ENSG00000136877

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373225 ENSG00000136877 No_inf pgKDN_inf FPGS protein_coding protein_coding 56.68316 47.73144 60.3279 2.801093 2.678696 0.3378224 7.800539 8.678141 7.133959 1.659284 1.5662368 -0.2823238 0.1430167 0.182725 0.122000 -0.060725 0.7418391 0.0156405 FALSE TRUE
ENST00000373247 ENSG00000136877 No_inf pgKDN_inf FPGS protein_coding protein_coding 56.68316 47.73144 60.3279 2.801093 2.678696 0.3378224 15.508782 3.613818 19.549152 3.613818 3.5354854 2.4322613 0.2634667 0.086575 0.322025 0.235450 0.0156405 0.0156405 FALSE TRUE
ENST00000475270 ENSG00000136877 No_inf pgKDN_inf FPGS protein_coding protein_coding_CDS_not_defined 56.68316 47.73144 60.3279 2.801093 2.678696 0.3378224 13.093847 11.830763 12.947745 1.223338 1.9365146 0.1300526 0.2312833 0.246225 0.214100 -0.032125 0.8429271 0.0156405 FALSE FALSE
ENST00000479147 ENSG00000136877 No_inf pgKDN_inf FPGS protein_coding protein_coding_CDS_not_defined 56.68316 47.73144 60.3279 2.801093 2.678696 0.3378224 3.903826 3.716456 4.461681 1.309691 0.6812382 0.2630130 0.0689500 0.075325 0.074200 -0.001125 0.9749917 0.0156405 FALSE FALSE
ENST00000630236 ENSG00000136877 No_inf pgKDN_inf FPGS protein_coding protein_coding 56.68316 47.73144 60.3279 2.801093 2.678696 0.3378224 2.397429 4.435178 1.223318 2.680850 0.7678668 -1.8496970 0.0455000 0.095000 0.019300 -0.075700 0.8927873 0.0156405 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136877 E001 3.8265786 0.0039205331 0.0517078812 0.2256868873 9 127794597 127794681 85 + 0.554 0.799 1.036
ENSG00000136877 E002 5.4102448 0.0254791687 0.2146571558 0.5001865999 9 127794682 127794812 131 + 0.724 0.886 0.636
ENSG00000136877 E003 0.3706473 0.0164772750 0.4381107898   9 127802858 127802881 24 + 0.085 0.192 1.373
ENSG00000136877 E004 1.2114452 0.1597893657 0.8975481331 0.9662154650 9 127802882 127802892 11 + 0.360 0.325 -0.210
ENSG00000136877 E005 4.2130468 0.0195627102 0.0875014756 0.3065677916 9 127802893 127802910 18 + 0.805 0.578 -0.948
ENSG00000136877 E006 5.0600759 0.0028368562 0.0456960998 0.2093143468 9 127802911 127802916 6 + 0.872 0.638 -0.949
ENSG00000136877 E007 5.3130899 0.0026807555 0.1106166445 0.3490725005 9 127802917 127802917 1 + 0.872 0.690 -0.726
ENSG00000136877 E008 7.1090079 0.0027167270 0.0202740718 0.1280314135 9 127802918 127802931 14 + 1.001 0.759 -0.932
ENSG00000136877 E009 12.6811654 0.0011238375 0.0104020393 0.0823944176 9 127802932 127803023 92 + 1.217 1.008 -0.752
ENSG00000136877 E010 8.2894381 0.0028101245 0.8670079326 0.9541934832 9 127803024 127803062 39 + 0.973 0.958 -0.054
ENSG00000136877 E011 0.5086410 0.2218691298 0.0474425052 0.2140687757 9 127803063 127803156 94 + 0.000 0.325 11.537
ENSG00000136877 E012 0.9966669 0.0120311432 0.0751977396 0.2799361464 9 127803208 127803251 44 + 0.155 0.427 1.958
ENSG00000136877 E013 3.9331122 0.0043254353 0.1595666343 0.4269729537 9 127803252 127803323 72 + 0.603 0.779 0.736
ENSG00000136877 E014 5.4920974 0.0028779975 0.6905286845 0.8729367633 9 127803324 127803404 81 + 0.790 0.836 0.181
ENSG00000136877 E015 9.2630019 0.0014421456 0.9640633196 0.9924265265 9 127804285 127804285 1 + 1.011 1.008 -0.009
