ENSG00000137145

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361024 ENSG00000137145 No_inf pgKDN_inf DENND4C protein_coding protein_coding 10.30508 14.80867 9.607606 0.1677733 0.7901687 -0.6236664 4.4972348 7.9340135 2.4064524 1.2140510 1.4004013 -1.71697753 0.4212000 0.535850 0.247000 -0.288850 0.47801923 0.01793044 FALSE TRUE
ENST00000380427 ENSG00000137145 No_inf pgKDN_inf DENND4C protein_coding protein_coding 10.30508 14.80867 9.607606 0.1677733 0.7901687 -0.6236664 0.6122280 0.9303479 0.6728197 0.5405137 0.6728197 -0.46169005 0.0624750 0.062050 0.084275 0.022225 0.85767379 0.01793044 FALSE TRUE
ENST00000434457 ENSG00000137145 No_inf pgKDN_inf DENND4C protein_coding protein_coding 10.30508 14.80867 9.607606 0.1677733 0.7901687 -0.6236664 2.5142340 3.3888642 1.8266880 0.5968897 0.3949149 -0.88794614 0.2657167 0.230225 0.201975 -0.028250 0.92013081 0.01793044 FALSE TRUE
ENST00000602925 ENSG00000137145 No_inf pgKDN_inf DENND4C protein_coding protein_coding 10.30508 14.80867 9.607606 0.1677733 0.7901687 -0.6236664 0.8471911 0.3152449 2.0862023 0.1589138 0.5305333 2.68817965 0.0834500 0.020925 0.209275 0.188350 0.01793044 0.01793044 FALSE TRUE
MSTRG.28559.8 ENSG00000137145 No_inf pgKDN_inf DENND4C protein_coding   10.30508 14.80867 9.607606 0.1677733 0.7901687 -0.6236664 1.2715359 1.5594833 1.6081937 1.5594833 1.6081937 0.04409463 0.1156750 0.105850 0.148125 0.042275 0.97626746 0.01793044 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137145 E001 0.7201746 0.1500451092 5.581223e-02 2.353907e-01 9 19230435 19230692 258 + 0.397 0.080 -2.892
ENSG00000137145 E002 1.0797498 0.0218532085 2.602725e-02 1.491768e-01 9 19230693 19230796 104 + 0.489 0.147 -2.376
ENSG00000137145 E003 0.8524759 0.0136959279 3.820127e-01 6.683119e-01 9 19230797 19230833 37 + 0.341 0.205 -0.984
ENSG00000137145 E004 6.1397350 0.0025551107 4.370295e-01 7.134436e-01 9 19276158 19276479 322 + 0.895 0.808 -0.337
ENSG00000137145 E005 0.2373413 0.0157987212 1.361816e-01   9 19276480 19276671 192 + 0.203 0.000 -12.471
ENSG00000137145 E006 3.3033081 0.0673339405 5.217978e-01 7.755357e-01 9 19286769 19287021 253 + 0.688 0.581 -0.461
ENSG00000137145 E007 1.2225824 0.0108773372 5.505343e-01 7.948458e-01 9 19288596 19288665 70 + 0.396 0.302 -0.569
ENSG00000137145 E008 1.0763140 0.0357162279 2.897237e-02 1.595788e-01 9 19290704 19290757 54 + 0.489 0.147 -2.376
ENSG00000137145 E009 3.5177749 0.0041505981 2.087493e-02 1.302034e-01 9 19290758 19290876 119 + 0.804 0.507 -1.279
ENSG00000137145 E010 6.6107998 0.0035692748 9.811170e-02 3.266924e-01 9 19296008 19296246 239 + 0.971 0.794 -0.676
ENSG00000137145 E011 3.2834432 0.0044502038 5.265128e-02 2.280317e-01 9 19298056 19298122 67 + 0.761 0.507 -1.109
ENSG00000137145 E012 2.9180258 0.0047929747 8.239846e-02 2.956175e-01 9 19299229 19299287 59 + 0.714 0.479 -1.054
ENSG00000137145 E013 4.8913458 0.0029234304 1.300928e-01 3.826375e-01 9 19300187 19300331 145 + 0.861 0.683 -0.713
ENSG00000137145 E014 5.8566317 0.0025476385 2.941322e-02 1.611472e-01 9 19305352 19305527 176 + 0.957 0.718 -0.931
ENSG00000137145 E015 3.4270112 0.0040831898 3.161092e-01 6.090212e-01 9 19316417 19316517 101 + 0.714 0.581 -0.569
ENSG00000137145 E016 4.7735940 0.0177816881 3.530727e-01 6.428758e-01 9 19316621 19316839 219 + 0.824 0.701 -0.495
ENSG00000137145 E017 4.3338127 0.0037083287 4.497300e-01 7.233211e-01 9 19324362 19324507 146 + 0.661 0.750 0.370
