ENSG00000136448

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258960 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding protein_coding 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 8.867638 10.1351164 11.9012429 1.0924047 0.4652077 0.2315385 0.26840833 0.371450 0.316700 -0.054750 0.834271314 0.002377284 FALSE TRUE
ENST00000588455 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding retained_intron 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 2.577758 0.4424391 0.0000000 0.4424391 0.0000000 -5.4996518 0.06447500 0.015575 0.000000 -0.015575 0.831094387 0.002377284 FALSE FALSE
ENST00000590114 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding nonsense_mediated_decay 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 7.328425 0.4935298 10.4796476 0.4935298 0.9381391 4.3807453 0.19144167 0.019800 0.278200 0.258400 0.002377284 0.002377284 FALSE TRUE
ENST00000590310 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding protein_coding 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 1.440924 2.6802087 0.7497490 0.6127385 0.4931062 -1.8241232 0.04570833 0.096650 0.019150 -0.077500 0.221270191 0.002377284 FALSE TRUE
ENST00000592782 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding protein_coding 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 2.585054 0.6491889 0.3372398 0.6491889 0.3372398 -0.9247596 0.06775000 0.023825 0.008650 -0.015175 0.996273642 0.002377284 FALSE TRUE
ENST00000676828 ENSG00000136448 No_inf pgKDN_inf NMT1 protein_coding nonsense_mediated_decay 34.86491 27.26105 37.69683 0.8323643 0.8952155 0.4674556 10.338008 10.8056607 12.6442405 0.7543333 0.8344101 0.2264991 0.31010000 0.397225 0.335525 -0.061700 0.819533172 0.002377284 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136448 E001 0.0000000       17 44957992 44958062 71 +      
ENSG00000136448 E002 0.0000000       17 45051610 45051693 84 +      
ENSG00000136448 E003 0.0000000       17 45061271 45061282 12 +      
ENSG00000136448 E004 0.0000000       17 45061283 45061300 18 +      
ENSG00000136448 E005 0.0000000       17 45061301 45061303 3 +      
ENSG00000136448 E006 0.1187032 0.0118453653 5.759707e-01   17 45061304 45061305 2 + 0.092 0.000 -10.199
ENSG00000136448 E007 0.2452102 0.0165818235 9.576412e-01   17 45061306 45061316 11 + 0.092 0.098 0.095
ENSG00000136448 E008 0.6011245 0.1618586676 2.535038e-01 5.450675e-01 17 45061317 45061319 3 + 0.290 0.098 -1.906
ENSG00000136448 E009 0.9640940 0.0130318643 1.814411e-01 4.574536e-01 17 45061320 45061329 10 + 0.384 0.178 -1.490
ENSG00000136448 E010 1.7017994 0.1327211662 4.587455e-01 7.305632e-01 17 45061330 45061333 4 + 0.496 0.355 -0.754
ENSG00000136448 E011 20.8697877 0.0109350582 3.105112e-01 6.035866e-01 17 45061334 45061460 127 + 1.300 1.376 0.266
ENSG00000136448 E012 0.5080420 0.0160159296 3.836029e-02 1.891406e-01 17 45061679 45061910 232 + 0.000 0.304 13.698
ENSG00000136448 E013 0.0000000       17 45078083 45078149 67 +      
ENSG00000136448 E014 28.1811189 0.0125369818 3.792065e-01 6.660628e-01 17 45081644 45081752 109 + 1.496 1.432 -0.218
ENSG00000136448 E015 0.4816076 0.0153751271 3.530893e-01   17 45081753 45081995 243 + 0.233 0.098 -1.489
ENSG00000136448 E016 0.2373413 0.0157388566 2.666732e-01   17 45083658 45083755 98 + 0.168 0.000 -13.548
ENSG00000136448 E017 38.3560512 0.0053245133 3.039307e-02 1.640312e-01 17 45086508 45086652 145 + 1.651 1.530 -0.414
ENSG00000136448 E018 0.1272623 0.0124004777 5.026418e-01   17 45093631 45093684 54 + 0.000 0.098 11.815
ENSG00000136448 E019 28.6357297 0.0005860390 7.553795e-02 2.807569e-01 17 45093685 45093803 119 + 1.518 1.420 -0.337
ENSG00000136448 E020 21.7745216 0.0131605970 9.020020e-01 9.686128e-01 17 45096194 45096285 92 + 1.353 1.362 0.031
ENSG00000136448 E021 29.8211655 0.0015384920 7.189472e-01 8.868075e-01 17 45097128 45097244 117 + 1.499 1.478 -0.070
ENSG00000136448 E022 43.1690112 0.0003464285 1.040423e-01 3.370519e-01 17 45098382 45098552 171 + 1.680 1.607 -0.248
ENSG00000136448 E023 0.1176306 0.0117564546 5.759889e-01   17 45098553 45098843 291 + 0.092 0.000 -12.621
ENSG00000136448 E024 31.6882754 0.0004145581 1.139362e-01 3.554715e-01 17 45099405 45099513 109 + 1.554 1.471 -0.284
ENSG00000136448 E025 2.2502151 0.0061933771 1.117827e-02 8.652250e-02 17 45099514 45099819 306 + 0.289 0.657 1.903
ENSG00000136448 E026 40.9409461 0.0053200308 7.776765e-01 9.147120e-01 17 45102951 45103121 171 + 1.630 1.615 -0.051
ENSG00000136448 E027 0.7425506 0.1085787888 4.126370e-01 6.937804e-01 17 45103122 45103708 587 + 0.168 0.304 1.096
ENSG00000136448 E028 47.2802801 0.0004188154 5.707804e-02 2.388192e-01 17 45103709 45103876 168 + 1.723 1.641 -0.278
ENSG00000136448 E029 2.4953398 0.0474433101 3.139813e-02 1.672190e-01 17 45103877 45104120 244 + 0.339 0.681 1.680
ENSG00000136448 E030 0.8697489 0.0257570658 2.245656e-01 5.120786e-01 17 45104121 45104224 104 + 0.168 0.355 1.417
ENSG00000136448 E031 5.1073889 0.0033719367 1.387107e-03 1.926120e-02 17 45104225 45104858 634 + 0.557 0.934 1.543
ENSG00000136448 E032 35.1700459 0.0012219361 2.264459e-02 1.370107e-01 17 45104859 45104996 138 + 1.613 1.496 -0.398
ENSG00000136448 E033 1.3894374 0.0259550492 3.359726e-03 3.760586e-02 17 45104997 45105618 622 + 0.092 0.548 3.417
ENSG00000136448 E034 20.2056036 0.0007216573 8.129984e-02 2.930277e-01 17 45105619 45105643 25 + 1.380 1.266 -0.396
ENSG00000136448 E035 42.0438785 0.0003511899 6.785614e-02 2.628566e-01 17 45105644 45105877 234 + 1.674 1.591 -0.283
ENSG00000136448 E036 14.7857131 0.0110993460 9.570146e-01 9.897505e-01 17 45105878 45105945 68 + 1.202 1.195 -0.024
ENSG00000136448 E037 126.9170998 0.0001492964 2.187528e-02 1.342842e-01 17 45105946 45107778 1833 + 2.078 2.134 0.188
ENSG00000136448 E038 117.5930888 0.0001373516 2.320232e-07 1.241462e-05 17 45107779 45108677 899 + 2.002 2.135 0.447
ENSG00000136448 E039 23.6434895 0.0005965531 5.864190e-01 8.166048e-01 17 45108678 45109016 339 + 1.375 1.407 0.110

Help

Please Click HERE to learn more details about the results from DEXseq.