ENSG00000136381

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258886 ENSG00000136381 No_inf pgKDN_inf IREB2 protein_coding protein_coding 21.42828 16.54369 25.28761 0.2759032 0.7986459 0.6118485 17.093239 6.989543 23.91471 2.163857 0.4907845 1.773169 0.7577833 0.416825 0.94685 0.530025 5.602709e-06 5.602709e-06 FALSE TRUE
ENST00000558570 ENSG00000136381 No_inf pgKDN_inf IREB2 protein_coding nonsense_mediated_decay 21.42828 16.54369 25.28761 0.2759032 0.7986459 0.6118485 2.548756 7.646269 0.00000 2.585983 0.0000000 -9.580498 0.1565167 0.469550 0.00000 -0.469550 4.250990e-03 5.602709e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136381 E001 0.0000000       15 78437431 78437721 291 +      
ENSG00000136381 E002 0.0000000       15 78438176 78438215 40 +      
ENSG00000136381 E003 0.0000000       15 78438216 78438227 12 +      
ENSG00000136381 E004 0.0000000       15 78438228 78438283 56 +      
ENSG00000136381 E005 1.6893346 0.0081249302 3.480306e-01 6.385528e-01 15 78438284 78438308 25 + 0.482 0.338 -0.792
ENSG00000136381 E006 2.6430713 0.0081708459 7.910061e-02 2.883822e-01 15 78438309 78438356 48 + 0.650 0.393 -1.236
ENSG00000136381 E007 1.1074335 0.0112700435 3.771946e-01 6.641729e-01 15 78438422 78438856 435 + 0.259 0.393 0.852
ENSG00000136381 E008 6.1723308 0.0021994513 2.779673e-01 5.712142e-01 15 78439795 78439876 82 + 0.899 0.778 -0.470
ENSG00000136381 E009 3.2878909 0.0260944260 9.967193e-01 1.000000e+00 15 78439877 78439881 5 + 0.629 0.627 -0.011
ENSG00000136381 E010 13.8523043 0.0009985926 7.769107e-01 9.142698e-01 15 78462922 78463087 166 + 1.178 1.153 -0.087
ENSG00000136381 E011 7.4162957 0.0376298756 8.482016e-01 9.462857e-01 15 78465251 78465298 48 + 0.931 0.906 -0.094
ENSG00000136381 E012 8.7015839 0.0015999500 1.245915e-01 3.741698e-01 15 78465299 78465388 90 + 1.041 0.890 -0.561
ENSG00000136381 E013 18.7479952 0.0080299629 9.864984e-02 3.277027e-01 15 78466271 78466489 219 + 1.342 1.212 -0.456
ENSG00000136381 E014 8.9279639 0.0539146784 9.925348e-02 3.290189e-01 15 78470532 78470601 70 + 1.072 0.856 -0.806
ENSG00000136381 E015 0.2458395 0.0163760018 7.718679e-01   15 78470720 78470948 229 + 0.081 0.112 0.530
ENSG00000136381 E016 12.2142901 0.0012278050 9.511640e-02 3.210067e-01 15 78471741 78471924 184 + 1.172 1.030 -0.513
ENSG00000136381 E017 10.9973984 0.0012097693 8.092134e-02 2.923060e-01 15 78473242 78473381 140 + 1.134 0.979 -0.566
ENSG00000136381 E018 6.9920012 0.0025720651 6.092677e-08 3.729880e-06 15 78473382 78476187 2806 + 0.562 1.135 2.256
ENSG00000136381 E019 19.8214857 0.0113731024 4.396559e-02 2.048942e-01 15 78476188 78476359 172 + 1.377 1.212 -0.577
ENSG00000136381 E020 0.7535991 0.0133529676 3.408209e-02 1.759364e-01 15 78476360 78476700 341 + 0.081 0.393 2.852
ENSG00000136381 E021 13.5809989 0.0010359198 3.680769e-01 6.566342e-01 15 78478297 78478397 101 + 1.189 1.116 -0.262
ENSG00000136381 E022 13.4775201 0.0322660482 6.266861e-01 8.396607e-01 15 78483318 78483419 102 + 1.178 1.126 -0.186
ENSG00000136381 E023 7.8427804 0.0435272264 1.813876e-01 4.573398e-01 15 78483420 78483434 15 + 1.007 0.838 -0.640
ENSG00000136381 E024 19.5588987 0.0007284448 9.081231e-03 7.551211e-02 15 78484761 78484920 160 + 1.377 1.196 -0.633
ENSG00000136381 E025 17.6021131 0.0007601012 2.584849e-03 3.085684e-02 15 78485705 78485840 136 + 1.346 1.126 -0.778
ENSG00000136381 E026 17.7480220 0.0044948753 2.474322e-02 1.445986e-01 15 78487733 78487817 85 + 1.334 1.162 -0.605
ENSG00000136381 E027 25.0741684 0.0018931467 1.132388e-01 3.539462e-01 15 78488180 78488336 157 + 1.452 1.352 -0.346
ENSG00000136381 E028 0.6270921 0.0149439124 7.703199e-02 2.839229e-01 15 78488337 78488646 310 + 0.081 0.338 2.530
ENSG00000136381 E029 16.2502896 0.0008227418 3.195107e-01 6.121736e-01 15 78488647 78488771 125 + 1.263 1.188 -0.265
ENSG00000136381 E030 14.2278668 0.0159917133 3.579495e-02 1.814782e-01 15 78490422 78490526 105 + 1.253 1.053 -0.716
ENSG00000136381 E031 21.4634902 0.0178624086 3.689288e-01 6.573726e-01 15 78490619 78490761 143 + 1.381 1.297 -0.291
ENSG00000136381 E032 23.4555254 0.0064717186 6.325907e-01 8.426179e-01 15 78493909 78494056 148 + 1.399 1.363 -0.124
ENSG00000136381 E033 13.6167235 0.0016586469 7.499948e-01 9.014575e-01 15 78494142 78494209 68 + 1.172 1.144 -0.098
ENSG00000136381 E034 13.3691810 0.0010342650 7.193334e-01 8.868075e-01 15 78494210 78494264 55 + 1.166 1.135 -0.110
ENSG00000136381 E035 29.7961553 0.0057410223 9.740790e-01 9.953877e-01 15 78497126 78497311 186 + 1.485 1.483 -0.006
ENSG00000136381 E036 0.2542726 0.2736020927 1.880868e-01   15 78497312 78497338 27 + 0.000 0.201 9.800
ENSG00000136381 E037 401.4239393 0.0001033512 5.589124e-14 8.588143e-12 15 78498033 78501453 3421 + 2.565 2.643 0.260

Help

Please Click HERE to learn more details about the results from DEXseq.