ENSG00000136143

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000643246 ENSG00000136143 No_inf pgKDN_inf SUCLA2 protein_coding protein_coding 26.90888 26.40665 28.77721 1.354156 0.6021823 0.1239802 0.9340469 2.802141 0.000000 1.619790 0.0000000 -8.1355250 0.03526667 0.10580 0.00000 -0.10580 0.48104321 0.02279144   FALSE
ENST00000646932 ENSG00000136143 No_inf pgKDN_inf SUCLA2 protein_coding protein_coding 26.90888 26.40665 28.77721 1.354156 0.6021823 0.1239802 16.4365040 12.019108 19.989404 1.573033 0.3148618 0.7334273 0.61380000 0.45080 0.69555 0.24475 0.02279144 0.02279144 FALSE TRUE
MSTRG.7787.11 ENSG00000136143 No_inf pgKDN_inf SUCLA2 protein_coding   26.90888 26.40665 28.77721 1.354156 0.6021823 0.1239802 1.5476813 2.220056 1.347099 1.344505 0.7865320 -0.7165537 0.06033333 0.09245 0.04540 -0.04705 0.98848950 0.02279144 FALSE TRUE
MSTRG.7787.24 ENSG00000136143 No_inf pgKDN_inf SUCLA2 protein_coding   26.90888 26.40665 28.77721 1.354156 0.6021823 0.1239802 5.1026850 6.232417 4.500867 2.227114 0.9622699 -0.4687002 0.18235833 0.22965 0.15810 -0.07155 0.84712738 0.02279144   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136143 E001 0.0000000       13 47745736 47746437 702 -      
ENSG00000136143 E002 0.4994828 0.0169501831 0.203815542   13 47746438 47747424 987 - 0.084 0.265 1.972
ENSG00000136143 E003 0.0000000       13 47797002 47797212 211 -      
ENSG00000136143 E004 0.0000000       13 47798259 47798508 250 -      
ENSG00000136143 E005 0.0000000       13 47807394 47807499 106 -      
ENSG00000136143 E006 0.1186381 0.0117453116 0.708498165   13 47905329 47905398 70 - 0.084 0.000 -11.754
ENSG00000136143 E007 0.0000000       13 47907018 47907135 118 -      
ENSG00000136143 E008 0.0000000       13 47907331 47907452 122 -      
ENSG00000136143 E009 0.0000000       13 47932694 47932783 90 -      
ENSG00000136143 E010 1.3432369 0.0102216339 0.874115694 0.95698783 13 47934915 47935821 907 - 0.359 0.380 0.124
ENSG00000136143 E011 0.3538994 0.0343327165 0.171952624   13 47936491 47936501 11 - 0.215 0.000 -13.126
ENSG00000136143 E012 0.7337727 0.0277497418 0.736181612 0.89534028 13 47936502 47936617 116 - 0.215 0.265 0.388
ENSG00000136143 E013 1.0932802 0.0147642674 0.933685609 0.98091824 13 47936618 47936773 156 - 0.316 0.326 0.066
ENSG00000136143 E014 0.0000000       13 47939267 47939363 97 -      
ENSG00000136143 E015 0.1272623 0.0123776370 0.405530991   13 47942656 47942660 5 - 0.000 0.107 11.406
ENSG00000136143 E016 0.6080157 0.0198242617 0.890806517 0.96365730 13 47942661 47942664 4 - 0.215 0.193 -0.198
ENSG00000136143 E017 1.3503152 0.0101107274 0.449232293 0.72301317 13 47942665 47942688 24 - 0.316 0.428 0.650
ENSG00000136143 E018 3.5871308 0.0537487607 0.038189994 0.18866363 13 47942689 47942728 40 - 0.497 0.801 1.313
ENSG00000136143 E019 7.1282172 0.0027042444 0.065379542 0.25749819 13 47942729 47942780 52 - 0.817 0.998 0.687
ENSG00000136143 E020 68.9253313 0.0003086974 0.016563754 0.11207496 13 47942781 47943344 564 - 1.809 1.881 0.244
ENSG00000136143 E021 12.9695165 0.0011709565 0.160003169 0.42756830 13 47943345 47943360 16 - 1.192 1.076 -0.415
