ENSG00000136108

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258607 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding protein_coding 24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 13.3246391 9.2186752 19.6798061 3.3471653 3.8954048 1.09325344 0.54485000 0.507775 0.637400 0.129625 0.8583501459 0.0009300085 FALSE  
ENST00000378034 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding protein_coding 24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 1.3305045 1.2329818 1.7764488 0.4662668 0.3079423 0.52328937 0.05558333 0.065325 0.057050 -0.008275 1.0000000000 0.0009300085 FALSE  
ENST00000378037 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding protein_coding 24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 5.5142910 4.2879541 4.2362101 3.7608351 2.5446639 -0.01747431 0.23890833 0.224825 0.130100 -0.094725 0.8798224253 0.0009300085 FALSE  
ENST00000459902 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding retained_intron 24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 0.7115769 1.5926305 0.0000000 0.6112620 0.0000000 -7.32429800 0.03613333 0.085100 0.000000 -0.085100 0.0009300085 0.0009300085 FALSE  
MSTRG.7862.1 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding   24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 0.6857682 1.7370932 0.3202114 1.5440427 0.3202114 -2.40349488 0.03380833 0.090800 0.010625 -0.080175 0.8032372003 0.0009300085 FALSE  
MSTRG.7862.6 ENSG00000136108 No_inf pgKDN_inf CKAP2 protein_coding   24.07892 18.55026 31.18657 0.416888 0.8286629 0.7491703 1.8538561 0.3146616 4.6892192 0.3146616 3.7666831 3.85541224 0.06346667 0.017125 0.149650 0.132525 0.8294784714 0.0009300085 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136108 E001 0.2537694 0.0159636564 0.126934264   13 52455429 52455438 10 + 0.000 0.206 11.232
ENSG00000136108 E002 0.2537694 0.0159636564 0.126934264   13 52455439 52455466 28 + 0.000 0.206 13.025
ENSG00000136108 E003 0.4997349 0.0168469943 0.155696678   13 52455467 52455477 11 + 0.078 0.281 2.210
ENSG00000136108 E004 8.9042112 0.0391615897 0.422177379 0.70145867 13 52455478 52455626 149 + 0.948 1.043 0.349
ENSG00000136108 E005 0.4896324 0.0160994315 0.669700033   13 52455876 52455911 36 + 0.144 0.206 0.625
ENSG00000136108 E006 0.0000000       13 52455972 52456007 36 +      
ENSG00000136108 E007 0.3624961 0.0167185334 0.891422197   13 52456008 52456179 172 + 0.144 0.115 -0.375
ENSG00000136108 E008 0.4979070 0.0231301699 0.156810961   13 52456503 52456522 20 + 0.078 0.281 2.210
ENSG00000136108 E009 11.7755436 0.0057089740 0.967692957 0.99349493 13 52456523 52456607 85 + 1.101 1.099 -0.009
ENSG00000136108 E010 1.3308387 0.0123071381 0.839272181 0.94236020 13 52460896 52460898 3 + 0.376 0.346 -0.182
ENSG00000136108 E011 14.0675678 0.0501861770 0.874433109 0.95707278 13 52460899 52460974 76 + 1.181 1.158 -0.084
ENSG00000136108 E012 111.5642109 0.0003683258 0.144371124 0.40451515 13 52461058 52461926 869 + 2.060 2.022 -0.125
ENSG00000136108 E013 32.6818362 0.0005537556 0.896812212 0.96596309 13 52462363 52462567 205 + 1.523 1.517 -0.018
ENSG00000136108 E014 35.9813847 0.0072351610 0.147566196 0.40899907 13 52465295 52465465 171 + 1.594 1.509 -0.288
ENSG00000136108 E015 2.5775007 0.0054170836 0.235297722 0.52455451 13 52465466 52465843 378 + 0.473 0.638 0.763
ENSG00000136108 E016 18.4381888 0.0028848370 0.527665566 0.77953422 13 52468278 52468347 70 + 1.299 1.256 -0.152
ENSG00000136108 E017 1.1321123 0.0115574426 0.002195039 0.02738543 13 52473535 52473828 294 + 0.078 0.536 3.625
ENSG00000136108 E018 47.3822327 0.0189469380 0.333544973 0.62556082 13 52473829 52474084 256 + 1.701 1.642 -0.201
ENSG00000136108 E019 193.6681489 0.0015893522 0.037498167 0.18665677 13 52474895 52476628 1734 + 2.264 2.307 0.144

Help

Please Click HERE to learn more details about the results from DEXseq.