ENSG00000137100

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259632 ENSG00000137100 No_inf pgKDN_inf DCTN3 protein_coding protein_coding 73.66845 76.25983 73.97368 3.379446 2.75506 -0.0439055 62.987295 60.539913 66.4055431 0.8905808 1.8635533 0.133396 0.85746667 0.797225 0.898975 0.10175 0.04550220 0.0455022 FALSE TRUE
ENST00000378911 ENSG00000137100 No_inf pgKDN_inf DCTN3 protein_coding protein_coding 73.66845 76.25983 73.97368 3.379446 2.75506 -0.0439055 3.653498 6.680571 1.9109826 1.8560405 0.8193441 -1.800285 0.04825833 0.084975 0.025725 -0.05925 0.43072757 0.0455022 FALSE FALSE
ENST00000481438 ENSG00000137100 No_inf pgKDN_inf DCTN3 protein_coding protein_coding_CDS_not_defined 73.66845 76.25983 73.97368 3.379446 2.75506 -0.0439055 3.799797 6.793838 0.9982183 0.4529835 0.6400957 -2.754541 0.05090833 0.088850 0.013550 -0.07530 0.04745414 0.0455022   TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137100 E001 0.0000000       9 34613545 34613545 1 -      
ENSG00000137100 E002 0.5000168 0.0358756949 3.666827e-01 0.655374927 9 34613546 34613550 5 - 0.099 0.232 1.468
ENSG00000137100 E003 8.9313748 0.0017925147 6.277871e-01 0.840008694 9 34613551 34613603 53 - 1.018 0.976 -0.156
ENSG00000137100 E004 31.5669792 0.0005203704 4.463142e-01 0.720711538 9 34613604 34613731 128 - 1.489 1.530 0.143
ENSG00000137100 E005 52.8623167 0.0003368465 9.846893e-01 0.998932269 9 34613732 34613871 140 - 1.728 1.732 0.011
ENSG00000137100 E006 1.2597830 0.0101765823 1.063475e-02 0.083611433 9 34613872 34613901 30 - 0.099 0.494 3.053
ENSG00000137100 E007 2.7749410 0.0049963871 9.122474e-05 0.002201997 9 34613902 34614041 140 - 0.179 0.756 3.206
ENSG00000137100 E008 34.9449129 0.0003865154 6.369240e-02 0.254081808 9 34614042 34614101 60 - 1.599 1.512 -0.298
ENSG00000137100 E009 1.8434444 0.0206483441 9.279808e-01 0.978622970 9 34614102 34614132 31 - 0.445 0.460 0.076
ENSG00000137100 E010 0.9966653 0.5576172075 4.996480e-01 0.759890981 9 34614133 34614186 54 - 0.179 0.382 1.465
ENSG00000137100 E011 0.4989145 0.0332717154 3.660801e-01   9 34614187 34614198 12 - 0.099 0.232 1.468
ENSG00000137100 E012 4.3343704 0.0043919750 1.093773e-01 0.347111239 9 34614199 34614709 511 - 0.608 0.807 0.822
ENSG00000137100 E013 42.8493338 0.0003299784 3.396825e-01 0.631367686 9 34614710 34614768 59 - 1.661 1.622 -0.133
ENSG00000137100 E014 7.4549456 0.0043605296 6.000317e-03 0.056478377 9 34614769 34616029 1261 - 0.747 1.036 1.106
ENSG00000137100 E015 54.9657912 0.0004984359 2.673485e-01 0.560621080 9 34616030 34616113 84 - 1.768 1.728 -0.135
ENSG00000137100 E016 7.4486913 0.0278597477 1.567794e-02 0.108323596 9 34616114 34616743 630 - 0.747 1.036 1.107
ENSG00000137100 E017 2.2404364 0.0073610458 8.634068e-02 0.304419049 9 34617671 34617884 214 - 0.357 0.608 1.262
ENSG00000137100 E018 62.9637635 0.0003954430 8.209945e-01 0.935014504 9 34617885 34617971 87 - 1.799 1.809 0.036
ENSG00000137100 E019 54.7832443 0.0002906030 5.355734e-01 0.785276649 9 34618676 34618760 85 - 1.756 1.735 -0.071
ENSG00000137100 E020 38.2803604 0.0004523037 1.886997e-01 0.467192920 9 34620369 34620523 155 - 1.624 1.565 -0.199

Help

Please Click HERE to learn more details about the results from DEXseq.