ENSG00000136875

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374198 ENSG00000136875 No_inf pgKDN_inf PRPF4 protein_coding protein_coding 17.80173 9.763148 21.44217 0.3962429 0.250029 1.134229 13.277262 9.132712 13.83385 0.3264492 1.567019 0.5985513 0.7802750 0.9366 0.643850 -0.292750 0.0086716610 0.0003665947 FALSE TRUE
ENST00000374199 ENSG00000136875 No_inf pgKDN_inf PRPF4 protein_coding protein_coding 17.80173 9.763148 21.44217 0.3962429 0.250029 1.134229 3.740872 0.000000 6.30059 0.0000000 1.835198 9.3016310 0.1721167 0.0000 0.295025 0.295025 0.0003665947 0.0003665947 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136875 E001 0.0000000       9 113275642 113275657 16 +      
ENSG00000136875 E002 0.4726676 0.0662093473 0.1895595318   9 113275658 113275676 19 + 0.230 0.000 -10.111
ENSG00000136875 E003 0.8453610 0.1088506402 0.7886705860 0.91890468 9 113275677 113275678 2 + 0.273 0.227 -0.354
ENSG00000136875 E004 1.0816298 0.0330496013 0.4557766632 0.72819630 9 113275679 113275684 6 + 0.347 0.227 -0.839
ENSG00000136875 E005 9.8661569 0.0014210458 0.1060927053 0.34102783 9 113275685 113275770 86 + 1.067 0.913 -0.570
ENSG00000136875 E006 0.8259403 0.0129789945 0.0392942344 0.19195535 9 113276545 113276547 3 + 0.347 0.000 -13.168
ENSG00000136875 E007 21.8687748 0.0007509217 0.3962886154 0.68098611 9 113276548 113276725 178 + 1.359 1.305 -0.190
ENSG00000136875 E008 20.5390986 0.0008259297 0.4504621590 0.72376150 9 113278945 113279095 151 + 1.332 1.282 -0.174
ENSG00000136875 E009 8.9687643 0.0016469013 0.6367837071 0.84489883 9 113279096 113279131 36 + 0.965 1.011 0.169
ENSG00000136875 E010 14.7513929 0.0009521472 0.0035903619 0.03946252 9 113282646 113282733 88 + 1.250 1.011 -0.861
ENSG00000136875 E011 0.2455571 0.0163533648 0.6018128956   9 113282734 113283131 398 + 0.070 0.128 0.969
ENSG00000136875 E012 16.5998881 0.0008523614 0.0468732009 0.21266688 9 113283132 113283211 80 + 1.275 1.125 -0.534
ENSG00000136875 E013 18.5660029 0.0113773645 0.3432024338 0.63442428 9 113283389 113283482 94 + 1.246 1.319 0.257
ENSG00000136875 E014 8.8337886 0.0377346611 0.9213831575 0.97546088 9 113284295 113284314 20 + 0.973 0.981 0.028
ENSG00000136875 E015 11.7305583 0.0046505373 0.7013503496 0.87832052 9 113284315 113284389 75 + 1.099 1.065 -0.121
ENSG00000136875 E016 0.6168947 0.0143306698 0.2367682221 0.52565996 9 113286193 113286231 39 + 0.130 0.307 1.554
ENSG00000136875 E017 11.9350188 0.0013553045 0.2335092974 0.52242463 9 113286232 113286290 59 + 1.128 1.025 -0.374
ENSG00000136875 E018 19.5484424 0.0169432938 0.4471942802 0.72134754 9 113286705 113286828 124 + 1.317 1.250 -0.236
ENSG00000136875 E019 15.7530010 0.0017303687 0.5809391086 0.81327856 9 113288175 113288264 90 + 1.191 1.233 0.148
ENSG00000136875 E020 18.5670706 0.0007643019 0.0009464483 0.01438313 9 113290466 113290588 123 + 1.181 1.403 0.779
ENSG00000136875 E021 20.8490850 0.0007340589 0.5401268839 0.78826722 9 113290700 113290807 108 + 1.306 1.347 0.142
ENSG00000136875 E022 22.0845219 0.0006545790 0.3134216115 0.60658391 9 113290898 113291016 119 + 1.321 1.385 0.223
ENSG00000136875 E023 163.6484802 0.0024584396 0.2764936982 0.57004630 9 113291467 113294009 2543 + 2.188 2.214 0.086

Help

Please Click HERE to learn more details about the results from DEXseq.