ENSG00000136731

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259253 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding protein_coding 22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 5.1628525 3.7944198 4.044100 0.8870752 1.539037 0.09170508 0.23151667 0.174850 0.180200 0.005350 9.825913e-01 6.657308e-13 FALSE TRUE
ENST00000418197 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding protein_coding 22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 2.6904073 7.0226157 0.000000 0.3114113 0.000000 -9.45791758 0.12230833 0.321475 0.000000 -0.321475 6.657308e-13 6.657308e-13 FALSE FALSE
MSTRG.16970.11 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding   22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 6.4394762 6.3559542 8.762051 0.9591201 3.066302 0.46253737 0.28821667 0.288925 0.391550 0.102625 9.389397e-01 6.657308e-13 FALSE TRUE
MSTRG.16970.6 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding   22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 0.6819655 0.0000000 1.830594 0.0000000 1.830594 7.52402800 0.03056667 0.000000 0.082000 0.082000 8.462210e-01 6.657308e-13 FALSE TRUE
MSTRG.16970.7 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding   22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 1.7165187 0.8078249 2.650039 0.8078249 1.199321 1.70158338 0.07560000 0.036175 0.117525 0.081350 4.619282e-01 6.657308e-13 FALSE TRUE
MSTRG.16970.9 ENSG00000136731 No_inf pgKDN_inf UGGT1 protein_coding   22.30359 21.84493 22.44226 0.5981853 0.08740093 0.03890188 5.1387249 3.6844326 4.518006 0.6111700 3.341721 0.29352302 0.23071667 0.170825 0.200175 0.029350 8.100224e-01 6.657308e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136731 E001 0.3719991 0.0167387637 5.315347e-01   2 128091200 128091207 8 + 0.091 0.180 1.130
ENSG00000136731 E002 0.3719991 0.0167387637 5.315347e-01   2 128091208 128091210 3 + 0.091 0.180 1.130
ENSG00000136731 E003 0.6257071 0.0172815552 1.466154e-01 4.076740e-01 2 128091211 128091212 2 + 0.091 0.306 2.130
ENSG00000136731 E004 1.3435198 0.0332970261 8.754781e-01 9.574998e-01 2 128091213 128091235 23 + 0.381 0.358 -0.133
ENSG00000136731 E005 3.7851943 0.0038329628 7.686788e-01 9.105427e-01 2 128091236 128091382 147 + 0.697 0.661 -0.150
ENSG00000136731 E006 1.5902672 0.0218632205 9.086419e-01 9.710257e-01 2 128091383 128091415 33 + 0.421 0.404 -0.093
ENSG00000136731 E007 0.4696501 0.2100000084 9.040165e-02   2 128091416 128091596 181 + 0.287 0.000 -12.054
ENSG00000136731 E008 1.8155249 0.0075193138 2.616154e-01 5.543252e-01 2 128097429 128097430 2 + 0.524 0.358 -0.870
ENSG00000136731 E009 5.6974843 0.0024906619 1.105486e-01 3.489597e-01 2 128097431 128097564 134 + 0.904 0.729 -0.689
ENSG00000136731 E010 0.0000000       2 128103079 128103145 67 +      
ENSG00000136731 E011 4.5115661 0.0207394909 6.067752e-01 8.288396e-01 2 128103932 128104014 83 + 0.772 0.707 -0.262
ENSG00000136731 E012 7.1728714 0.0020510905 2.746666e-01 5.681520e-01 2 128107938 128108068 131 + 0.963 0.854 -0.414
ENSG00000136731 E013 8.3113518 0.0040459212 9.122064e-01 9.720229e-01 2 128109634 128109746 113 + 0.963 0.975 0.045
ENSG00000136731 E014 7.0775591 0.0022596366 6.498438e-01 8.525377e-01 2 128113084 128113258 175 + 0.929 0.884 -0.169
ENSG00000136731 E015 4.1004831 0.0034687681 3.049418e-02 1.643256e-01 2 128115124 128115220 97 + 0.821 0.552 -1.133
ENSG00000136731 E016 3.9546282 0.0036750633 1.726336e-03 2.278712e-02 2 128116265 128116343 79 + 0.850 0.446 -1.763
ENSG00000136731 E017 4.8096747 0.0027723170 3.330682e-03 3.736210e-02 2 128120356 128120456 101 + 0.904 0.552 -1.455
ENSG00000136731 E018 5.2748958 0.0047087927 4.674188e-01 7.358107e-01 2 128121199 128121298 100 + 0.754 0.838 0.332
ENSG00000136731 E019 5.2608534 0.0040776389 8.968708e-01 9.659944e-01 2 128123186 128123246 61 + 0.789 0.805 0.063
ENSG00000136731 E020 6.0460673 0.0390194419 6.760876e-02 2.623344e-01 2 128127361 128127452 92 + 0.952 0.707 -0.957
