ENSG00000136068

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000295956 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.6349459 0.1780402 0.9867701 0.1780402 0.9867701 2.4062197 0.06680833 0.020300 0.109150 0.088850 1.00000000 0.04003012 FALSE TRUE
ENST00000466455 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.8666735 1.6507694 0.9492510 1.6507694 0.9492510 -0.7918716 0.06565833 0.117500 0.079475 -0.038025 1.00000000 0.04003012 FALSE FALSE
ENST00000475487 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding retained_intron 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.4766336 0.2037216 1.2261791 0.2037216 0.7226275 2.5320828 0.04337500 0.023250 0.106875 0.083625 0.81123412 0.04003012 FALSE TRUE
ENST00000484981 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding_CDS_not_defined 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.5933838 1.7801514 0.0000000 0.7603531 0.0000000 -7.4839378 0.06450833 0.193525 0.000000 -0.193525 0.04003012 0.04003012 FALSE TRUE
ENST00000490882 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.7208716 0.2417015 0.6767797 0.2417015 0.3967399 1.4481333 0.07190833 0.031025 0.059025 0.028000 0.83637610 0.04003012 FALSE TRUE
ENST00000493452 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 0.7561857 0.2780708 0.9717128 0.2780708 0.6525156 1.7688777 0.07754167 0.046650 0.085450 0.038800 0.83424814 0.04003012 FALSE TRUE
ENST00000682297 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding protein_coding_CDS_not_defined 10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 2.6767800 0.3459164 3.7687440 0.3459164 0.4729972 3.4082963 0.26814167 0.058050 0.352900 0.294850 0.05427338 0.04003012 FALSE TRUE
MSTRG.20307.16 ENSG00000136068 No_inf pgKDN_inf FLNB protein_coding   10.0185 9.142149 10.97126 1.736244 0.6581311 0.2628617 1.4422319 2.1347975 0.5966760 0.6340736 0.5966760 -1.8218434 0.14641667 0.227175 0.049950 -0.177225 0.14535860 0.04003012 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136068 E001 0.0000000       3 58008398 58008399 2 +      
ENSG00000136068 E002 0.0000000       3 58008400 58008405 6 +      
ENSG00000136068 E003 0.1271363 0.0122923568 0.361681880   3 58008406 58008421 16 + 0.000 0.113 10.647
ENSG00000136068 E004 1.9415272 0.0077926300 0.806041166 0.92815130 3 58008422 58008856 435 + 0.478 0.446 -0.164
ENSG00000136068 E005 2.4324545 0.0056618349 0.962856868 0.99200982 3 58077046 58077294 249 + 0.533 0.530 -0.012
ENSG00000136068 E006 0.0000000       3 58078329 58078519 191 +      
ENSG00000136068 E007 2.1507703 0.0062684716 0.030040980 0.16306665 3 58078717 58078814 98 + 0.603 0.278 -1.749
ENSG00000136068 E008 2.7476217 0.0054148479 0.017780222 0.11733250 3 58081629 58081776 148 + 0.682 0.341 -1.675
ENSG00000136068 E009 1.3159535 0.0097334197 0.114488621 0.35647323 3 58094836 58094954 119 + 0.448 0.203 -1.597
ENSG00000136068 E010 1.4433158 0.0577098338 0.294048989 0.58746622 3 58096141 58096218 78 + 0.448 0.278 -1.012
ENSG00000136068 E011 2.9047813 0.0742670999 0.550417785 0.79484576 3 58097815 58097977 163 + 0.624 0.530 -0.427
ENSG00000136068 E012 3.0033060 0.1766815158 0.177647759 0.45226595 3 58098711 58098908 198 + 0.682 0.446 -1.089
ENSG00000136068 E013 0.0000000       3 58099638 58099735 98 +      
ENSG00000136068 E014 1.2066273 0.0103627624 0.495579868 0.75673794 3 58102203 58102340 138 + 0.381 0.278 -0.649
ENSG00000136068 E015 1.3256476 0.0097450887 0.364209899 0.65297001 3 58103959 58104085 127 + 0.416 0.278 -0.842
