ENSG00000135926

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258412 ENSG00000135926 No_inf pgKDN_inf TMBIM1 protein_coding protein_coding 48.72636 59.23238 42.19525 3.271893 1.965794 -0.4892072 38.80351 41.49745 37.742467 1.718927 1.2569561 -0.1367995 0.81563333 0.7065 0.896300 0.189800 0.002590081 0.002590081 FALSE TRUE
ENST00000492966 ENSG00000135926 No_inf pgKDN_inf TMBIM1 protein_coding retained_intron 48.72636 59.23238 42.19525 3.271893 1.965794 -0.4892072 5.56158 10.36292 2.122039 3.042097 0.7267284 -2.2825164 0.09936667 0.1675 0.048975 -0.118525 0.428274638 0.002590081 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135926 E001 0.1170040 0.0117486505 3.879509e-01   2 218274197 218274200 4 - 0.110 0.000 -9.622
ENSG00000135926 E002 189.1810953 0.0001319738 1.442577e-01 4.043973e-01 2 218274201 218275005 805 - 2.253 2.283 0.100
ENSG00000135926 E003 138.1228212 0.0003953850 7.204915e-01 8.874416e-01 2 218275006 218275431 426 - 2.130 2.139 0.032
ENSG00000135926 E004 50.4226135 0.0004528001 2.919693e-01 5.853712e-01 2 218275432 218275621 190 - 1.729 1.685 -0.149
ENSG00000135926 E005 26.5446012 0.0004922811 3.261889e-01 6.187192e-01 2 218276026 218276079 54 - 1.464 1.409 -0.192
ENSG00000135926 E006 35.3373743 0.0007423008 6.996252e-01 8.775976e-01 2 218277004 218277099 96 - 1.563 1.544 -0.065
ENSG00000135926 E007 0.0000000       2 218277363 218277365 3 -      
ENSG00000135926 E008 36.7195586 0.0004435406 9.648820e-01 9.925984e-01 2 218277366 218277453 88 - 1.567 1.569 0.009
ENSG00000135926 E009 28.3018637 0.0005114468 1.256725e-01 3.758156e-01 2 218277633 218277670 38 - 1.405 1.492 0.301
ENSG00000135926 E010 2.2483949 0.0062249925 7.967211e-02 2.896357e-01 2 218277801 218277934 134 - 0.332 0.594 1.348
ENSG00000135926 E011 23.2475221 0.0027057749 7.219087e-01 8.881589e-01 2 218277935 218277945 11 - 1.390 1.368 -0.076
ENSG00000135926 E012 29.8494458 0.0011809199 3.214592e-01 6.145157e-01 2 218277946 218277974 29 - 1.513 1.459 -0.186
ENSG00000135926 E013 1.2446447 0.0100547907 4.350101e-01 7.119411e-01 2 218277975 218278165 191 - 0.270 0.391 0.763
ENSG00000135926 E014 1.2538069 0.0438163359 1.579038e-01 4.246938e-01 2 218278409 218278478 70 - 0.197 0.427 1.540
ENSG00000135926 E015 0.2543986 0.0161056095 3.726227e-01   2 218278479 218278514 36 - 0.000 0.152 11.585
ENSG00000135926 E016 25.6532984 0.0006332534 1.608775e-01 4.288847e-01 2 218278515 218278535 21 - 1.464 1.383 -0.280
ENSG00000135926 E017 29.6510859 0.0006413923 6.391735e-01 8.465200e-01 2 218278536 218278565 30 - 1.493 1.468 -0.086
ENSG00000135926 E018 27.9136276 0.0219338634 6.975931e-01 8.765786e-01 2 218279038 218279091 54 - 1.473 1.439 -0.114
ENSG00000135926 E019 25.6835724 0.0084264471 3.803866e-01 6.669192e-01 2 218279289 218279334 46 - 1.380 1.443 0.219
ENSG00000135926 E020 17.1838347 0.0008719700 2.647881e-01 5.578112e-01 2 218279335 218279337 3 - 1.202 1.282 0.283
ENSG00000135926 E021 20.5076255 0.0063567846 4.118834e-01 6.934669e-01 2 218279338 218279353 16 - 1.287 1.348 0.213
ENSG00000135926 E022 0.3728195 0.0166921069 8.014451e-01   2 218279354 218279539 186 - 0.110 0.152 0.540
ENSG00000135926 E023 23.0429187 0.0006049506 9.205476e-01 9.752146e-01 2 218280026 218280053 28 - 1.369 1.376 0.023
ENSG00000135926 E024 20.3200262 0.0006655044 9.268741e-01 9.782018e-01 2 218280054 218280058 5 - 1.324 1.319 -0.019
ENSG00000135926 E025 18.4677979 0.0007052389 8.832082e-01 9.606533e-01 2 218280059 218280076 18 - 1.287 1.278 -0.033
ENSG00000135926 E026 18.0294870 0.0007798509 1.767052e-01 4.510398e-01 2 218280077 218280109 33 - 1.324 1.232 -0.322
ENSG00000135926 E027 11.0231450 0.0028253702 2.035658e-01 4.861891e-01 2 218280110 218280124 15 - 1.134 1.025 -0.395
ENSG00000135926 E028 8.9319758 0.0020657116 1.438755e-01 4.039004e-01 2 218280125 218280126 2 - 1.065 0.930 -0.499
ENSG00000135926 E029 6.1815743 0.0023611558 1.289058e-07 7.353584e-06 2 218280127 218280992 866 - 0.332 1.017 3.032
ENSG00000135926 E030 14.9486026 0.0016572250 1.192003e-01 3.648257e-01 2 218281940 218282003 64 - 1.261 1.144 -0.412
ENSG00000135926 E031 12.4340825 0.0012399218 7.628312e-01 9.074516e-01 2 218282004 218282117 114 - 1.134 1.111 -0.086
ENSG00000135926 E032 14.3888609 0.0009254436 6.054707e-01 8.280558e-01 2 218282118 218282181 64 - 1.202 1.163 -0.138
ENSG00000135926 E033 0.0000000       2 218282182 218282208 27 -      
ENSG00000135926 E034 0.0000000       2 218284039 218284136 98 -      
ENSG00000135926 E035 0.0000000       2 218284137 218284160 24 -      
ENSG00000135926 E036 0.0000000       2 218284161 218284266 106 -      
ENSG00000135926 E037 1.2332554 0.0173032093 8.958465e-01 9.657523e-01 2 218285763 218285934 172 - 0.332 0.353 0.126
ENSG00000135926 E038 0.1187032 0.0118464445 3.879446e-01   2 218285935 218285938 4 - 0.110 0.000 -12.083
ENSG00000135926 E039 0.0000000       2 218285939 218286008 70 -      
ENSG00000135926 E040 0.6247610 0.0148684531 3.088664e-01 6.022080e-01 2 218286340 218286849 510 - 0.110 0.264 1.540
ENSG00000135926 E041 0.1187032 0.0118464445 3.879446e-01   2 218287207 218287303 97 - 0.110 0.000 -12.083
ENSG00000135926 E042 0.0000000       2 218289966 218290089 124 -      
ENSG00000135926 E043 11.3022435 0.0012645190 4.909181e-01 7.533911e-01 2 218292466 218292586 121 - 1.116 1.058 -0.208

Help

Please Click HERE to learn more details about the results from DEXseq.