ENSG00000137996

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370128 ENSG00000137996 No_inf pgKDN_inf RTCA protein_coding protein_coding 43.77496 30.72935 54.96528 0.4472785 1.864863 0.8386962 35.539220 22.318584 45.223679 1.259503 1.766497 1.018506 0.80284167 0.725150 0.827975 0.102825 0.52854793 0.01368589 FALSE TRUE
ENST00000498617 ENSG00000137996 No_inf pgKDN_inf RTCA protein_coding protein_coding_CDS_not_defined 43.77496 30.72935 54.96528 0.4472785 1.864863 0.8386962 4.013940 1.459187 7.719717 1.459187 3.335305 2.395398 0.08100833 0.046075 0.134850 0.088775 0.39636526 0.01368589 FALSE FALSE
MSTRG.1416.1 ENSG00000137996 No_inf pgKDN_inf RTCA protein_coding   43.77496 30.72935 54.96528 0.4472785 1.864863 0.8386962 1.302543 3.907628 0.000000 1.717724 0.000000 -8.613837 0.04305833 0.129175 0.000000 -0.129175 0.01368589 0.01368589 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000137996 E001 0.4822993 0.0298982770 0.530303089   1 100266216 100266245 30 + 0.207 0.112 -1.048
ENSG00000137996 E002 0.4822993 0.0298982770 0.530303089   1 100266246 100266248 3 + 0.207 0.112 -1.048
ENSG00000137996 E003 0.4822993 0.0298982770 0.530303089   1 100266249 100266264 16 + 0.207 0.112 -1.048
ENSG00000137996 E004 5.9538393 0.0023543398 0.761204688 0.90678771 1 100266265 100266288 24 + 0.851 0.820 -0.122
ENSG00000137996 E005 24.7919728 0.0005717216 0.014504545 0.10270292 1 100266289 100266420 132 + 1.463 1.317 -0.506
ENSG00000137996 E006 31.5409288 0.0025743344 0.005473223 0.05285458 1 100266524 100266624 101 + 1.568 1.411 -0.538
ENSG00000137996 E007 0.4890031 0.0160566833 0.715936149   1 100266625 100266929 305 + 0.148 0.201 0.537
ENSG00000137996 E008 0.6151966 0.3492731997 0.600716658 0.82521948 1 100267166 100267245 80 + 0.148 0.275 1.123
ENSG00000137996 E009 0.9963846 0.0115256616 0.052921375 0.22867020 1 100267500 100267538 39 + 0.148 0.442 2.122
ENSG00000137996 E010 2.6219068 0.0388670209 0.002915033 0.03380826 1 100268074 100268136 63 + 0.304 0.757 2.215
ENSG00000137996 E011 2.2509771 0.0081475466 0.001730432 0.02283560 1 100268137 100268151 15 + 0.258 0.710 2.344
ENSG00000137996 E012 44.8097744 0.0005448601 0.020611299 0.12933680 1 100268152 100268295 144 + 1.697 1.595 -0.348
ENSG00000137996 E013 51.0887127 0.0003284707 0.004554835 0.04639480 1 100270557 100270680 124 + 1.758 1.641 -0.397
ENSG00000137996 E014 28.6525638 0.0004937887 0.308927373 0.60227526 1 100273394 100273452 59 + 1.490 1.435 -0.187
ENSG00000137996 E015 66.7840094 0.0002403236 0.145166133 0.40545781 1 100274824 100274965 142 + 1.847 1.797 -0.170
ENSG00000137996 E016 68.3733682 0.0002273758 0.270502980 0.56420867 1 100275599 100275723 125 + 1.818 1.859 0.138
ENSG00000137996 E017 48.1475000 0.0078894115 0.055219054 0.23413400 1 100277258 100277316 59 + 1.638 1.745 0.361
ENSG00000137996 E018 26.7297434 0.0008919383 0.003055028 0.03494589 1 100285228 100285239 12 + 1.357 1.528 0.590
ENSG00000137996 E019 59.4866944 0.0002726937 0.247337265 0.53794209 1 100285240 100285322 83 + 1.757 1.803 0.156
ENSG00000137996 E020 62.4650418 0.0002535831 0.490830480 0.75333789 1 100287099 100287203 105 + 1.808 1.784 -0.079
ENSG00000137996 E021 163.2314505 0.0001257506 0.029156522 0.16022163 1 100291403 100292769 1367 + 2.189 2.238 0.162

Help

Please Click HERE to learn more details about the results from DEXseq.