ENSG00000136731 E021 9.3364404 0.0016781191 4.461091e-02 2.064221e-01 2 128129029 128129179 151 + 1.096 0.912 -0.677
ENSG00000136731 E022 7.2308566 0.0018796383 2.271487e-03 2.812068e-02 2 128133141 128133260 120 + 1.044 0.729 -1.209
ENSG00000136731 E023 5.5546469 0.0024770762 1.762524e-02 1.166953e-01 2 128134876 128134961 86 + 0.929 0.661 -1.063
ENSG00000136731 E024 0.0000000       2 128136052 128136083 32 +      
ENSG00000136731 E025 7.2604844 0.0022116556 2.480251e-02 1.447883e-01 2 128138717 128138852 136 + 1.015 0.787 -0.870
ENSG00000136731 E026 13.5836802 0.0114580374 9.998964e-01 1.000000e+00 2 128143094 128143225 132 + 1.164 1.163 0.000
ENSG00000136731 E027 0.0000000       2 128145652 128145802 151 +      
ENSG00000136731 E028 14.9093548 0.0009316683 8.073372e-01 9.288700e-01 2 128145803 128145967 165 + 1.210 1.193 -0.059
ENSG00000136731 E029 9.8108492 0.0016132848 1.705735e-02 1.140837e-01 2 128152784 128152904 121 + 1.127 0.912 -0.791
ENSG00000136731 E030 0.1170040 0.0116318156 5.864610e-01   2 128153892 128153947 56 + 0.091 0.000 -10.726
ENSG00000136731 E031 7.0662572 0.0028810198 3.323002e-01 6.244578e-01 2 128155489 128155587 99 + 0.952 0.854 -0.373
ENSG00000136731 E032 4.0064329 0.0421305126 4.039844e-01 6.868143e-01 2 128156392 128156415 24 + 0.754 0.636 -0.491
ENSG00000136731 E033 10.2480111 0.0013727244 2.569362e-04 5.138153e-03 2 128157252 128157346 95 + 1.184 0.854 -1.216
ENSG00000136731 E034 18.7694706 0.0007278976 6.341478e-04 1.048502e-02 2 128159514 128159720 207 + 1.396 1.163 -0.814
ENSG00000136731 E035 10.2156115 0.0025102945 1.226837e-01 3.706902e-01 2 128160460 128160539 80 + 1.112 0.975 -0.498
ENSG00000136731 E036 9.8515447 0.0024700678 1.394824e-01 3.971469e-01 2 128160540 128160591 52 + 1.096 0.963 -0.485
ENSG00000136731 E037 18.3456289 0.0008882186 3.161552e-02 1.679787e-01 2 128161138 128161268 131 + 1.353 1.207 -0.511
ENSG00000136731 E038 13.0255086 0.0010540102 2.339661e-01 5.230127e-01 2 128164730 128164825 96 + 1.191 1.098 -0.332
ENSG00000136731 E039 16.2388327 0.0009835955 6.522973e-01 8.534955e-01 2 128170288 128170390 103 + 1.252 1.221 -0.109
ENSG00000136731 E040 14.0214791 0.0011040921 3.534242e-01 6.431466e-01 2 128171205 128171284 80 + 1.210 1.140 -0.248
ENSG00000136731 E041 0.0000000       2 128171285 128171390 106 +      
ENSG00000136731 E042 21.4139380 0.0037442120 8.428809e-02 2.997886e-01 2 128172573 128172762 190 + 1.404 1.289 -0.400
ENSG00000136731 E043 20.1296167 0.0006661379 4.436362e-01 7.184228e-01 2 128173781 128173939 159 + 1.348 1.300 -0.168
ENSG00000136731 E044 12.5984434 0.0030434334 9.594159e-01 9.904193e-01 2 128174773 128174858 86 + 1.135 1.132 -0.010
ENSG00000136731 E045 13.7602593 0.0043348923 1.826452e-01 4.591372e-01 2 128176814 128176898 85 + 1.112 1.221 0.388
ENSG00000136731 E046 16.2849406 0.0360118012 7.570104e-01 9.043624e-01 2 128177832 128177920 89 + 1.222 1.253 0.108
ENSG00000136731 E047 18.7007140 0.0163315130 8.802568e-01 9.595929e-01 2 128178468 128178569 102 + 1.300 1.289 -0.040
ENSG00000136731 E048 15.2832140 0.0009009512 1.796913e-02 1.181743e-01 2 128179786 128179870 85 + 1.290 1.115 -0.619
ENSG00000136731 E049 28.2591755 0.0005006420 7.901275e-04 1.248600e-02 2 128180890 128181072 183 + 1.549 1.362 -0.643
ENSG00000136731 E050 30.8792892 0.0004549923 1.394672e-02 9.977483e-02 2 128182130 128182290 161 + 1.563 1.433 -0.445
ENSG00000136731 E051 28.3047752 0.0007421804 3.960293e-01 6.808659e-01 2 128183675 128183789 115 + 1.442 1.491 0.168
ENSG00000136731 E052 31.7455331 0.0005595702 3.155292e-01 6.083813e-01 2 128186683 128186799 117 + 1.487 1.542 0.186
ENSG00000136731 E053 0.0000000       2 128187237 128187319 83 +      
ENSG00000136731 E054 42.4478863 0.0063751045 8.601773e-01 9.515301e-01 2 128187449 128187614 166 + 1.632 1.644 0.038
ENSG00000136731 E055 664.5095219 0.0001246580 2.306723e-19 5.896246e-17 2 128189717 128195677 5961 + 2.784 2.859 0.251

Help

Please Click HERE to learn more details about the results from DEXseq.