ENSG00000137145 E018 2.3393380 0.0337378415 8.921211e-01 9.641748e-01 9 19325939 19325974 36 + 0.530 0.507 -0.109
ENSG00000137145 E019 5.3074632 0.0098778221 9.027414e-01 9.688647e-01 9 19326064 19326194 131 + 0.783 0.794 0.044
ENSG00000137145 E020 6.3155878 0.0022959547 4.469512e-01 7.211496e-01 9 19328030 19328162 133 + 0.804 0.883 0.306
ENSG00000137145 E021 5.9506280 0.0024371070 3.764655e-03 4.073078e-02 9 19331978 19332184 207 + 0.998 0.683 -1.228
ENSG00000137145 E022 0.0000000       9 19332185 19332188 4 +      
ENSG00000137145 E023 5.8447611 0.0911603899 1.279881e-01 3.791403e-01 9 19334977 19335105 129 + 0.956 0.718 -0.931
ENSG00000137145 E024 7.6959178 0.0022210361 5.943939e-02 2.445872e-01 9 19336270 19336403 134 + 1.035 0.847 -0.706
ENSG00000137145 E025 2.5660701 0.0131867203 2.872183e-01 5.806094e-01 9 19336404 19336414 11 + 0.631 0.479 -0.706
ENSG00000137145 E026 0.3622142 0.0165534420 3.728446e-01   9 19336415 19336685 271 + 0.203 0.080 -1.569
ENSG00000137145 E027 3.3467348 0.0044700248 4.473374e-01 7.215080e-01 9 19336686 19336832 147 + 0.566 0.664 0.431
ENSG00000137145 E028 0.2542726 0.2326121794 4.621949e-01   9 19337601 19337672 72 + 0.000 0.147 10.331
ENSG00000137145 E029 4.4989534 0.0031570214 2.159973e-02 1.331535e-01 9 19340992 19341070 79 + 0.878 0.604 -1.121
ENSG00000137145 E030 3.6517064 0.0556554264 6.478045e-02 2.565620e-01 9 19341071 19341114 44 + 0.804 0.533 -1.154
ENSG00000137145 E031 2.6727872 0.0868337635 6.916710e-02 2.657211e-01 9 19342633 19342668 36 + 0.714 0.416 -1.376
ENSG00000137145 E032 5.1936466 0.0048619265 7.527274e-01 9.026303e-01 9 19342669 19342779 111 + 0.761 0.794 0.132
ENSG00000137145 E033 14.0072966 0.0215493075 3.616906e-01 6.511052e-01 9 19345921 19346279 359 + 1.218 1.129 -0.315
ENSG00000137145 E034 10.4789318 0.0015490338 9.222759e-01 9.759845e-01 9 19346280 19346555 276 + 1.047 1.051 0.016
ENSG00000137145 E035 8.8847110 0.0017638062 7.782487e-01 9.148664e-01 9 19346556 19346727 172 + 0.971 0.993 0.083
ENSG00000137145 E036 14.7678805 0.0009387432 5.288221e-01 7.803204e-01 9 19346728 19347086 359 + 1.218 1.166 -0.182
ENSG00000137145 E037 9.4263788 0.0016101356 1.721219e-01 4.448089e-01 9 19350702 19350879 178 + 0.927 1.051 0.460
ENSG00000137145 E038 5.8001114 0.0276099294 9.895913e-01 1.000000e+00 9 19352073 19352182 110 + 0.824 0.821 -0.010
ENSG00000137145 E039 9.5387492 0.0052767867 3.434635e-01 6.346567e-01 9 19352490 19352665 176 + 0.957 1.043 0.320
ENSG00000137145 E040 10.8432181 0.0013545649 9.428358e-01 9.841203e-01 9 19356972 19357154 183 + 1.069 1.059 -0.038
ENSG00000137145 E041 1.0995347 0.1072984053 4.001030e-01 6.836253e-01 9 19357155 19357695 541 + 0.396 0.256 -0.891
ENSG00000137145 E042 12.2634044 0.0012803753 1.908722e-01 4.701974e-01 9 19357965 19358160 196 + 1.176 1.066 -0.395
ENSG00000137145 E043 14.1290998 0.0076940462 3.415798e-01 6.330998e-01 9 19360244 19360489 246 + 1.217 1.135 -0.292
ENSG00000137145 E044 9.3872504 0.0015145392 6.747670e-01 8.652809e-01 9 19361846 19361963 118 + 0.984 1.019 0.128
ENSG00000137145 E045 7.8683264 0.0020114897 6.038304e-01 8.272031e-01 9 19369837 19369987 151 + 0.971 0.916 -0.206
ENSG00000137145 E046 0.0000000       9 19371756 19371820 65 +      
ENSG00000137145 E047 185.4097335 0.0001566171 1.869996e-13 2.675235e-11 9 19372037 19374397 2361 + 2.176 2.304 0.425

Help

Please Click HERE to learn more details about the results from DEXseq.