ENSG00000136819

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372447 ENSG00000136819 No_inf pgKDN_inf C9orf78 protein_coding protein_coding 56.48703 46.81656 63.9261 3.098772 1.451542 0.4493037 42.34134 41.499529 45.15261 0.9610952 0.680045 0.1216863 0.7671083 0.900400 0.707600 -0.1928 0.02444560 0.01823791 FALSE TRUE
ENST00000461539 ENSG00000136819 No_inf pgKDN_inf C9orf78 protein_coding protein_coding_CDS_not_defined 56.48703 46.81656 63.9261 3.098772 1.451542 0.4493037 12.43031 3.364914 16.61014 3.3649144 2.326366 2.3000101 0.2022917 0.059975 0.258375 0.1984 0.01823791 0.01823791 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136819 E001 133.4663753 0.0001459760 3.170126e-01 0.609723571 9 129827290 129827967 678 - 2.115 2.141 0.088
ENSG00000136819 E002 72.2568545 0.0002116011 3.505727e-01 0.640802727 9 129827968 129828252 285 - 1.879 1.851 -0.095
ENSG00000136819 E003 0.0000000       9 129828428 129828441 14 -      
ENSG00000136819 E004 1.7339948 0.0079932322 2.723270e-01 0.566067902 9 129828442 129829204 763 - 0.344 0.509 0.885
ENSG00000136819 E005 35.0619870 0.0004238548 5.200867e-01 0.774596781 9 129829205 129829278 74 - 1.539 1.573 0.118
ENSG00000136819 E006 24.5514555 0.0005656133 3.217604e-01 0.614795340 9 129829279 129829303 25 - 1.375 1.436 0.211
ENSG00000136819 E007 53.2663511 0.0002944607 1.344729e-01 0.389865169 9 129829405 129829541 137 - 1.701 1.764 0.210
ENSG00000136819 E008 1.7786203 0.0658901448 9.104247e-05 0.002199948 9 129829542 129830685 1144 - 0.000 0.650 13.600
ENSG00000136819 E009 34.0437120 0.0004580578 1.373425e-01 0.394494961 9 129830871 129830934 64 - 1.579 1.508 -0.243
ENSG00000136819 E010 33.8713375 0.0004042030 3.036192e-02 0.163967148 9 129830935 129830961 27 - 1.593 1.488 -0.360
ENSG00000136819 E011 62.8121294 0.0003023075 1.797121e-01 0.454957271 9 129830962 129831068 107 - 1.827 1.782 -0.154
ENSG00000136819 E012 0.2543986 0.0159531607 2.359520e-01   9 129831410 129831732 323 - 0.000 0.175 11.024
ENSG00000136819 E013 46.0376386 0.0003757939 9.338867e-01 0.981013846 9 129831896 129831973 78 - 1.669 1.675 0.022
ENSG00000136819 E014 33.9460737 0.0005685433 2.906693e-01 0.584176338 9 129833447 129833517 71 - 1.568 1.518 -0.171
ENSG00000136819 E015 0.4999558 0.0156791881 3.101743e-01 0.603473311 9 129833518 129833657 140 - 0.094 0.242 1.622
ENSG00000136819 E016 14.9165110 0.0022515875 7.979097e-01 0.923843139 9 129833658 129833709 52 - 1.210 1.194 -0.057
ENSG00000136819 E017 3.5097835 0.0040438374 3.806590e-04 0.007023764 9 129833710 129834547 838 - 0.344 0.826 2.239
ENSG00000136819 E018 0.0000000       9 129834707 129834711 5 -      
ENSG00000136819 E019 0.0000000       9 129834712 129834766 55 -      
ENSG00000136819 E020 7.2560207 0.0176325158 5.176759e-01 0.773138050 9 129835139 129835281 143 - 0.876 0.951 0.282
ENSG00000136819 E021 0.1186381 0.0117901586 5.480536e-01   9 129835788 129835863 76 - 0.094 0.000 -10.300

Help

Please Click HERE to learn more details about the results from DEXseq.