ENSG00000138035

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415374 ENSG00000138035 No_inf pgKDN_inf PNPT1 protein_coding nonsense_mediated_decay 16.23027 10.99642 18.80802 0.9131701 0.6089302 0.7737693 7.1490003 1.873449 10.833589 0.6668550 0.9875381 2.5253939 0.40005833 0.169450 0.5736 0.404150 0.04472409 0.01109369 TRUE TRUE
ENST00000447944 ENSG00000138035 No_inf pgKDN_inf PNPT1 protein_coding protein_coding 16.23027 10.99642 18.80802 0.9131701 0.6089302 0.7737693 4.0131648 4.210888 3.201794 0.2603685 0.4626388 -0.3941674 0.26898333 0.385150 0.1718 -0.213350 0.13212046 0.01109369 FALSE TRUE
ENST00000481066 ENSG00000138035 No_inf pgKDN_inf PNPT1 protein_coding retained_intron 16.23027 10.99642 18.80802 0.9131701 0.6089302 0.7737693 0.9922054 2.976616 0.000000 1.2487957 0.0000000 -8.2223681 0.08266667 0.248000 0.0000 -0.248000 0.01109369 0.01109369   FALSE
MSTRG.16303.5 ENSG00000138035 No_inf pgKDN_inf PNPT1 protein_coding   16.23027 10.99642 18.80802 0.9131701 0.6089302 0.7737693 3.5836091 1.288323 3.942924 0.8040712 0.5240754 1.6062708 0.21315000 0.136275 0.2103 0.074025 0.66580429 0.01109369 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138035 E001 0.6081183 0.2409597696 8.565321e-01 9.496012e-01 2 55634061 55634117 57 - 0.186 0.223 0.327
ENSG00000138035 E002 10.0935563 0.0014092866 3.261131e-05 9.262024e-04 2 55634118 55634568 451 - 0.860 1.225 1.338
ENSG00000138035 E003 5.1364937 0.0094573719 1.016245e-01 3.328584e-01 2 55634569 55634849 281 - 0.692 0.887 0.775
ENSG00000138035 E004 4.2860319 0.0385503461 1.435699e-01 4.035255e-01 2 55634850 55635093 244 - 0.624 0.827 0.830
ENSG00000138035 E005 8.4248929 0.0016289082 1.528925e-07 8.545188e-06 2 55635094 55635561 468 - 0.708 1.207 1.881
ENSG00000138035 E006 30.5894989 0.0004999547 2.617268e-01 5.544809e-01 2 55635562 55636369 808 - 1.460 1.522 0.212
ENSG00000138035 E007 8.1303204 0.0017786291 6.671080e-01 8.615259e-01 2 55636370 55636392 23 - 0.929 0.973 0.164
ENSG00000138035 E008 13.1148215 0.0011977180 3.731278e-01 6.608740e-01 2 55637552 55637599 48 - 1.106 1.179 0.260
ENSG00000138035 E009 18.7503780 0.0094624194 8.928726e-01 9.645020e-01 2 55640627 55640705 79 - 1.283 1.274 -0.032
ENSG00000138035 E010 15.9209604 0.0009086361 2.717943e-01 5.655679e-01 2 55643158 55643213 56 - 1.241 1.159 -0.289
ENSG00000138035 E011 20.1573494 0.0008644048 3.147837e-01 6.076605e-01 2 55643319 55643412 94 - 1.333 1.266 -0.233
ENSG00000138035 E012 9.2795328 0.0018793355 2.477466e-01 5.384850e-01 2 55643413 55643425 13 - 1.034 0.924 -0.410
ENSG00000138035 E013 15.1002674 0.0011001286 5.099111e-01 7.675568e-01 2 55644637 55644720 84 - 1.209 1.159 -0.175
ENSG00000138035 E014 2.9936520 0.0051807215 7.055504e-05 1.767448e-03 2 55644721 55645348 628 - 0.316 0.848 2.497
ENSG00000138035 E015 18.6893035 0.0009575808 4.533265e-01 7.261356e-01 2 55645349 55645432 84 - 1.258 1.311 0.185
