ENSG00000136986

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259512 ENSG00000136986 No_inf pgKDN_inf DERL1 protein_coding protein_coding 115.539 51.76078 146.6101 4.559806 3.880916 1.501873 58.808480 40.052841 69.0855175 0.7407022 2.1133220 0.7863274 0.57365833 0.793700 0.473050 -0.320650 1.092653e-02 9.966077e-10 FALSE TRUE
ENST00000405944 ENSG00000136986 No_inf pgKDN_inf DERL1 protein_coding protein_coding 115.539 51.76078 146.6101 4.559806 3.880916 1.501873 9.732055 0.000000 12.8774100 0.0000000 2.0836886 10.3317466 0.06623333 0.000000 0.088225 0.088225 9.966077e-10 9.966077e-10 FALSE TRUE
ENST00000419562 ENSG00000136986 No_inf pgKDN_inf DERL1 protein_coding protein_coding 115.539 51.76078 146.6101 4.559806 3.880916 1.501873 9.420901 3.658493 12.5298335 2.1700197 4.6777777 1.7732589 0.07588333 0.063275 0.083575 0.020300 8.478360e-01 9.966077e-10 FALSE TRUE
ENST00000523036 ENSG00000136986 No_inf pgKDN_inf DERL1 protein_coding protein_coding 115.539 51.76078 146.6101 4.559806 3.880916 1.501873 35.247658 2.989797 51.2505368 2.9897968 2.4858726 4.0949119 0.24788333 0.047125 0.349250 0.302125 2.213332e-02 9.966077e-10 FALSE TRUE
MSTRG.28162.2 ENSG00000136986 No_inf pgKDN_inf DERL1 protein_coding   115.539 51.76078 146.6101 4.559806 3.880916 1.501873 1.328666 3.740039 0.2459602 0.9390721 0.2459602 -3.8729140 0.02377500 0.069725 0.001600 -0.068125 1.749689e-04 9.966077e-10   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000136986 E001 0.3550369 3.240018e-02 2.487120e-01   8 123013170 123013344 175 - 0.194 0.000 -9.732
ENSG00000136986 E002 226.9441373 9.035875e-05 1.170971e-05 3.917812e-04 8 123013345 123014148 804 - 2.310 2.399 0.295
ENSG00000136986 E003 362.9456769 1.725425e-03 2.852213e-02 1.581059e-01 8 123014149 123015164 1016 - 2.532 2.578 0.154
ENSG00000136986 E004 124.4578524 1.462068e-04 6.783710e-01 8.668529e-01 8 123015165 123015441 277 - 2.089 2.085 -0.015
ENSG00000136986 E005 35.6148321 3.830512e-04 3.990133e-01 6.827972e-01 8 123015442 123015445 4 - 1.533 1.582 0.168
ENSG00000136986 E006 96.1767198 5.427658e-04 5.671181e-01 8.049697e-01 8 123015446 123015585 140 - 1.981 1.970 -0.038
ENSG00000136986 E007 17.4100120 7.646784e-03 3.004216e-13 4.176015e-11 8 123015586 123018864 3279 - 0.931 1.516 2.079
ENSG00000136986 E008 2.9778542 5.852859e-03 4.510250e-03 4.610217e-02 8 123018865 123019194 330 - 0.399 0.785 1.757
ENSG00000136986 E009 50.5965428 4.717950e-04 2.680234e-03 3.170082e-02 8 123019195 123019245 51 - 1.747 1.620 -0.428
ENSG00000136986 E010 59.3581090 2.552189e-04 1.584919e-02 1.090737e-01 8 123019246 123019305 60 - 1.803 1.713 -0.305
ENSG00000136986 E011 63.8978961 2.176848e-04 2.635627e-03 3.128988e-02 8 123021447 123021499 53 - 1.841 1.731 -0.372
ENSG00000136986 E012 76.8974612 2.049688e-04 2.646167e-04 5.250775e-03 8 123022684 123022779 96 - 1.924 1.802 -0.413
ENSG00000136986 E013 38.4132908 4.179985e-04 1.035167e-04 2.443356e-03 8 123023713 123023739 27 - 1.650 1.458 -0.658
ENSG00000136986 E014 32.9415366 4.332831e-04 2.449311e-05 7.330806e-04 8 123024986 123025050 65 - 1.596 1.367 -0.786
ENSG00000136986 E015 0.1272623 1.234013e-02 3.153904e-01   8 123025572 123025650 79 - 0.000 0.120 10.573
ENSG00000136986 E016 0.0000000       8 123025723 123025772 50 -      
ENSG00000136986 E017 0.0000000       8 123030605 123030716 112 -      
ENSG00000136986 E018 0.0000000       8 123030717 123030719 3 -      
ENSG00000136986 E019 0.0000000       8 123041970 123042302 333 -      

Help

Please Click HERE to learn more details about the results from DEXseq.