ENSG00000137449

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000345451 ENSG00000137449 No_inf pgKDN_inf CPEB2 protein_coding protein_coding 33.36402 23.78743 39.23437 0.6690973 0.6933307 0.72168 21.1057587 15.889527 24.809377 2.3667762 0.8058773 0.6424830 0.63609167 0.662175 0.632225 -0.029950 0.88357886 0.03742179 FALSE  
ENST00000382395 ENSG00000137449 No_inf pgKDN_inf CPEB2 protein_coding protein_coding 33.36402 23.78743 39.23437 0.6690973 0.6933307 0.72168 2.1701697 2.309786 2.986611 1.3943267 1.3771644 0.3693406 0.06976667 0.097050 0.077875 -0.019175 0.93769173 0.03742179 FALSE  
ENST00000382401 ENSG00000137449 No_inf pgKDN_inf CPEB2 protein_coding protein_coding 33.36402 23.78743 39.23437 0.6690973 0.6933307 0.72168 2.6212620 2.041220 3.191663 2.0412201 1.6942126 0.6423391 0.08040833 0.091400 0.080575 -0.010825 0.57855064 0.03742179 FALSE  
ENST00000507071 ENSG00000137449 No_inf pgKDN_inf CPEB2 protein_coding protein_coding 33.36402 23.78743 39.23437 0.6690973 0.6933307 0.72168 5.4875002 1.354619 6.556704 0.8170527 0.8871313 2.2666706 0.15146667 0.058800 0.166525 0.107725 0.37388153 0.03742179 FALSE  
ENST00000538197 ENSG00000137449 No_inf pgKDN_inf CPEB2 protein_coding protein_coding 33.36402 23.78743 39.23437 0.6690973 0.6933307 0.72168 0.7831928 1.274922 0.000000 0.5185745 0.0000000 -7.0055370 0.02706667 0.053075 0.000000 -0.053075 0.03742179 0.03742179 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137449 E001 0.3804973 0.0158517036 0.049426189   4 15002481 15002673 193 + 0.000 0.279 11.791
ENSG00000137449 E002 40.1508762 0.0041556490 0.009769818 0.07909742 4 15002674 15004335 1662 + 1.655 1.533 -0.418
ENSG00000137449 E003 7.2536591 0.0425396823 0.245297983 0.53573199 4 15007305 15007366 62 + 0.962 0.827 -0.515
ENSG00000137449 E004 27.6289121 0.0183765660 0.147707313 0.40911305 4 15007367 15007586 220 + 1.490 1.389 -0.350
ENSG00000137449 E005 1.0992243 0.2628140347 0.955033787 0.98905929 4 15007587 15007595 9 + 0.300 0.343 0.273
ENSG00000137449 E006 3.6292319 0.0040742316 0.402697766 0.68579312 4 15008338 15008427 90 + 0.698 0.603 -0.405
ENSG00000137449 E007 16.9584297 0.0053936918 0.137857997 0.39507084 4 15017188 15017278 91 + 1.286 1.189 -0.344
ENSG00000137449 E008 0.1272623 0.0123620279 0.367790395   4 15017279 15017434 156 + 0.000 0.114 11.974
ENSG00000137449 E009 12.5990589 0.0010817226 0.194357449 0.47421283 4 15033161 15033211 51 + 1.163 1.073 -0.323
ENSG00000137449 E010 1.8504267 0.0218464615 0.151605188 0.41495428 4 15040464 15040487 24 + 0.341 0.569 1.180
ENSG00000137449 E011 28.5523762 0.0004635067 0.592979509 0.82056352 4 15052414 15052584 171 + 1.470 1.457 -0.042
ENSG00000137449 E012 6.8214722 0.0129361935 0.968506512 0.99364123 4 15054128 15054132 5 + 0.879 0.899 0.073
ENSG00000137449 E013 16.1661115 0.0426029029 0.743493886 0.89860560 4 15054133 15054217 85 + 1.244 1.205 -0.138
ENSG00000137449 E014 20.2309838 0.0094321238 0.743795359 0.89867543 4 15058421 15058539 119 + 1.304 1.344 0.139
ENSG00000137449 E015 21.8029528 0.0007721042 0.665445690 0.86082188 4 15059187 15059301 115 + 1.333 1.378 0.156
ENSG00000137449 E016 39.0874740 0.0032915318 0.325843532 0.61834146 4 15062079 15062260 182 + 1.611 1.576 -0.119
ENSG00000137449 E017 1.7033435 0.0088839239 0.881678065 0.96026870 4 15063738 15063871 134 + 0.414 0.448 0.180
ENSG00000137449 E018 824.9791352 0.0027978258 0.011075950 0.08594019 4 15066153 15070153 4001 + 2.895 2.932 0.123

Help

Please Click HERE to learn more details about the results from DEXseq.