ENSG00000137776

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000380516 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding protein_coding 64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 1.148695 3.446084 0.0000000 3.446084 0.0000000 -8.4329947 0.01794167 0.053825 0.000000 -0.053825 8.539400e-01 5.660626e-10 FALSE TRUE
ENST00000432750 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding protein_coding 64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 6.715097 8.635921 4.5022980 1.376309 2.7589145 -0.9381573 0.10284167 0.133600 0.069025 -0.064575 5.162252e-01 5.660626e-10 FALSE TRUE
MSTRG.9681.2 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding   64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 3.525432 8.139495 0.0000000 1.573533 0.0000000 -9.6705668 0.05732500 0.129625 0.000000 -0.129625 5.660626e-10 5.660626e-10 TRUE TRUE
MSTRG.9681.4 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding   64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 4.655246 1.746514 8.7186758 1.746514 3.8673185 2.3130481 0.07505833 0.025025 0.142700 0.117675 2.504822e-01 5.660626e-10 FALSE TRUE
MSTRG.9681.5 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding   64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 2.677958 4.584920 0.8339412 1.828755 0.4814882 -2.4448252 0.04227500 0.074375 0.013175 -0.061200 5.634493e-01 5.660626e-10 TRUE TRUE
MSTRG.9681.9 ENSG00000137776 No_inf pgKDN_inf SLTM protein_coding   64.17431 63.9073 64.0743 2.157619 3.308712 0.003764678 23.032712 14.457537 29.0285151 2.656958 1.9613704 1.0051484 0.36290000 0.226525 0.458150 0.231625 5.737823e-02 5.660626e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137776 E001 0.0000000       15 58879050 58879050 1 -      
ENSG00000137776 E002 0.1170040 0.0117540823 5.501584e-01   15 58879051 58879055 5 - 0.094 0.000 -10.762
ENSG00000137776 E003 0.2346346 0.0156879116 2.499573e-01   15 58879056 58879057 2 - 0.171 0.000 -11.763
ENSG00000137776 E004 0.6066337 0.0143829788 6.740363e-01 0.8649498787 15 58879058 58879060 3 - 0.237 0.175 -0.545
ENSG00000137776 E005 0.8521909 0.0125060406 7.292141e-01 0.8920109380 15 58879061 58879062 2 - 0.293 0.242 -0.375
ENSG00000137776 E006 28.7892389 0.0136793996 4.218833e-03 0.0440818590 15 58879063 58879418 356 - 1.352 1.565 0.734
ENSG00000137776 E007 10.2641479 0.0028104592 1.816445e-02 0.1190378611 15 58879419 58879424 6 - 0.929 1.143 0.786
ENSG00000137776 E008 9.8916754 0.0027300562 2.169165e-02 0.1335951794 15 58879425 58879428 4 - 0.916 1.127 0.777
ENSG00000137776 E009 10.3992440 0.0035959742 7.970639e-03 0.0690029620 15 58879429 58879431 3 - 0.916 1.158 0.888
ENSG00000137776 E010 37.4654631 0.0050942707 1.039896e-02 0.0823944176 15 58879432 58879559 128 - 1.504 1.650 0.499
ENSG00000137776 E011 79.9653304 0.0040652840 3.654681e-01 0.6540516867 15 58879560 58879776 217 - 1.887 1.928 0.138
ENSG00000137776 E012 72.1304116 0.0004169912 9.464414e-01 0.9856943807 15 58879777 58879979 203 - 1.861 1.866 0.016
ENSG00000137776 E013 57.9075643 0.0029876521 8.037875e-01 0.9270951707 15 58879980 58880107 128 - 1.763 1.777 0.046
