ENSG00000137409

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373616 ENSG00000137409 No_inf pgKDN_inf MTCH1 protein_coding protein_coding 117.0761 97.78586 123.9856 1.256636 0.288419 0.3424435 56.020875 44.623696 64.1760416 5.296901 4.5081826 0.5241263 0.47728333 0.456325 0.517750 0.061425 8.190114e-01 2.879664e-05 FALSE  
ENST00000373627 ENSG00000137409 No_inf pgKDN_inf MTCH1 protein_coding protein_coding 117.0761 97.78586 123.9856 1.256636 0.288419 0.3424435 34.765433 20.971495 41.7407789 5.575053 4.4081819 0.9926856 0.29079167 0.214750 0.336425 0.121675 4.471938e-01 2.879664e-05 FALSE  
ENST00000695056 ENSG00000137409 No_inf pgKDN_inf MTCH1 protein_coding retained_intron 117.0761 97.78586 123.9856 1.256636 0.288419 0.3424435 2.685245 5.562328 0.1458024 1.094638 0.1458024 -5.1604903 0.02531667 0.056650 0.001175 -0.055475 2.879664e-05 2.879664e-05 FALSE  
ENST00000695063 ENSG00000137409 No_inf pgKDN_inf MTCH1 protein_coding nonsense_mediated_decay 117.0761 97.78586 123.9856 1.256636 0.288419 0.3424435 8.061534 5.078990 6.7368565 3.144060 2.3786325 0.4068362 0.06687500 0.050850 0.054400 0.003550 8.375587e-01 2.879664e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137409 E001 0.6269010 0.1414678062 1.859808e-01 4.639015e-01 6 36965807 36968140 2334 - 0.091 0.307 2.138
ENSG00000137409 E002 6.0741325 0.0280522394 3.032854e-02 1.638676e-01 6 36968141 36968149 9 - 0.696 0.965 1.050
ENSG00000137409 E003 7.2795079 0.0277405229 1.242598e-01 3.734858e-01 6 36968150 36968156 7 - 0.820 0.999 0.682
ENSG00000137409 E004 7.6607606 0.0203471082 5.825473e-02 2.416786e-01 6 36968157 36968157 1 - 0.820 1.032 0.801
ENSG00000137409 E005 172.4180679 0.0029000253 6.397017e-02 2.547419e-01 6 36968158 36968447 290 - 2.209 2.268 0.198
ENSG00000137409 E006 65.6303086 0.0055899930 9.614026e-01 9.915533e-01 6 36968448 36968478 31 - 1.822 1.826 0.015
ENSG00000137409 E007 220.6024113 0.0000876461 6.813912e-01 8.682781e-01 6 36968479 36968759 281 - 2.349 2.342 -0.020
ENSG00000137409 E008 153.1886202 0.0006812447 6.930070e-02 2.660448e-01 6 36968760 36968872 113 - 2.209 2.165 -0.150
ENSG00000137409 E009 73.7652147 0.0002811517 3.192246e-01 6.119662e-01 6 36968873 36968874 2 - 1.889 1.857 -0.111
ENSG00000137409 E010 92.1459570 0.0023885104 5.918535e-01 8.197069e-01 6 36968875 36968911 37 - 1.978 1.960 -0.061
ENSG00000137409 E011 99.8983018 0.0011683369 9.389074e-01 9.824047e-01 6 36968912 36968974 63 - 2.002 2.006 0.015
ENSG00000137409 E012 39.3217096 0.0091661993 4.263245e-08 2.690625e-06 6 36968975 36969294 320 - 1.398 1.748 1.193
ENSG00000137409 E013 10.5194336 0.0027913973 2.154396e-03 2.700330e-02 6 36969295 36969300 6 - 0.903 1.180 1.013
ENSG00000137409 E014 27.4029888 0.0095535661 6.083462e-04 1.017125e-02 6 36969301 36969465 165 - 1.319 1.558 0.827
ENSG00000137409 E015 13.2148429 0.0161889897 9.330381e-03 7.689865e-02 6 36969466 36969515 50 - 1.014 1.260 0.883
ENSG00000137409 E016 59.5330165 0.0002492596 2.501286e-18 5.865407e-16 6 36969516 36970038 523 - 1.573 1.925 1.193
ENSG00000137409 E017 53.6192723 0.0034538786 7.123829e-01 8.838273e-01 6 36970039 36970055 17 - 1.745 1.729 -0.052
ENSG00000137409 E018 61.0405744 0.0023823562 4.884322e-01 7.517386e-01 6 36970056 36970082 27 - 1.806 1.779 -0.093
ENSG00000137409 E019 59.1123882 0.0002532505 7.666418e-02 2.830736e-01 6 36970083 36970114 32 - 1.811 1.744 -0.227
ENSG00000137409 E020 2.2221792 0.0085196471 2.633586e-01 5.562991e-01 6 36970115 36970405 291 - 0.420 0.583 0.790
ENSG00000137409 E021 81.6500015 0.0001817244 1.665772e-02 1.125273e-01 6 36970406 36970473 68 - 1.954 1.876 -0.260