ENSG00000136143 E022 21.9289343 0.0008119975 0.941542989 0.98355830 13 47943361 47943445 85 - 1.358 1.359 0.000
ENSG00000136143 E023 0.1265070 0.0123083623 0.405553554   13 47945731 47945939 209 - 0.000 0.107 11.406
ENSG00000136143 E024 18.4307107 0.0008694224 0.507821388 0.76618566 13 47948940 47949028 89 - 1.268 1.308 0.138
ENSG00000136143 E025 18.9993141 0.0008386919 0.848295502 0.94628575 13 47949483 47949603 121 - 1.307 1.289 -0.060
ENSG00000136143 E026 5.0757774 0.0045004212 0.112919014 0.35352494 13 47954140 47954142 3 - 0.858 0.666 -0.770
ENSG00000136143 E027 19.8865491 0.0092407672 0.078900342 0.28791685 13 47954143 47954282 140 - 1.375 1.236 -0.483
ENSG00000136143 E028 0.0000000       13 47954283 47954395 113 -      
ENSG00000136143 E029 11.7033259 0.0145093273 0.926820984 0.97816494 13 47954396 47954452 57 - 1.099 1.106 0.025
ENSG00000136143 E030 14.5263489 0.0170586011 0.697477213 0.87655014 13 47954453 47954557 105 - 1.173 1.207 0.120
ENSG00000136143 E031 0.4814165 0.0188468314 0.473763471   13 47956840 47956872 33 - 0.215 0.107 -1.198
ENSG00000136143 E032 0.4814165 0.0188468314 0.473763471   13 47956873 47956878 6 - 0.215 0.107 -1.198
ENSG00000136143 E033 0.6067014 0.0159049642 0.890369637 0.96339117 13 47965578 47965640 63 - 0.215 0.193 -0.198
ENSG00000136143 E034 14.1968629 0.0013100263 0.254603240 0.54629902 13 47968595 47968733 139 - 1.141 1.222 0.288
ENSG00000136143 E035 0.0000000       13 47971453 47971680 228 -      
ENSG00000136143 E036 0.0000000       13 47971681 47971883 203 -      
ENSG00000136143 E037 0.0000000       13 47971884 47972086 203 -      
ENSG00000136143 E038 13.9231436 0.0024598093 0.461170381 0.73207704 13 47973264 47973392 129 - 1.148 1.200 0.185
ENSG00000136143 E039 0.9455859 0.0117988048 0.006449794 0.05944347 13 47987634 47988540 907 - 0.433 0.000 -14.348
ENSG00000136143 E040 18.6519139 0.0012669571 0.026685054 0.15148213 13 47988541 47988703 163 - 1.354 1.200 -0.543
ENSG00000136143 E041 13.1405248 0.0032804360 0.508556652 0.76675876 13 47988882 47988981 100 - 1.174 1.115 -0.209
ENSG00000136143 E042 0.2362687 0.0156498172 0.352954671   13 47991503 47991678 176 - 0.155 0.000 -12.660
ENSG00000136143 E043 0.4907934 0.1021149657 0.794400764   13 47994800 47994896 97 - 0.155 0.193 0.387
ENSG00000136143 E044 7.1406390 0.0565538740 0.197225434 0.47846152 13 47996843 47996912 70 - 0.981 0.801 -0.688
ENSG00000136143 E045 4.7172323 0.0036940668 0.218184654 0.50464600 13 47996913 47997023 111 - 0.817 0.666 -0.613
ENSG00000136143 E046 0.1187032 0.0119005688 0.708200698   13 48000907 48001179 273 - 0.084 0.000 -11.753
ENSG00000136143 E047 5.5812547 0.0032632829 0.403157176 0.68618654 13 48001180 48001305 126 - 0.858 0.760 -0.383
ENSG00000136143 E048 2.2156339 0.0067055863 0.293606811 0.58717978 13 48004701 48005001 301 - 0.433 0.580 0.709
ENSG00000136143 E049 0.1265070 0.0123083623 0.405553554   13 48015171 48015218 48 - 0.000 0.107 11.406
ENSG00000136143 E050 0.3635961 0.0168415532 0.769599825   13 48015219 48015248 30 - 0.155 0.107 -0.613
ENSG00000136143 E051 1.0964576 0.0117498937 0.935135405 0.98133268 13 48037606 48037968 363 - 0.316 0.326 0.065

Help

Please Click HERE to learn more details about the results from DEXseq.