ENSG00000137500

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000455220 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding protein_coding 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 7.4117942 7.6798781 9.874576 0.6043095 0.9865705 0.3622183 0.28672500 0.292725 0.370950 0.078225 0.79274530 0.02191576 FALSE TRUE
ENST00000525503 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding nonsense_mediated_decay 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 3.0957599 2.4702951 3.614655 0.3692913 1.4203576 0.5473318 0.12633333 0.095575 0.146000 0.050425 0.97267089 0.02191576 FALSE TRUE
ENST00000525504 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding protein_coding_CDS_not_defined 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 2.8725734 3.8485824 1.516066 0.6291667 0.6637934 -1.3382533 0.11160833 0.140475 0.058850 -0.081625 0.38004246 0.02191576   FALSE
ENST00000527025 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding nonsense_mediated_decay 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 0.3888353 1.1665060 0.000000 1.1665060 0.0000000 -6.8783649 0.01748333 0.052450 0.000000 -0.052450 0.86175447 0.02191576 FALSE FALSE
ENST00000527495 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding protein_coding 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 3.4035073 4.6377343 0.000000 2.1776051 0.0000000 -8.8603838 0.12150000 0.158325 0.000000 -0.158325 0.02191576 0.02191576 FALSE TRUE
ENST00000529312 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding nonsense_mediated_decay 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 1.4735292 0.5769916 2.372731 0.5769916 0.9581969 2.0212046 0.05765000 0.022625 0.084750 0.062125 0.42443825 0.02191576 FALSE TRUE
ENST00000529745 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding nonsense_mediated_decay 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 2.0021577 0.7659277 4.279075 0.7659277 1.5312508 2.4666725 0.07853333 0.024975 0.173200 0.148225 0.28848543 0.02191576 FALSE TRUE
ENST00000534753 ENSG00000137500 No_inf pgKDN_inf CCDC90B protein_coding nonsense_mediated_decay 25.96778 26.97326 26.57246 1.925294 1.738243 -0.0215901 0.5661678 0.0000000 1.698503 0.0000000 1.6985033 7.4165892 0.01787500 0.000000 0.053625 0.053625 0.83784639 0.02191576 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137500 E001 6.3810654 0.0022872565 0.65207588 0.85344232 11 83259081 83261316 2236 - 0.843 0.891 0.183
ENSG00000137500 E002 2.3124027 0.0257182168 0.57243772 0.80844071 11 83261317 83261455 139 - 0.559 0.478 -0.388
ENSG00000137500 E003 0.2442663 0.0164456157 0.97043729   11 83261456 83261461 6 - 0.093 0.097 0.072
ENSG00000137500 E004 21.0234359 0.0007497620 0.10016372 0.33071503 11 83261462 83261729 268 - 1.287 1.391 0.359
ENSG00000137500 E005 8.1227188 0.0018538740 0.23864683 0.52769068 11 83261730 83261756 27 - 0.899 1.012 0.423
ENSG00000137500 E006 9.8413210 0.0039887806 0.27795880 0.57121423 11 83261757 83261794 38 - 0.982 1.081 0.361
ENSG00000137500 E007 5.9050752 0.0895371774 0.63537162 0.84437544 11 83261795 83261795 1 - 0.796 0.876 0.311
ENSG00000137500 E008 19.1928290 0.0138569060 0.70659569 0.88098229 11 83261796 83261890 95 - 1.318 1.292 -0.094
ENSG00000137500 E009 15.6348924 0.0009136776 0.66073836 0.85841554 11 83261891 83261928 38 - 1.236 1.206 -0.109
ENSG00000137500 E010 15.0860980 0.0011148221 0.12296168 0.37111446 11 83261929 83261966 38 - 1.260 1.148 -0.398
ENSG00000137500 E011 13.0707701 0.0011321034 0.66819157 0.86191759 11 83265865 83265889 25 - 1.165 1.132 -0.117
ENSG00000137500 E012 13.6665480 0.0062949885 0.51885874 0.77366198 11 83265890 83265899 10 - 1.192 1.140 -0.187
ENSG00000137500 E013 16.3862515 0.0036176022 0.95105756 0.98758810 11 83265900 83265915 16 - 1.242 1.238 -0.014
ENSG00000137500 E014 24.0281273 0.0085854774 0.37739481 0.66437353 11 83265916 83265979 64 - 1.428 1.368 -0.207
ENSG00000137500 E015 0.0000000       11 83266867 83267038 172 -      
ENSG00000137500 E016 0.4895339 0.4290493920 0.96834756   11 83267039 83267472 434 - 0.169 0.177 0.073
ENSG00000137500 E017 0.4988833 0.0152681965 0.29657343   11 83273246 83273646 401 - 0.093 0.244 1.657
ENSG00000137500 E018 17.1689636 0.0009013537 0.13337867 0.38796490 11 83273647 83273676 30 - 1.308 1.206 -0.361
ENSG00000137500 E019 15.2468516 0.0009483462 0.27951836 0.57280076 11 83273677 83273700 24 - 1.248 1.170 -0.276
ENSG00000137500 E020 0.0000000       11 83273701 83273738 38 -      
ENSG00000137500 E021 25.2218495 0.0065708336 0.93447758 0.98106717 11 83273793 83273864 72 - 1.416 1.421 0.015
ENSG00000137500 E022 0.4901668 0.0734661564 0.96854445   11 83273865 83273950 86 - 0.170 0.177 0.072
ENSG00000137500 E023 15.4447162 0.0009210397 0.64961225 0.85237711 11 83273951 83273992 42 - 1.199 1.232 0.117
ENSG00000137500 E024 0.6266187 0.0365336774 0.16282307 0.43138004 11 83273993 83274176 184 - 0.093 0.302 2.072
ENSG00000137500 E025 0.6249819 0.0151018931 0.15690136 0.42326404 11 83274177 83274442 266 - 0.093 0.302 2.072
ENSG00000137500 E026 0.7530610 0.0267126168 0.08556553 0.30277464 11 83274443 83274638 196 - 0.093 0.353 2.394
ENSG00000137500 E027 21.8630499 0.0006658006 0.21199596 0.49709969 11 83274639 83274740 102 - 1.318 1.395 0.266
ENSG00000137500 E028 0.0000000       11 83274741 83274763 23 -      
ENSG00000137500 E029 17.7057304 0.0198150822 0.20446286 0.48733868 11 83278726 83278829 104 - 1.212 1.324 0.393
ENSG00000137500 E030 0.2373413 0.0157581382 0.25936094   11 83278830 83278830 1 - 0.170 0.000 -11.452
ENSG00000137500 E031 22.2747556 0.0020335078 0.97535133 0.99562038 11 83280141 83280260 120 - 1.366 1.368 0.008
ENSG00000137500 E032 1.5062544 0.0092102370 0.01368913 0.09857268 11 83285127 83285211 85 - 0.170 0.545 2.394
ENSG00000137500 E033 2.4764775 0.0062241145 0.14870871 0.41073189 11 83285212 83285552 341 - 0.427 0.630 0.965
ENSG00000137500 E034 8.5163810 0.0017862950 0.14033802 0.39866821 11 83285553 83285872 320 - 1.043 0.904 -0.513
ENSG00000137500 E035 11.3005701 0.0013737166 0.08028619 0.29086822 11 83285873 83286099 227 - 1.157 1.012 -0.526
ENSG00000137500 E036 0.2374063 0.3092884953 0.32972930   11 83286100 83286390 291 - 0.170 0.000 -11.453

Help

Please Click HERE to learn more details about the results from DEXseq.