ENSG00000136718

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259239 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding protein_coding 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 5.959162 4.1755236 6.740580 2.5810228 4.0239316 0.6896034 0.17525833 0.185775 0.169600 -0.016175 1.00000000 0.02236985 FALSE TRUE
ENST00000409649 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding protein_coding 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 3.874657 2.0645008 3.749344 2.0645008 3.7493440 0.8577167 0.12370000 0.097025 0.112350 0.015325 1.00000000 0.02236985 FALSE TRUE
ENST00000409935 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding protein_coding 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 1.843851 1.3620735 2.363376 0.4247156 0.7568674 0.7905832 0.05856667 0.055525 0.072050 0.016525 0.95326667 0.02236985 FALSE TRUE
ENST00000456713 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding nonsense_mediated_decay 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 1.047379 3.1421381 0.000000 3.1421381 0.0000000 -8.3001869 0.03504167 0.105125 0.000000 -0.105125 0.83336508 0.02236985   FALSE
ENST00000460766 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding retained_intron 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 3.358998 2.0205070 5.256441 2.0205070 3.2201444 1.3749883 0.10061667 0.067600 0.160850 0.093250 0.82830574 0.02236985 FALSE TRUE
ENST00000462357 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding retained_intron 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 1.490499 2.3217973 1.251921 0.9063227 1.2519208 -0.8858210 0.04798333 0.088125 0.031725 -0.056400 0.40544110 0.02236985 FALSE FALSE
ENST00000473689 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding retained_intron 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 4.249466 0.8640291 2.885764 0.8640291 2.8857645 1.7281911 0.12509167 0.043250 0.086475 0.043225 1.00000000 0.02236985 TRUE TRUE
ENST00000477375 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding retained_intron 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 3.688554 0.0000000 8.191951 0.0000000 4.2926527 9.6798234 0.09486667 0.000000 0.217725 0.217725 0.02236985 0.02236985   FALSE
ENST00000490895 ENSG00000136718 No_inf pgKDN_inf IMP4 protein_coding retained_intron 32.98161 24.96547 35.59808 2.528242 2.568053 0.5116928 4.857547 4.5160918 2.852851 1.9342190 1.6528591 -0.6608131 0.15124167 0.186550 0.083950 -0.102600 0.77007588 0.02236985 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136718 E001 1.8296308 0.0077906048 0.747891072 0.90057518 2 130342877 130342893 17 + 0.429 0.476 0.244
ENSG00000136718 E002 2.4482247 0.0058206600 0.505167502 0.76412677 2 130342894 130342895 2 + 0.492 0.585 0.437
ENSG00000136718 E003 2.4482247 0.0058206600 0.505167502 0.76412677 2 130342896 130342896 1 + 0.492 0.585 0.437
ENSG00000136718 E004 3.1745992 0.0045301125 0.711763003 0.88347977 2 130342897 130342909 13 + 0.596 0.645 0.214
ENSG00000136718 E005 3.1745992 0.0045301125 0.711763003 0.88347977 2 130342910 130342911 2 + 0.596 0.645 0.214
ENSG00000136718 E006 5.4933846 0.0026345826 0.577502307 0.81120454 2 130342912 130342917 6 + 0.782 0.844 0.244
ENSG00000136718 E007 6.1979151 0.0042360691 0.849403273 0.94644484 2 130342918 130342921 4 + 0.864 0.844 -0.078
ENSG00000136718 E008 6.6888997 0.0024612953 0.916918194 0.97388814 2 130342922 130342923 2 + 0.888 0.878 -0.040
ENSG00000136718 E009 7.1720804 0.0020563006 0.774875940 0.91353184 2 130342924 130342935 12 + 0.922 0.894 -0.108
ENSG00000136718 E010 1.7753702 0.0078270881 0.001913649 0.02473892 2 130342936 130342962 27 + 0.596 0.109 -3.371
ENSG00000136718 E011 1.5748503 0.0098857477 0.768426373 0.91048371 2 130342963 130343085 123 + 0.429 0.385 -0.241
ENSG00000136718 E012 17.7885895 0.0101165784 0.086878177 0.30552783 2 130343086 130343194 109 + 1.326 1.191 -0.475
ENSG00000136718 E013 0.2545247 0.2215084611 0.196116857   2 130343270 130343347 78 + 0.000 0.196 11.368
ENSG00000136718 E014 17.2994644 0.0014054635 0.028422011 0.15780448 2 130344629 130344712 84 + 1.322 1.166 -0.548
ENSG00000136718 E015 0.3813786 0.0293733457 0.058156116   2 130344713 130344725 13 + 0.000 0.268 12.389
ENSG00000136718 E016 2.2256434 0.0309241521 0.133263289 0.38775476 2 130344726 130345020 295 + 0.393 0.616 1.089
ENSG00000136718 E017 24.3616232 0.0006156374 0.996948442 1.00000000 2 130345376 130345485 110 + 1.401 1.401 0.001
ENSG00000136718 E018 1.6149785 0.0082766168 0.054526567 0.23256907 2 130345486 130345566 81 + 0.265 0.552 1.607
ENSG00000136718 E019 25.2532136 0.0007430413 0.669167075 0.86233223 2 130345567 130345632 66 + 1.405 1.430 0.087
ENSG00000136718 E020 17.0875441 0.0008460645 0.550085071 0.79466024 2 130345633 130345641 9 + 1.236 1.277 0.147
ENSG00000136718 E021 25.4549538 0.0006112182 0.902756939 0.96886466 2 130345642 130345699 58 + 1.423 1.416 -0.023
ENSG00000136718 E022 0.1187032 0.0118811564 0.732437864   2 130345700 130345778 79 + 0.083 0.000 -11.219
ENSG00000136718 E023 34.6804460 0.0004681305 0.606262695 0.82856213 2 130345779 130345933 155 + 1.560 1.536 -0.085
ENSG00000136718 E024 0.7374881 0.4453270770 0.665883375 0.86103462 2 130345934 130345944 11 + 0.213 0.268 0.435
ENSG00000136718 E025 1.3639161 0.1599309201 0.253958893 0.54556755 2 130345945 130346017 73 + 0.265 0.476 1.244
ENSG00000136718 E026 23.6341845 0.0070356796 0.942493765 0.98400647 2 130346018 130346112 95 + 1.390 1.387 -0.013
ENSG00000136718 E027 0.6167687 0.0162621456 0.437420791 0.71365034 2 130346113 130346200 88 + 0.153 0.268 1.022
ENSG00000136718 E028 18.3417747 0.0008462403 0.171901601 0.44458334 2 130346201 130346249 49 + 1.241 1.333 0.321
ENSG00000136718 E029 14.7259731 0.0009444020 0.788588485 0.91890468 2 130346250 130346274 25 + 1.202 1.183 -0.069
ENSG00000136718 E030 0.1268540 0.0126053431 0.393718506   2 130346275 130346341 67 + 0.000 0.109 10.967
ENSG00000136718 E031 98.0916517 0.0002780046 0.756823325 0.90428724 2 130346356 130347967 1612 + 1.989 1.998 0.029

Help

Please Click HERE to learn more details about the results from DEXseq.