ENSG00000137409 E022 1.2250369 0.0107402951 8.873050e-01 9.622979e-01 6 36970474 36970490 17 - 0.336 0.359 0.138
ENSG00000137409 E023 2.1947377 0.0077032204 7.832316e-01 9.165837e-01 6 36970491 36970646 156 - 0.523 0.485 -0.184
ENSG00000137409 E024 72.4301486 0.0006055658 4.928853e-02 2.188464e-01 6 36970647 36970689 43 - 1.899 1.829 -0.233
ENSG00000137409 E025 46.7374591 0.0003505617 2.300341e-01 5.185646e-01 6 36970690 36970694 5 - 1.703 1.652 -0.172
ENSG00000137409 E026 24.1211546 0.0006311776 1.588568e-10 1.557779e-08 6 36970695 36972651 1957 - 1.155 1.558 1.403
ENSG00000137409 E027 35.7583199 0.0004180537 3.621246e-01 6.513598e-01 6 36972652 36972702 51 - 1.586 1.543 -0.148
ENSG00000137409 E028 108.1296718 0.0043984542 2.507206e-01 5.418048e-01 6 36972703 36972796 94 - 2.058 2.016 -0.143
ENSG00000137409 E029 5.6382522 0.0024581202 2.128732e-06 8.969614e-05 6 36972797 36973316 520 - 0.457 1.021 2.348
ENSG00000137409 E030 0.4907934 0.0896627123 9.354396e-01   6 36975654 36975657 4 - 0.166 0.180 0.138
ENSG00000137409 E031 77.5668414 0.0061812311 6.603791e-01 8.583018e-01 6 36975658 36975717 60 - 1.904 1.887 -0.057
ENSG00000137409 E032 0.8348194 0.0125693929 6.454441e-02 2.560356e-01 6 36975718 36976277 560 - 0.380 0.099 -2.447
ENSG00000137409 E033 0.7431845 0.0140911743 3.545215e-01 6.442740e-01 6 36976278 36976497 220 - 0.166 0.307 1.138
ENSG00000137409 E034 0.7328615 0.0497215591 9.151278e-01 9.733859e-01 6 36976498 36976598 101 - 0.230 0.248 0.138
ENSG00000137409 E035 1.7298416 0.0505068986 2.499676e-01 5.409338e-01 6 36976599 36977198 600 - 0.336 0.520 0.986
ENSG00000137409 E036 57.8935653 0.0077844102 6.409801e-01 8.476017e-01 6 36977199 36977224 26 - 1.780 1.760 -0.069
ENSG00000137409 E037 52.3149864 0.0033317294 1.790705e-01 4.541388e-01 6 36977225 36977250 26 - 1.756 1.695 -0.206
ENSG00000137409 E038 1.3793676 0.0091916138 2.065129e-02 1.294620e-01 6 36977251 36977633 383 - 0.166 0.520 2.308
ENSG00000137409 E039 55.2477404 0.0011799582 1.453587e-01 4.057435e-01 6 36977634 36977668 35 - 1.778 1.719 -0.201
ENSG00000137409 E040 48.4350699 0.0054297509 3.221621e-02 1.697986e-01 6 36977669 36977691 23 - 1.745 1.635 -0.374
ENSG00000137409 E041 4.2172173 0.1035588592 1.228810e-01 3.710163e-01 6 36977692 36977796 105 - 0.552 0.839 1.202
ENSG00000137409 E042 5.0914328 0.0644005232 2.330173e-02 1.394226e-01 6 36977797 36978077 281 - 0.580 0.927 1.411
ENSG00000137409 E043 79.5053621 0.0019937448 1.225729e-01 3.705216e-01 6 36978078 36978155 78 - 1.933 1.876 -0.191
ENSG00000137409 E044 75.7239883 0.0014030901 1.126356e-01 3.530887e-01 6 36978505 36978611 107 - 1.912 1.855 -0.193
ENSG00000137409 E045 0.8416767 0.0132604245 3.065079e-01 5.996952e-01 6 36978612 36978837 226 - 0.336 0.180 -1.184
ENSG00000137409 E046 6.6016266 0.0023710323 1.579585e-04 3.439376e-03 6 36978970 36981587 2618 - 0.630 1.042 1.616
ENSG00000137409 E047 59.8348758 0.0002852838 2.263782e-03 2.804843e-02 6 36981588 36981672 85 - 1.838 1.721 -0.396
ENSG00000137409 E048 0.4797798 0.0157093797 3.652160e-01   6 36981673 36981813 141 - 0.230 0.099 -1.447
ENSG00000137409 E049 0.0000000       6 36984680 36984805 126 -      
ENSG00000137409 E050 0.0000000       6 36985116 36985434 319 -      
ENSG00000137409 E051 0.4998298 0.0168318725 2.780945e-01   6 36985807 36985852 46 - 0.091 0.248 1.723
ENSG00000137409 E052 76.5834042 0.0022638862 9.968607e-04 1.497624e-02 6 36985853 36986298 446 - 1.948 1.821 -0.428

Help

Please Click HERE to learn more details about the results from DEXseq.