703041 0.0866250 0.171100 0.000000 -0.171100 0.037269747 0.001306392   FALSE
MSTRG.17659.1 ENSG00000135924 No_inf pgKDN_inf DNAJB2 protein_coding   22.73598 25.72461 18.31411 1.349073 1.284078 -0.4899663 2.519388 2.157208 0.000000 2.1572080 0.0000000 -7.7596938 0.1135333 0.098525 0.000000 -0.098525 0.913188194 0.001306392 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135924 E001 0.0000000       2 219279342 219279343 2 +      
ENSG00000135924 E002 0.0000000       2 219279344 219279347 4 +      
ENSG00000135924 E003 0.0000000       2 219279348 219279365 18 +      
ENSG00000135924 E004 0.0000000       2 219279366 219279366 1 +      
ENSG00000135924 E005 0.0000000       2 219279367 219279368 2 +      
ENSG00000135924 E006 0.9813697 0.0115461225 0.612574808 0.831515609 2 219279369 219279449 81 + 0.336 0.260 -0.508
ENSG00000135924 E007 1.3241658 0.0097498517 0.035145407 0.179450192 2 219279450 219279464 15 + 0.523 0.208 -1.923
ENSG00000135924 E008 3.1590822 0.0045211420 0.036746224 0.184555688 2 219279465 219279515 51 + 0.754 0.485 -1.186
ENSG00000135924 E009 2.4318288 0.0058859679 0.090490823 0.312408752 2 219279516 219279516 1 + 0.653 0.422 -1.093
ENSG00000135924 E010 2.4318288 0.0058859679 0.090490823 0.312408752 2 219279517 219279518 2 + 0.653 0.422 -1.093
ENSG00000135924 E011 0.6255466 0.1581220026 0.396682760 0.681316094 2 219279519 219279587 69 + 0.111 0.260 1.492
ENSG00000135924 E012 0.8623263 0.1540366191 0.898140042 0.966428287 2 219279588 219279687 100 + 0.273 0.260 -0.093
ENSG00000135924 E013 1.2249755 0.0103425121 0.570000381 0.806819514 2 219279688 219279797 110 + 0.391 0.307 -0.508
ENSG00000135924 E014 7.9759119 0.0017940941 0.275151068 0.568635600 2 219279798 219279898 101 + 1.002 0.902 -0.375
ENSG00000135924 E015 0.2441377 0.0165619742 0.776526600   2 219279899 219279905 7 + 0.111 0.081 -0.508
ENSG00000135924 E016 0.2441377 0.0165619742 0.776526600   2 219279906 219279919 14 + 0.111 0.081 -0.508
ENSG00000135924 E017 0.2441377 0.0165619742 0.776526600   2 219279920 219279975 56 + 0.111 0.081 -0.508
ENSG00000135924 E018 0.0000000       2 219279976 219280059 84 +      
ENSG00000135924 E019 0.2537694 0.0161775286 0.394790432   2 219280060 219280170 111 + 0.000 0.149 10.269
ENSG00000135924 E020 7.9356930 0.0018534090 0.177416745 0.452003943 2 219280578 219280612 35 + 0.853 0.992 0.526
ENSG00000135924 E021 10.5108956 0.0013826147 0.390821928 0.676126567 2 219280613 219280687 75 + 1.002 1.082 0.293
ENSG00000135924 E022 1.6416961 0.0086358171 0.007116038 0.063753556 2 219280688 219280839 152 + 0.111 0.539 3.077
ENSG00000135924 E023 9.8501102 0.0171764994 0.009150532 0.075857642 2 219280840 219281717 878 + 0.835 1.118 1.053
ENSG00000135924 E024 9.6568380 0.0015357150 0.028895079 0.159319162 2 219281718 219281771 54 + 1.123 0.934 -0.691
ENSG00000135924 E025 18.7370513 0.0008377100 0.017548905 0.116246947 2 219281939 219282061 123 + 1.371 1.220 -0.527
ENSG00000135924 E026 2.4406703 0.0055215134 0.211934545 0.496998901 2 219282062 219282478 417 + 0.624 0.454 -0.798
ENSG00000135924 E027 0.9741003 0.0956203027 0.274096980 0.567635484 2 219282479 219282697 219 + 0.391 0.208 -1.246
ENSG00000135924 E028 0.2458395 0.0164196400 0.776741927   2 219282698 219282741 44 + 0.111 0.081 -0.508
ENSG00000135924 E029 0.2537694 0.0161775286 0.394790432   2 219282742 219282836 95 + 0.000 0.149 10.269
ENSG00000135924 E030 18.0443096 0.0007980112 0.138328301 0.395703015 2 219282837 219282929 93 + 1.325 1.231 -0.331
ENSG00000135924 E031 0.6342667 0.0142924036 0.052866126 0.228504698 2 219282930 219283063 134 + 0.000 0.307 11.451
ENSG00000135924 E032 1.6326969 0.0480672346 0.061421216 0.248906142 2 219283064 219283132 69 + 0.200 0.513 1.951
ENSG00000135924 E033 19.1200609 0.0007875021 0.046813813 0.212458446 2 219283133 219283235 103 + 1.365 1.241 -0.434
ENSG00000135924 E034 0.6155403 0.0148643311 0.964552861 0.992514768 2 219283236 219283418 183 + 0.200 0.208 0.077
ENSG00000135924 E035 12.4637293 0.0011320809 0.773897809 0.913055179 2 219283419 219283489 71 + 1.103 1.131 0.101
ENSG00000135924 E036 16.8691711 0.0009301157 0.746348899 0.899672909 2 219284632 219284835 204 + 1.254 1.236 -0.062
ENSG00000135924 E037 12.5700459 0.0010803040 0.005042491 0.049919546 2 219284836 219285262 427 + 0.963 1.204 0.874
ENSG00000135924 E038 25.6056116 0.0006383104 0.000463225 0.008229109 2 219285263 219285776 514 + 1.274 1.488 0.741
ENSG00000135924 E039 3.0187978 0.0411778361 0.005116248 0.050492173 2 219285777 219285800 24 + 0.273 0.725 2.299
ENSG00000135924 E040 8.4480206 0.0017426745 0.084261797 0.299742144 2 219285801 219285986 186 + 0.853 1.027 0.654
ENSG00000135924 E041 19.4604422 0.0007436849 0.715308550 0.885283915 2 219285987 219286265 279 + 1.313 1.294 -0.066
ENSG00000135924 E042 59.5928390 0.0002842956 0.329333351 0.621728430 2 219286266 219286898 633 + 1.790 1.761 -0.100

Help

Please Click HERE to learn more details about the results from DEXseq.