ENSG00000137825

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000260386 ENSG00000137825 No_inf pgKDN_inf ITPKA protein_coding protein_coding 0.9059203 1.452639 0.5019388 0.154976 0.1847719 -1.51453 0.2216944 0.1631445 0.5019388 0.05990661 0.1847719 1.563995 0.3140273 0.113575 1 0.886425 0.01375742 0.01375742 FALSE TRUE
ENST00000425927 ENSG00000137825 No_inf pgKDN_inf ITPKA protein_coding protein_coding 0.9059203 1.452639 0.5019388 0.154976 0.1847719 -1.51453 0.1712305 0.5136915 0.0000000 0.36941821 0.0000000 -5.710645 0.1198636 0.329625 0 -0.329625 0.86121426 0.01375742 FALSE FALSE
ENST00000462816 ENSG00000137825 No_inf pgKDN_inf ITPKA protein_coding retained_intron 0.9059203 1.452639 0.5019388 0.154976 0.1847719 -1.51453 0.5129954 0.7758031 0.0000000 0.30952142 0.0000000 -6.296096 0.5661091 0.556800 0 -0.556800 0.44605511 0.01375742 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137825 E001 0.0000000       15 41493393 41493494 102 +      
ENSG00000137825 E002 0.8333113 0.01941497 0.001088659 0.01598577 15 41493874 41494272 399 + 0.518 0.063 -3.879
ENSG00000137825 E003 0.7318536 0.01842094 0.240166929 0.52942295 15 41494273 41494416 144 + 0.332 0.167 -1.294
ENSG00000137825 E004 0.1272623 2.14761229 0.798831861   15 41501439 41501462 24 + 0.000 0.063 8.160
ENSG00000137825 E005 1.1232385 0.01361824 0.709997303 0.88269316 15 41501463 41501559 97 + 0.247 0.321 0.514
ENSG00000137825 E006 1.3780455 0.01059886 0.424071504 0.70325224 15 41501635 41501793 159 + 0.247 0.381 0.876
ENSG00000137825 E007 0.7520260 0.01468073 0.641154823 0.84763321 15 41501794 41501851 58 + 0.141 0.251 1.028
ENSG00000137825 E008 0.9880774 0.01360619 0.554887937 0.79763662 15 41501997 41502201 205 + 0.332 0.251 -0.557
ENSG00000137825 E009 0.8786867 0.06545165 0.480983396 0.74618791 15 41502402 41502503 102 + 0.141 0.287 1.291
ENSG00000137825 E010 0.0000000       15 41502504 41502645 142 +      
ENSG00000137825 E011 1.0060136 0.01251937 0.334376336 0.62619582 15 41502788 41502859 72 + 0.141 0.321 1.514
ENSG00000137825 E012 1.7412921 0.01087070 1.000000000 1.00000000 15 41502963 41503551 589 + 0.404 0.409 0.028

Help

Please Click HERE to learn more details about the results from DEXseq.