ENSG00000136877 E016 30.2515968 0.0005050819 0.8272155555 0.9374821804 9 127804286 127804413 128 + 1.487 1.500 0.046
ENSG00000136877 E017 23.8888749 0.0005811406 0.9306323877 0.9797720984 9 127804499 127804552 54 + 1.396 1.392 -0.012
ENSG00000136877 E018 23.6276745 0.0005607859 0.6902167453 0.8727995137 9 127804636 127804700 65 + 1.399 1.377 -0.077
ENSG00000136877 E019 1.8534859 0.1055274643 0.2655174743 0.5588456375 9 127804701 127804857 157 + 0.360 0.545 0.957
ENSG00000136877 E020 5.1262110 0.0073670570 0.0000134702 0.0004411061 9 127806497 127806972 476 + 0.468 0.996 2.203
ENSG00000136877 E021 14.7067227 0.0014034843 0.2844222530 0.5782051776 9 127806973 127806991 19 + 1.228 1.149 -0.282
ENSG00000136877 E022 26.5983035 0.0006165154 0.8081298529 0.9291769382 9 127806992 127807087 96 + 1.432 1.447 0.054
ENSG00000136877 E023 22.0567180 0.0015442426 0.0678370763 0.2628205499 9 127807209 127807286 78 + 1.304 1.421 0.405
ENSG00000136877 E024 19.9226998 0.0011848528 0.1749034627 0.4487319645 9 127807421 127807482 62 + 1.356 1.268 -0.308
ENSG00000136877 E025 21.9033459 0.0007376796 0.4866634017 0.7502344912 9 127807586 127807672 87 + 1.377 1.335 -0.145
ENSG00000136877 E026 14.8896561 0.0009807177 0.7546055280 0.9034762480 9 127807673 127807688 16 + 1.188 1.213 0.088
ENSG00000136877 E027 2.4326352 0.0060553121 0.7433811304 0.8985145867 9 127807689 127807775 87 + 0.554 0.509 -0.212
ENSG00000136877 E028 1.2272352 0.2319388601 0.7524472269 0.9024592739 9 127807776 127807849 74 + 0.317 0.379 0.373
ENSG00000136877 E029 1.6137474 0.0189011880 0.0701760149 0.2680997321 9 127808147 127808233 87 + 0.270 0.545 1.543
ENSG00000136877 E030 16.7125758 0.0008402429 0.8414156001 0.9430583109 9 127808234 127808263 30 + 1.239 1.255 0.056
ENSG00000136877 E031 20.3536079 0.0006477952 0.8829165697 0.9605624231 9 127808264 127808311 48 + 1.331 1.323 -0.027
ENSG00000136877 E032 25.5164691 0.0005758264 0.1707226763 0.4430276656 9 127808558 127808705 148 + 1.455 1.377 -0.269
ENSG00000136877 E033 1.1041350 0.0115322115 0.4798560215 0.7454408493 9 127808722 127808799 78 + 0.270 0.379 0.695
ENSG00000136877 E034 18.8896898 0.0007628282 0.7819113449 0.9160998423 9 127808800 127808889 90 + 1.304 1.287 -0.058
ENSG00000136877 E035 28.8942771 0.0054072629 0.9536795232 0.9885787316 9 127809684 127809834 151 + 1.475 1.473 -0.007
ENSG00000136877 E036 0.2537079 0.2436679327 0.2130652420   9 127809994 127810030 37 + 0.000 0.192 10.549
ENSG00000136877 E037 24.0228811 0.0006834789 0.7783523766 0.9148664358 9 127810031 127810106 76 + 1.388 1.407 0.064
ENSG00000136877 E038 24.8028700 0.0007222182 0.2992168805 0.5920808301 9 127810945 127811011 67 + 1.380 1.443 0.217
ENSG00000136877 E039 39.0775669 0.0003535471 0.3444773891 0.6357325656 9 127813195 127813323 129 + 1.580 1.626 0.156
ENSG00000136877 E040 133.0381979 0.0001582957 0.5895734941 0.8182300662 9 127813324 127814081 758 + 2.130 2.119 -0.036
ENSG00000136877 E041 1.4982269 0.0118524401 0.0300309726 0.1630420433 9 127814208 127814423 216 + 0.216 0.545 1.958

Help

Please Click HERE to learn more details about the results from DEXseq.