ENSG00000136068 E016 1.4601721 0.0101469857 0.933968715 0.98101385 3 58105080 58105216 137 + 0.381 0.397 0.088
ENSG00000136068 E017 0.2543986 0.0160759360 0.136258499   3 58105217 58106354 1138 + 0.000 0.203 14.158
ENSG00000136068 E018 1.6975509 0.0076801130 0.714725429 0.88505948 3 58106680 58106873 194 + 0.448 0.397 -0.275
ENSG00000136068 E019 0.0000000       3 58106874 58108103 1230 +      
ENSG00000136068 E020 1.4609895 0.0149050017 0.937158902 0.98208705 3 58108458 58108571 114 + 0.381 0.397 0.088
ENSG00000136068 E021 2.9843197 0.0137609746 0.009925270 0.07987310 3 58109179 58109322 144 + 0.717 0.341 -1.819
ENSG00000136068 E022 2.4206858 0.0080350939 0.620204767 0.83578870 3 58109576 58109699 124 + 0.557 0.490 -0.320
ENSG00000136068 E023 3.7627262 0.0041920504 0.842273637 0.94343122 3 58110010 58110170 161 + 0.682 0.661 -0.090
ENSG00000136068 E024 0.0000000       3 58110171 58111467 1297 +      
ENSG00000136068 E025 3.2575119 0.0046889007 0.245158786 0.53564488 3 58111791 58111881 91 + 0.682 0.530 -0.675
ENSG00000136068 E026 3.6329053 0.0868044828 0.538179943 0.78704439 3 58112149 58112318 170 + 0.700 0.600 -0.427
ENSG00000136068 E027 2.7654626 0.0054975656 0.151604663 0.41495428 3 58118872 58118989 118 + 0.645 0.446 -0.929
ENSG00000136068 E028 0.0000000       3 58118990 58119487 498 +      
ENSG00000136068 E029 4.5481437 0.0184788181 0.017135334 0.11445515 3 58121241 58121503 263 + 0.846 0.530 -1.334
ENSG00000136068 E030 10.9599234 0.0549107021 0.064680720 0.25637493 3 58123093 58123690 598 + 1.154 0.927 -0.828
ENSG00000136068 E031 4.3512306 0.0035745611 0.378829076 0.66565998 3 58124332 58124505 174 + 0.765 0.661 -0.427
ENSG00000136068 E032 2.9916256 0.0050438404 0.030000987 0.16301362 3 58125581 58125743 163 + 0.700 0.397 -1.427
ENSG00000136068 E033 4.7124385 0.0031141232 0.358696353 0.64815819 3 58126602 58126762 161 + 0.794 0.689 -0.427
ENSG00000136068 E034 3.5090554 0.0042656967 0.507017418 0.76561518 3 58130741 58130908 168 + 0.682 0.600 -0.353
ENSG00000136068 E035 2.9679763 0.0130549066 0.036015431 0.18209958 3 58130909 58131926 1018 + 0.448 0.739 1.310
ENSG00000136068 E036 1.4971951 0.2274825928 0.088138533 0.30793339 3 58131927 58132019 93 + 0.205 0.567 2.158
ENSG00000136068 E037 0.5081066 0.0157699194 0.017204794 0.11475681 3 58132020 58132077 58 + 0.000 0.341 15.029
ENSG00000136068 E038 1.9767509 0.0301973169 0.094253089 0.31953272 3 58132078 58132762 685 + 0.343 0.600 1.310
ENSG00000136068 E039 0.0000000       3 58132763 58132807 45 +      
ENSG00000136068 E040 0.7341201 0.3318742969 0.819241620 0.93420257 3 58132808 58132836 29 + 0.205 0.278 0.575
ENSG00000136068 E041 2.6753650 0.0069056551 0.973545534 0.99528404 3 58132837 58132931 95 + 0.557 0.567 0.043
ENSG00000136068 E042 5.4894137 0.0026440983 0.595114606 0.82198719 3 58134616 58134772 157 + 0.779 0.843 0.251
ENSG00000136068 E043 6.5578058 0.0023615945 0.810293515 0.93008680 3 58135979 58136168 190 + 0.882 0.862 -0.079
ENSG00000136068 E044 8.0637059 0.0141706847 0.319092943 0.61182263 3 58138282 58138529 248 + 0.904 1.011 0.398
ENSG00000136068 E045 1.7519611 0.0079659336 0.004027419 0.04264028 3 58138530 58141013 2484 + 0.205 0.632 2.448
ENSG00000136068 E046 1.7404477 0.0506208870 0.029904372 0.16263670 3 58141158 58141857 700 + 0.256 0.600 1.895
ENSG00000136068 E047 1.9515047 0.0461912285 0.797011390 0.92335809 3 58141858 58141896 39 + 0.448 0.490 0.210
ENSG00000136068 E048 1.8328651 0.0091043066 0.634093243 0.84362609 3 58141897 58141929 33 + 0.416 0.490 0.380
