ENSG00000136527

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259043 ENSG00000136527 No_inf pgKDN_inf TRA2B protein_coding protein_coding 120.1462 92.77677 135.8919 2.530397 2.503034 0.5505746 40.279077 31.34919 42.84997 1.7557315 4.408220 0.4507427 0.3349833 0.337825 0.313975 -0.023850 8.663875e-01 1.754501e-11 FALSE FALSE
ENST00000382191 ENSG00000136527 No_inf pgKDN_inf TRA2B protein_coding protein_coding 120.1462 92.77677 135.8919 2.530397 2.503034 0.5505746 9.144322 0.00000 11.11203 0.0000000 1.976206 10.1192045 0.0686750 0.000000 0.081625 0.081625 1.754501e-11 1.754501e-11   TRUE
ENST00000456380 ENSG00000136527 No_inf pgKDN_inf TRA2B protein_coding nonsense_mediated_decay 120.1462 92.77677 135.8919 2.530397 2.503034 0.5505746 24.258185 22.15715 28.39450 0.6361802 1.802272 0.3576961 0.2060583 0.239150 0.209650 -0.029500 8.265014e-01 1.754501e-11 FALSE TRUE
ENST00000485530 ENSG00000136527 No_inf pgKDN_inf TRA2B protein_coding retained_intron 120.1462 92.77677 135.8919 2.530397 2.503034 0.5505746 21.562102 12.44836 28.24647 0.9430231 1.031745 1.1814669 0.1744917 0.133825 0.208000 0.074175 1.855217e-01 1.754501e-11 FALSE FALSE
ENST00000492417 ENSG00000136527 No_inf pgKDN_inf TRA2B protein_coding retained_intron 120.1462 92.77677 135.8919 2.530397 2.503034 0.5505746 13.969318 17.65835 10.23299 0.3773949 0.642964 -0.7865303 0.1242417 0.190925 0.075475 -0.115450 1.089808e-03 1.754501e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136527 E001 4.5635061 0.0035880992 2.036348e-01 4.862677e-01 3 185914558 185916743 2186 - 0.661 0.815 0.627
ENSG00000136527 E002 0.4746825 0.0572679478 5.493852e-02   3 185916744 185916748 5 - 0.291 0.000 -12.494
ENSG00000136527 E003 114.5401892 0.0032512668 8.478100e-01 9.460768e-01 3 185916749 185917154 406 - 2.058 2.067 0.031
ENSG00000136527 E004 102.2577892 0.0007516394 2.782579e-01 5.715860e-01 3 185917155 185917327 173 - 2.029 1.999 -0.102
ENSG00000136527 E005 31.5613456 0.0005169653 8.895135e-01 9.632594e-01 3 185917328 185917328 1 - 1.515 1.510 -0.015
ENSG00000136527 E006 30.6975728 0.0007035092 8.318643e-01 9.392783e-01 3 185917329 185917329 1 - 1.505 1.497 -0.029
ENSG00000136527 E007 198.9910055 0.0001287034 6.620612e-01 8.590375e-01 3 185917330 185917714 385 - 2.304 2.298 -0.020
ENSG00000136527 E008 26.4116377 0.0005421636 4.101250e-02 1.965680e-01 3 185917715 185917725 11 - 1.492 1.378 -0.395
ENSG00000136527 E009 52.4062282 0.0003274220 3.146796e-02 1.674421e-01 3 185918365 185918435 71 - 1.769 1.683 -0.290
ENSG00000136527 E010 26.4502955 0.0005086449 1.332384e-01 3.877034e-01 3 185918436 185918438 3 - 1.479 1.395 -0.287
ENSG00000136527 E011 34.3836260 0.0004025447 9.860046e-02 3.276058e-01 3 185919437 185919496 60 - 1.588 1.507 -0.275
ENSG00000136527 E012 45.6091094 0.0003118328 6.519955e-01 8.534423e-01 3 185921104 185921187 84 - 1.677 1.660 -0.057
ENSG00000136527 E013 48.6649149 0.0002865348 6.461343e-01 8.502474e-01 3 185922011 185922042 32 - 1.704 1.688 -0.056
ENSG00000136527 E014 66.3044951 0.0003031960 7.980144e-01 9.239247e-01 3 185922043 185922126 84 - 1.831 1.825 -0.022
ENSG00000136527 E015 9.0206864 0.1069255078 2.760216e-01 5.694213e-01 3 185922127 185923795 1669 - 0.885 1.090 0.759
ENSG00000136527 E016 108.8102490 0.0001506458 4.882430e-01 7.516383e-01 3 185923796 185923984 189 - 2.049 2.032 -0.056
ENSG00000136527 E017 0.0000000       3 185923985 185924008 24 -      
ENSG00000136527 E018 2.3602029 0.0080322572 9.083314e-02 3.130350e-01 3 185924009 185925084 1076 - 0.386 0.630 1.190
ENSG00000136527 E019 0.3802764 0.0324034156 9.692433e-02   3 185925085 185925229 145 - 0.000 0.244 11.613
ENSG00000136527 E020 0.1170040 0.0116656464 5.624025e-01   3 185925230 185925272 43 - 0.093 0.000 -10.847
ENSG00000136527 E021 0.8612261 0.0131798439 6.653153e-01 8.608045e-01 3 185925273 185925463 191 - 0.234 0.302 0.489
ENSG00000136527 E022 96.0731189 0.0001714073 6.692818e-03 6.113998e-02 3 185925464 185925626 163 - 2.025 1.946 -0.264
ENSG00000136527 E023 89.2858875 0.0001921003 3.594616e-04 6.743374e-03 3 185926601 185926726 126 - 2.007 1.898 -0.366
ENSG00000136527 E024 37.4656509 0.0004345920 3.509822e-03 3.884593e-02 3 185926727 185926734 8 - 1.650 1.510 -0.476
ENSG00000136527 E025 91.2612253 0.0001718635 8.669029e-41 7.924668e-38 3 185926735 185929073 2339 - 1.688 2.130 1.488
ENSG00000136527 E026 2.6118953 0.0067609660 3.909059e-02 1.914211e-01 3 185931515 185931576 62 - 0.386 0.678 1.396
ENSG00000136527 E027 30.0415500 0.0093123924 5.048888e-02 2.220556e-01 3 185931577 185931852 276 - 1.420 1.552 0.454
ENSG00000136527 E028 2.3269787 0.1439034967 9.615433e-01 9.916036e-01 3 185934429 185934505 77 - 0.530 0.513 -0.079
ENSG00000136527 E029 24.6985502 0.0041727346 6.798756e-07 3.297519e-05 3 185934506 185936237 1732 - 1.211 1.543 1.151
ENSG00000136527 E030 12.2734116 0.0011212444 4.044441e-04 7.374336e-03 3 185936238 185937420 1183 - 0.948 1.245 1.074
ENSG00000136527 E031 73.8237809 0.0002328285 1.999974e-05 6.181468e-04 3 185937825 185938103 279 - 1.941 1.796 -0.489

Help

Please Click HERE to learn more details about the results from DEXseq.