ENSG00000137776 E014 1.3978096 0.0110066939 2.135491e-04 0.0044094775 15 58883479 58883625 147 - 0.000 0.572 14.198
ENSG00000137776 E015 60.6300340 0.0094481615 6.148257e-01 0.8326849259 15 58883626 58883786 161 - 1.803 1.777 -0.088
ENSG00000137776 E016 54.2583668 0.0013413438 7.199104e-01 0.8871018505 15 58886975 58887119 145 - 1.733 1.751 0.060
ENSG00000137776 E017 0.1265070 0.0123101306 5.264527e-01   15 58887120 58887124 5 - 0.000 0.096 10.738
ENSG00000137776 E018 37.4714995 0.0003890865 6.375718e-02 0.2542037953 15 58887226 58887291 66 - 1.535 1.628 0.315
ENSG00000137776 E019 68.9589441 0.0002534627 8.209195e-01 0.9350145039 15 58887292 58887456 165 - 1.839 1.850 0.035
ENSG00000137776 E020 47.4115159 0.0006807307 1.044271e-01 0.3377412602 15 58887457 58887540 84 - 1.645 1.719 0.250
ENSG00000137776 E021 1.1167182 0.0136081933 3.033786e-01 0.5967113680 15 58887541 58887620 80 - 0.237 0.396 1.040
ENSG00000137776 E022 63.0122479 0.0038259793 4.681061e-01 0.7364242847 15 58888385 58888555 171 - 1.788 1.823 0.119
ENSG00000137776 E023 0.2543986 0.0160482358 2.347859e-01   15 58888556 58888573 18 - 0.000 0.175 11.738
ENSG00000137776 E024 0.3709943 0.0166194818 5.700328e-01   15 58888574 58888729 156 - 0.094 0.175 1.040
ENSG00000137776 E025 0.1265070 0.0123101306 5.264527e-01   15 58889144 58889429 286 - 0.000 0.096 10.738
ENSG00000137776 E026 45.8798361 0.0035422630 8.229622e-01 0.9356232070 15 58889430 58889554 125 - 1.675 1.667 -0.029
ENSG00000137776 E027 65.4288684 0.0002343718 5.142916e-01 0.7710020706 15 58890281 58890461 181 - 1.833 1.811 -0.073
ENSG00000137776 E028 1.2308321 0.1351341797 5.541366e-01 0.7970157798 15 58890462 58890480 19 - 0.293 0.396 0.626
ENSG00000137776 E029 73.0702938 0.0018427555 3.107630e-01 0.6039018976 15 58892897 58893060 164 - 1.888 1.851 -0.124
ENSG00000137776 E030 61.5230864 0.0003396184 4.847256e-01 0.7487881846 15 58893279 58893364 86 - 1.781 1.810 0.098
ENSG00000137776 E031 48.6284235 0.0039752419 8.153691e-01 0.9324876171 15 58893821 58893901 81 - 1.688 1.702 0.047
ENSG00000137776 E032 18.7376236 0.0336921566 9.651955e-01 0.9927275169 15 58893902 58893925 24 - 1.292 1.298 0.021
ENSG00000137776 E033 11.6525887 0.0242746193 7.621983e-01 0.9072585480 15 58893926 58893987 62 - 1.083 1.119 0.131
ENSG00000137776 E034 10.3546685 0.0014126341 2.802255e-01 0.5735307179 15 58894090 58894157 68 - 1.100 1.008 -0.335
ENSG00000137776 E035 16.3607910 0.0008251046 4.660317e-01 0.7348757063 15 58894158 58894188 31 - 1.264 1.215 -0.175
ENSG00000137776 E036 12.3366785 0.0010752563 5.626249e-01 0.8023771938 15 58894189 58894193 5 - 1.147 1.103 -0.160
ENSG00000137776 E037 14.8506481 0.0010695858 9.437907e-02 0.3197387441 15 58894433 58894458 26 - 1.259 1.135 -0.437
ENSG00000137776 E038 29.5948782 0.0166014020 7.589847e-01 0.9053787101 15 58894459 58894582 124 - 1.494 1.478 -0.055
ENSG00000137776 E039 33.2748723 0.0004323314 7.647274e-01 0.9085085754 15 58897115 58897233 119 - 1.541 1.528 -0.045
ENSG00000137776 E040 0.8770870 0.1595890385 8.371688e-02 0.2984260561 15 58897234 58897597 364 - 0.094 0.396 2.625
ENSG00000137776 E041 1.1349773 0.0793739658 2.069305e-02 0.1295701716 15 58897982 58898802 821 - 0.094 0.475 3.040