ENSG00000138035 E016 17.3938209 0.0008101617 3.637760e-01 6.526254e-01 2 55646259 55646322 64 - 1.271 1.207 -0.225
ENSG00000138035 E017 16.2196685 0.0008848810 8.923565e-03 7.452517e-02 2 55646415 55646486 72 - 1.283 1.082 -0.716
ENSG00000138035 E018 12.2621451 0.0011233813 4.265640e-02 2.012824e-01 2 55647347 55647400 54 - 1.163 0.988 -0.635
ENSG00000138035 E019 12.6497689 0.0012475578 1.737295e-01 4.471665e-01 2 55647401 55647453 53 - 1.158 1.044 -0.410
ENSG00000138035 E020 0.2372762 0.2571368405 6.107793e-01   2 55654454 55654500 47 - 0.133 0.000 -9.109
ENSG00000138035 E021 11.1963883 0.0025473927 1.642755e-01 4.335504e-01 2 55654900 55654953 54 - 1.112 0.988 -0.453
ENSG00000138035 E022 10.8653779 0.0018849147 3.353552e-01 6.272443e-01 2 55656131 55656220 90 - 1.088 1.003 -0.310
ENSG00000138035 E023 10.1848958 0.0016503535 8.606004e-01 9.516858e-01 2 55656305 55656371 67 - 1.027 1.044 0.064
ENSG00000138035 E024 10.0166547 0.0014520913 3.665489e-01 6.552537e-01 2 55660157 55660193 37 - 1.055 0.973 -0.302
ENSG00000138035 E025 10.2304518 0.0013927081 1.271852e-01 3.781065e-01 2 55661956 55662026 71 - 1.081 0.941 -0.518
ENSG00000138035 E026 15.0717818 0.0009047150 2.149498e-01 5.005656e-01 2 55666991 55667093 103 - 1.223 1.128 -0.338
ENSG00000138035 E027 11.9315861 0.0013593706 1.484463e-01 4.103289e-01 2 55667862 55667958 97 - 1.048 1.169 0.437
ENSG00000138035 E028 9.5824021 0.0015946061 7.222201e-01 8.883174e-01 2 55671319 55671376 58 - 0.997 1.031 0.126
ENSG00000138035 E029 8.6003673 0.0093068580 9.434039e-01 9.843024e-01 2 55671995 55672046 52 - 0.964 0.973 0.033
ENSG00000138035 E030 13.6451434 0.0024490844 2.938011e-01 5.872972e-01 2 55672893 55673079 187 - 1.179 1.094 -0.304
ENSG00000138035 E031 12.0366372 0.0013365198 3.407082e-01 6.323384e-01 2 55679682 55679795 114 - 1.068 1.149 0.291
ENSG00000138035 E032 6.3051562 0.0094117312 7.961183e-01 9.227198e-01 2 55680712 55680759 48 - 0.838 0.868 0.116
ENSG00000138035 E033 0.0000000       2 55680760 55680854 95 -      
ENSG00000138035 E034 5.0846585 0.0028325805 8.987092e-01 9.667235e-01 2 55680855 55680918 64 - 0.765 0.781 0.064
ENSG00000138035 E035 5.0732294 0.0027874439 6.002725e-01 8.249101e-01 2 55683785 55683834 50 - 0.791 0.730 -0.245
ENSG00000138035 E036 6.8858304 0.0021621310 6.099391e-01 8.303202e-01 2 55684943 55684993 51 - 0.901 0.848 -0.203
ENSG00000138035 E037 6.8851703 0.0111836703 6.254506e-01 8.389012e-01 2 55684994 55685048 55 - 0.901 0.848 -0.203
ENSG00000138035 E038 6.2903696 0.0023739858 9.817207e-01 9.982866e-01 2 55686370 55686444 75 - 0.849 0.848 -0.005
ENSG00000138035 E039 4.9565434 0.0150549786 9.487539e-01 9.867620e-01 2 55687645 55687705 61 - 0.765 0.756 -0.035
ENSG00000138035 E040 6.1873779 0.0023034675 7.148828e-01 8.850940e-01 2 55693663 55693863 201 - 0.827 0.868 0.160

Help

Please Click HERE to learn more details about the results from DEXseq.