ENSG00000135932

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258418 ENSG00000135932 No_inf pgKDN_inf CAB39 protein_coding protein_coding 85.82248 66.15794 102.8498 0.4478592 0.5436021 0.6364749 33.039183 16.063709 43.73942 0.5693655 1.805792 1.4445611 0.37095000 0.242775 0.425500 0.182725 0.001586745 0.001586745 FALSE TRUE
MSTRG.17724.2 ENSG00000135932 No_inf pgKDN_inf CAB39 protein_coding   85.82248 66.15794 102.8498 0.4478592 0.5436021 0.6364749 1.661842 4.985525 0.00000 1.9300455 0.000000 -8.9644924 0.02496667 0.074900 0.000000 -0.074900 0.009785633 0.001586745 FALSE TRUE
MSTRG.17724.6 ENSG00000135932 No_inf pgKDN_inf CAB39 protein_coding   85.82248 66.15794 102.8498 0.4478592 0.5436021 0.6364749 48.359189 42.468841 56.26723 1.8918297 2.444048 0.4058069 0.57100833 0.642400 0.546925 -0.095475 0.433206003 0.001586745 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000135932 E001 0.2435110 1.634739e-02 7.710756e-01   2 230712842 230712866 25 + 0.080 0.112 0.543
ENSG00000135932 E002 40.1713875 3.682995e-04 1.201197e-02 9.057089e-02 2 230712867 230713230 364 + 1.657 1.536 -0.412
ENSG00000135932 E003 0.4890031 1.580632e-02 7.109218e-01   2 230713548 230713802 255 + 0.148 0.202 0.542
ENSG00000135932 E004 1.2057798 5.453245e-02 5.105424e-01 7.680560e-01 2 230713803 230714058 256 + 0.384 0.276 -0.680
ENSG00000135932 E005 36.2156745 6.338760e-04 2.157059e-04 4.445502e-03 2 230759959 230760115 157 + 1.637 1.445 -0.657
ENSG00000135932 E006 0.3730368 1.645139e-02 3.775232e-01   2 230779006 230779450 445 + 0.080 0.202 1.542
ENSG00000135932 E007 0.1265070 1.228721e-02 3.659173e-01   2 230782732 230782758 27 + 0.000 0.112 9.028
ENSG00000135932 E008 18.6091092 7.999877e-04 3.558594e-02 1.806732e-01 2 230790872 230790897 26 + 1.344 1.198 -0.514
ENSG00000135932 E009 48.5765662 3.184964e-04 3.654905e-02 1.838669e-01 2 230790898 230791036 139 + 1.727 1.636 -0.309
ENSG00000135932 E010 48.6096020 1.645680e-03 6.055025e-02 2.469912e-01 2 230793213 230793331 119 + 1.725 1.639 -0.293
ENSG00000135932 E011 73.5655627 2.140986e-04 1.379614e-02 9.902924e-02 2 230798729 230798897 169 + 1.903 1.816 -0.293
ENSG00000135932 E012 1.4339822 3.062617e-01 2.052718e-01 4.885743e-01 2 230798898 230799124 227 + 0.481 0.202 -1.779
ENSG00000135932 E013 39.8627759 8.271614e-03 8.235291e-01 9.359255e-01 2 230810263 230810322 60 + 1.612 1.599 -0.046
ENSG00000135932 E014 0.0000000       2 230813983 230814048 66 +      
ENSG00000135932 E015 37.5029071 2.370576e-03 3.354742e-01 6.272882e-01 2 230814049 230814114 66 + 1.601 1.551 -0.172
ENSG00000135932 E016 65.9244687 3.676009e-04 2.116400e-01 4.966752e-01 2 230817754 230817897 144 + 1.840 1.793 -0.156
ENSG00000135932 E017 1.6327265 5.698785e-02 2.640617e-03 3.133532e-02 2 230817898 230818182 285 + 0.148 0.628 3.002
ENSG00000135932 E018 1146.9696743 5.510956e-05 2.555680e-10 2.422461e-08 2 230818516 230821075 2560 + 3.042 3.072 0.102

Help

Please Click HERE to learn more details about the results from DEXseq.