ENSG00000136643

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366960 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding protein_coding 11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 1.4655473 0.0000000 3.860695 0.0000000 1.2955998 8.596449 0.15666667 0.000000 0.42090 0.420900 0.20113826 0.02018474 FALSE TRUE
ENST00000490299 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding protein_coding_CDS_not_defined 11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 1.0083970 1.2790295 0.000000 0.4288407 0.0000000 -7.010141 0.14920833 0.239550 0.00000 -0.239550 0.02018474 0.02018474 FALSE TRUE
ENST00000491616 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding protein_coding_CDS_not_defined 11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 1.7873279 1.8940038 2.126984 0.3341746 0.6351852 0.166540 0.19995833 0.319900 0.14505 -0.174850 0.40566508 0.02018474 FALSE FALSE
ENST00000543354 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding protein_coding 11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 0.4870934 1.1515616 0.000000 0.7999522 0.0000000 -6.859922 0.08882500 0.217250 0.00000 -0.217250 0.40067863 0.02018474 FALSE TRUE
ENST00000615329 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding protein_coding 11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 0.6651863 0.4642284 0.000000 0.2863200 0.0000000 -5.567510 0.10710000 0.090475 0.00000 -0.090475 0.37472018 0.02018474 FALSE TRUE
MSTRG.2673.11 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding   11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 4.3601736 0.0000000 13.080521 0.0000000 9.2653201 10.354307 0.11891667 0.000000 0.35675 0.356750 0.76070844 0.02018474   FALSE
MSTRG.2673.8 ENSG00000136643 No_inf pgKDN_inf RPS6KC1 protein_coding   11.78606 6.177781 20.4796 1.46085 9.586864 1.727398 0.7904481 1.3889579 0.000000 1.3889579 0.0000000 -7.128209 0.07428333 0.132850 0.00000 -0.132850 0.73325959 0.02018474 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136643 E001 0.0000000       1 213051233 213051240 8 +      
ENSG00000136643 E002 0.0000000       1 213051241 213051254 14 +      
ENSG00000136643 E003 0.0000000       1 213051255 213051275 21 +      
ENSG00000136643 E004 0.2363338 0.0157521243 0.4791445908   1 213051276 213051372 97 + 0.140 0.000 -9.725
ENSG00000136643 E005 1.9222326 0.0088856852 0.2986499197 0.59163106 1 213051373 213051509 137 + 0.516 0.355 -0.851
ENSG00000136643 E006 1.4298050 0.0321705722 0.1312720237 0.38435912 1 213071006 213071041 36 + 0.462 0.213 -1.588
ENSG00000136643 E007 0.0000000       1 213072870 213072937 68 +      
ENSG00000136643 E008 0.0000000       1 213072938 213072986 49 +      
ENSG00000136643 E009 2.6260114 0.1609704692 0.1583610733 0.42532972 1 213077696 213077816 121 + 0.645 0.355 -1.434
ENSG00000136643 E010 0.1186381 0.0118611386 1.0000000000   1 213086320 213086357 38 + 0.075 0.000 -10.932
ENSG00000136643 E011 2.0321494 0.0121470387 0.0813164574 0.29304569 1 213104454 213104569 116 + 0.563 0.289 -1.488
ENSG00000136643 E012 0.0000000       1 213108169 213108185 17 +      
ENSG00000136643 E013 2.5337496 0.0058398438 0.3999049518 0.68356333 1 213117317 213117410 94 + 0.585 0.462 -0.588
ENSG00000136643 E014 0.0000000       1 213125766 213125843 78 +      
ENSG00000136643 E015 5.7441408 0.0179443205 0.2148032066 0.50033238 1 213129527 213129889 363 + 0.759 0.900 0.550
ENSG00000136643 E016 2.3302081 0.2430286527 0.4531547870 0.72594678 1 213167858 213167973 116 + 0.433 0.618 0.884
ENSG00000136643 E017 2.6725583 0.4174062098 0.9239442128 0.97687739 1 213176400 213176492 93 + 0.540 0.584 0.203
ENSG00000136643 E018 0.0000000       1 213176493 213176704 212 +      
ENSG00000136643 E019 0.2363338 0.0157521243 0.4791445908   1 213205335 213205389 55 + 0.140 0.000 -11.814
ENSG00000136643 E020 2.4068681 0.0058985621 0.2423904376 0.53208879 1 213230497 213230544 48 + 0.585 0.411 -0.851
ENSG00000136643 E021 3.1406683 0.0046630679 0.4841799904 0.74839999 1 213232123 213232255 133 + 0.645 0.547 -0.436
ENSG00000136643 E022 32.5510295 0.0028587879 0.0016753634 0.02225592 1 213240702 213242059 1358 + 1.573 1.409 -0.565
ENSG00000136643 E023 9.3520029 0.0144353797 0.7746913254 0.91347184 1 213242060 213242297 238 + 0.996 1.020 0.086
ENSG00000136643 E024 2.9332930 0.0056071406 0.3971588438 0.68146105 1 213242298 213242568 271 + 0.540 0.651 0.493
ENSG00000136643 E025 5.6902126 0.0025411647 0.6365944525 0.84488564 1 213242569 213242658 90 + 0.838 0.782 -0.220
ENSG00000136643 E026 5.8164676 0.0025546891 0.7826486886 0.91642303 1 213261558 213261640 83 + 0.838 0.804 -0.133
ENSG00000136643 E027 5.6239153 0.0034189473 0.1439836988 0.40408038 1 213262721 213262816 96 + 0.745 0.900 0.609
ENSG00000136643 E028 46.4933421 0.0004324095 0.0002253448 0.00461593 1 213272524 213274774 2251 + 1.611 1.740 0.438

Help

Please Click HERE to learn more details about the results from DEXseq.