ENSG00000136068 E049 1.1269525 0.2674718836 0.096155665 0.32299517 3 58141930 58142649 720 + 0.147 0.490 2.380
ENSG00000136068 E050 4.4603355 0.0143366382 0.100069049 0.33052274 3 58142650 58142752 103 + 0.807 0.600 -0.860
ENSG00000136068 E051 6.0218025 0.0292593522 0.057434419 0.23966483 3 58143473 58143613 141 + 0.926 0.689 -0.936
ENSG00000136068 E052 0.3809703 0.0280179526 0.048966431   3 58144398 58145920 1523 + 0.000 0.278 14.652
ENSG00000136068 E053 4.9624296 0.0029328463 0.404336257 0.68712624 3 58145921 58146049 129 + 0.807 0.714 -0.374
ENSG00000136068 E054 0.0000000       3 58146678 58146819 142 +      
ENSG00000136068 E055 6.8321587 0.0310271796 0.424307373 0.70349197 3 58146820 58146993 174 + 0.846 0.943 0.367
ENSG00000136068 E056 4.7111147 0.0031167877 0.210006309 0.49443340 3 58148206 58148364 159 + 0.807 0.661 -0.597
ENSG00000136068 E057 8.1790417 0.0049926838 0.354546585 0.64427613 3 58148649 58148852 204 + 0.915 1.011 0.357
ENSG00000136068 E058 0.0000000       3 58149088 58149231 144 +      
ENSG00000136068 E059 0.1271363 0.0122923568 0.361681880   3 58149232 58149849 618 + 0.000 0.113 13.250
ENSG00000136068 E060 2.8537999 0.2367845228 0.118360303 0.36342981 3 58149850 58149865 16 + 0.381 0.762 1.766
ENSG00000136068 E061 6.3857954 0.0432459722 0.143450892 0.40336064 3 58149866 58149980 115 + 0.765 0.971 0.795
ENSG00000136068 E062 3.5274334 0.0041979677 0.925863659 0.97773821 3 58149981 58150002 22 + 0.645 0.661 0.071
ENSG00000136068 E063 7.6380544 0.0018924396 0.514563463 0.77108576 3 58150105 58150227 123 + 0.956 0.896 -0.225
ENSG00000136068 E064 0.1170040 0.0117444686 0.798691030   3 58150228 58151391 1164 + 0.079 0.000 -13.314
ENSG00000136068 E065 0.0000000       3 58152708 58152807 100 +      
ENSG00000136068 E066 0.0000000       3 58152808 58152854 47 +      
ENSG00000136068 E067 0.5071304 0.0165437748 0.017135185 0.11445515 3 58152855 58153374 520 + 0.000 0.341 15.028
ENSG00000136068 E068 12.1143789 0.0012132643 0.069022572 0.26544947 3 58153375 58153641 267 + 1.043 1.194 0.544
ENSG00000136068 E069 0.0000000       3 58154610 58154790 181 +      
ENSG00000136068 E070 6.3047296 0.0139744225 0.565083082 0.80405356 3 58154791 58154928 138 + 0.882 0.824 -0.223
ENSG00000136068 E071 4.4155393 0.0302178034 0.004003851 0.04244415 3 58155960 58156026 67 + 0.859 0.446 -1.796
ENSG00000136068 E072 4.9180459 0.0131669345 0.016826136 0.11311240 3 58156027 58156075 49 + 0.870 0.567 -1.257
ENSG00000136068 E073 5.2981437 0.0025745485 0.067819548 0.26278714 3 58159554 58159686 133 + 0.870 0.661 -0.842
ENSG00000136068 E074 0.0000000       3 58159687 58159691 5 +      
ENSG00000136068 E075 0.0000000       3 58163154 58163330 177 +      
ENSG00000136068 E076 0.0000000       3 58163331 58163512 182 +      
ENSG00000136068 E077 0.0000000       3 58164573 58165475 903 +      
ENSG00000136068 E078 0.0000000       3 58165476 58165580 105 +      
ENSG00000136068 E079 1.5852998 0.0090440115 0.683770957 0.86909959 3 58165581 58168439 2859 + 0.381 0.446 0.351
ENSG00000136068 E080 8.3869483 0.0029305179 0.811313055 0.93052452 3 58168440 58168658 219 + 0.974 0.957 -0.064
ENSG00000136068 E081 1.8683372 0.0078628203 0.010786603 0.08442383 3 58168659 58169589 931 + 0.256 0.632 2.032
ENSG00000136068 E082 7.7155949 0.0028370936 0.103079975 0.33553325 3 58169590 58169793 204 + 0.859 1.023 0.619
ENSG00000136068 E083 62.2106853 0.0006588363 0.000858359 0.01333666 3 58170575 58172251 1677 + 1.740 1.861 0.409

Help

Please Click HERE to learn more details about the results from DEXseq.