ENSG00000136167

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323076 ENSG00000136167 No_inf pgKDN_inf LCP1 protein_coding protein_coding 906.3184 626.4907 1114.08 4.670607 6.998357 0.830478 555.1112 328.1912 697.4300 2.080396 4.336277 1.0874889 0.6013167 0.524025 0.626025 0.102000 1.763584e-07 1.260053e-08 FALSE TRUE
ENST00000674665 ENSG00000136167 No_inf pgKDN_inf LCP1 protein_coding protein_coding 906.3184 626.4907 1114.08 4.670607 6.998357 0.830478 308.4647 275.6734 355.2302 6.722083 6.479770 0.3657826 0.3532333 0.439875 0.318850 -0.121025 1.260053e-08 1.260053e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136167 E001 2.9658331 8.439500e-03 1.746250e-02 1.158596e-01 13 46125920 46125922 3 - 0.430 0.762 1.503
ENSG00000136167 E002 84.5321274 1.782972e-04 2.850045e-04 5.565326e-03 13 46125923 46125956 34 - 1.863 2.000 0.461
ENSG00000136167 E003 7810.4848084 2.183483e-04 2.274764e-26 1.048608e-23 13 46125957 46127723 1767 - 3.859 3.915 0.185
ENSG00000136167 E004 770.1257679 3.313055e-05 4.181205e-03 4.379881e-02 13 46130814 46130938 125 - 2.882 2.866 -0.053
ENSG00000136167 E005 781.6691731 2.192824e-04 1.457087e-03 1.999148e-02 13 46134127 46134250 124 - 2.891 2.868 -0.079
ENSG00000136167 E006 732.1005328 4.193240e-04 6.989238e-03 6.299878e-02 13 46142292 46142425 134 - 2.862 2.840 -0.073
ENSG00000136167 E007 0.1265070 1.228679e-02 3.210122e-01   13 46142726 46142839 114 - 0.000 0.120 11.555
ENSG00000136167 E008 600.6578812 4.427248e-04 5.606065e-03 5.382855e-02 13 46143290 46143404 115 - 2.778 2.752 -0.088
ENSG00000136167 E009 459.3472724 2.639136e-04 4.439954e-05 1.209416e-03 13 46144442 46144520 79 - 2.670 2.621 -0.164
ENSG00000136167 E010 0.9810900 1.204075e-02 4.922141e-01 7.544354e-01 13 46146906 46146907 2 - 0.243 0.357 0.766
ENSG00000136167 E011 740.1113957 4.158837e-05 1.071735e-06 4.952103e-05 13 46146908 46147103 196 - 2.874 2.833 -0.134
ENSG00000136167 E012 383.2831436 5.662287e-05 2.335748e-03 2.866353e-02 13 46148352 46148447 96 - 2.586 2.553 -0.110
ENSG00000136167 E013 0.4907934 9.842912e-02 6.438304e-01   13 46148782 46148808 27 - 0.138 0.214 0.766
ENSG00000136167 E014 486.3412147 3.321018e-04 1.156956e-01 3.586126e-01 13 46150936 46151078 143 - 2.680 2.671 -0.030
ENSG00000136167 E015 143.5680332 3.168537e-04 1.027943e-01 3.351737e-01 13 46152780 46152780 1 - 2.160 2.132 -0.094
ENSG00000136167 E016 538.1901140 4.272914e-04 6.060749e-05 1.556915e-03 13 46152781 46152945 165 - 2.738 2.691 -0.158
ENSG00000136167 E017 0.8460175 2.696972e-02 6.119224e-01 8.311321e-01 13 46153139 46153265 127 - 0.287 0.214 -0.556
ENSG00000136167 E018 395.4865559 2.342531e-03 1.281160e-04 2.900213e-03 13 46154805 46154886 82 - 2.617 2.534 -0.277
ENSG00000136167 E019 367.6955021 1.715732e-03 1.255878e-05 4.158044e-04 13 46156438 46156570 133 - 2.588 2.499 -0.296
ENSG00000136167 E020 0.0000000       13 46158522 46158651 130 -      
ENSG00000136167 E021 0.0000000       13 46158826 46158855 30 -      
ENSG00000136167 E022 0.0000000       13 46158856 46158989 134 -      
ENSG00000136167 E023 0.0000000       13 46159016 46159598 583 -      
ENSG00000136167 E024 0.0000000       13 46159599 46159686 88 -      
ENSG00000136167 E025 0.7371710 5.443702e-02 5.633382e-01 8.027023e-01 13 46168463 46168519 57 - 0.194 0.292 0.766
ENSG00000136167 E026 8.4358872 1.978179e-02 1.491419e-01 4.114276e-01 13 46182111 46182225 115 - 0.890 1.062 0.641
ENSG00000136167 E027 0.2363338 1.562946e-02 4.639945e-01   13 46183909 46183972 64 - 0.138 0.000 -12.197
ENSG00000136167 E028 0.1272623 1.232637e-02 3.209872e-01   13 46194024 46194105 82 - 0.000 0.120 11.553
ENSG00000136167 E029 0.1272623 1.232637e-02 3.209872e-01   13 46203101 46203230 130 - 0.000 0.120 11.553
ENSG00000136167 E030 0.0000000       13 46211293 46211348 56 -      
ENSG00000136167 E031 0.0000000       13 46211732 46211871 140 -      

Help

Please Click HERE to learn more details about the results from DEXseq.