ENSG00000137776 E042 15.9911849 0.0009140965 3.185070e-01 0.6112617322 15 58898803 58898815 13 - 1.264 1.194 -0.247
ENSG00000137776 E043 21.9773319 0.0067368346 3.626248e-01 0.6519051101 15 58898816 58898852 37 - 1.392 1.329 -0.217
ENSG00000137776 E044 4.5834251 0.0031627057 6.182194e-02 0.2498116758 15 58898853 58899468 616 - 0.617 0.842 0.925
ENSG00000137776 E045 42.0235312 0.0044023647 2.212286e-02 0.1351426350 15 58899469 58899610 142 - 1.691 1.571 -0.407
ENSG00000137776 E046 31.1819555 0.0004794150 2.843514e-02 0.1578611444 15 58899611 58899704 94 - 1.562 1.448 -0.391
ENSG00000137776 E047 11.3077447 0.0012155870 6.425088e-02 0.2552522919 15 58899705 58899709 5 - 1.162 1.008 -0.558
ENSG00000137776 E048 22.9530203 0.0019581826 2.648145e-01 0.5578449857 15 58899710 58899790 81 - 1.413 1.344 -0.237
ENSG00000137776 E049 25.2515634 0.0035066318 1.139927e-01 0.3555437122 15 58899791 58899880 90 - 1.466 1.368 -0.338
ENSG00000137776 E050 12.7711233 0.0133596886 6.904898e-02 0.2655131488 15 58899881 58899883 3 - 1.216 1.048 -0.603
ENSG00000137776 E051 15.5942469 0.0009051572 1.032579e-01 0.3359137478 15 58899884 58899937 54 - 1.276 1.158 -0.414
ENSG00000137776 E052 5.0686404 0.1569673380 3.570436e-01 0.6467870419 15 58900417 58900758 342 - 0.687 0.858 0.684
ENSG00000137776 E053 2.7173579 0.0564084755 2.550117e-01 0.5469577723 15 58900968 58901259 292 - 0.467 0.651 0.848
ENSG00000137776 E054 23.4117801 0.0005772217 1.165719e-01 0.3601695571 15 58901260 58901287 28 - 1.432 1.339 -0.322
ENSG00000137776 E055 26.2226997 0.0005143089 6.628558e-01 0.8594862341 15 58912563 58912610 48 - 1.421 1.448 0.094
ENSG00000137776 E056 15.3855488 0.0010689763 2.064144e-05 0.0006343449 15 58912611 58913252 642 - 1.018 1.344 1.164
ENSG00000137776 E057 28.9014458 0.0005098256 8.631420e-01 0.9527383722 15 58913499 58913556 58 - 1.470 1.481 0.040
ENSG00000137776 E058 40.9868861 0.0020388979 6.437100e-02 0.2555601959 15 58913557 58913696 140 - 1.666 1.577 -0.305
ENSG00000137776 E059 0.6253903 0.0141421939 1.654726e-01 0.4352245377 15 58913697 58913776 80 - 0.094 0.299 2.040
ENSG00000137776 E060 2.2155065 0.0063961754 6.075533e-01 0.8291532988 15 58916574 58916934 361 - 0.467 0.542 0.362
ENSG00000137776 E061 23.5611603 0.0005896711 1.667656e-03 0.0221753821 15 58916935 58916999 65 - 1.477 1.287 -0.657
ENSG00000137776 E062 0.6071708 0.2238179389 6.988361e-01 0.8772773157 15 58917000 58917020 21 - 0.236 0.175 -0.544
ENSG00000137776 E063 0.9969502 0.1472160995 2.103188e-01 0.4947803130 15 58921446 58921584 139 - 0.171 0.396 1.625
ENSG00000137776 E064 0.7349036 0.0141795426 9.779686e-01 0.9968441005 15 58932152 58932355 204 - 0.237 0.242 0.040
ENSG00000137776 E065 18.8720721 0.0085938259 1.340116e-01 0.3889668074 15 58932356 58932443 88 - 1.352 1.240 -0.391
ENSG00000137776 E066 0.6096837 0.2935744120 8.291787e-01 0.9382316300 15 58933050 58933140 91 - 0.237 0.175 -0.546
ENSG00000137776 E067 17.7032140 0.0008512829 4.399609e-01 0.7157807836 15 58933404 58933730 327 - 1.297 1.246 -0.179

Help

Please Click HERE to learn more details about the results from DEXseq.