ENSG00000138073

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000260643 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding protein_coding 41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 26.231867 20.0801411 29.5796853 1.6279430 0.6793927 0.5586067 0.64476667 0.568000 0.721975 0.153975 0.33246649 0.02362263 FALSE  
ENST00000430533 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding protein_coding 41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 3.585020 0.7946534 6.0210694 0.7946534 3.6907024 2.9059745 0.07705000 0.023025 0.128025 0.105000 0.78380254 0.02362263 FALSE  
ENST00000441451 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding nonsense_mediated_decay 41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 2.866528 3.7930585 0.3758361 1.4249656 0.3758361 -3.3011001 0.06897500 0.104900 0.007800 -0.097100 0.23043551 0.02362263    
ENST00000456259 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding protein_coding 41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 1.188553 3.2694051 0.0000000 1.1800176 0.0000000 -8.3572903 0.03335000 0.092650 0.000000 -0.092650 0.02362263 0.02362263 FALSE  
MSTRG.15979.5 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding   41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 1.936476 2.3512255 0.2907136 2.3512255 0.2907136 -2.9730738 0.04405000 0.064300 0.006450 -0.057850 1.00000000 0.02362263    
MSTRG.15979.7 ENSG00000138073 No_inf pgKDN_inf PREB protein_coding   41.01556 35.40632 41.59614 1.261494 3.18516 0.2323821 2.279464 3.2570452 1.4635434 0.6814787 0.8611720 -1.1486969 0.05931667 0.092625 0.037050 -0.055575 0.50207963 0.02362263 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138073 E001 0.0000000       2 27130756 27130762 7 -      
ENSG00000138073 E002 0.0000000       2 27130763 27130764 2 -      
ENSG00000138073 E003 0.0000000       2 27130765 27130768 4 -      
ENSG00000138073 E004 0.0000000       2 27130769 27130774 6 -      
ENSG00000138073 E005 0.0000000       2 27130775 27130790 16 -      
ENSG00000138073 E006 58.6769559 0.0003018853 0.021861626 0.13421570 2 27130791 27131158 368 - 1.731 1.817 0.292
ENSG00000138073 E007 74.0170013 0.0004012212 0.318262741 0.61103455 2 27131159 27131439 281 - 1.891 1.859 -0.109
ENSG00000138073 E008 30.7339437 0.0018051863 0.602094059 0.82618855 2 27131440 27131508 69 - 1.487 1.516 0.099
ENSG00000138073 E009 13.5975308 0.0073542096 0.652259814 0.85349549 2 27131672 27131673 2 - 1.145 1.183 0.137
ENSG00000138073 E010 37.4689313 0.0037641345 0.042647805 0.20128240 2 27131674 27131831 158 - 1.528 1.636 0.367
ENSG00000138073 E011 1.1971493 0.0117853158 0.068094609 0.26323213 2 27131832 27132009 178 - 0.460 0.179 -1.889
ENSG00000138073 E012 22.4006228 0.0006412779 0.661118037 0.85855723 2 27132010 27132082 73 - 1.355 1.383 0.095
ENSG00000138073 E013 0.7533131 0.0144913836 0.077379650 0.28456253 2 27132204 27132229 26 - 0.092 0.356 2.433
ENSG00000138073 E014 34.2141700 0.0004339490 0.738405009 0.89623584 2 27132230 27132339 110 - 1.555 1.539 -0.054
ENSG00000138073 E015 23.1809655 0.0005889454 0.425920231 0.70481543 2 27132340 27132403 64 - 1.407 1.359 -0.164
ENSG00000138073 E016 0.1170040 0.0116974989 0.579449082   2 27132511 27132602 92 - 0.092 0.000 -9.075
ENSG00000138073 E017 42.8742340 0.0013345638 0.051418207 0.22473173 2 27132603 27132727 125 - 1.684 1.596 -0.302
ENSG00000138073 E018 29.4434206 0.0004921917 0.697785992 0.87664546 2 27132843 27132923 81 - 1.493 1.473 -0.069
ENSG00000138073 E019 16.3029539 0.0008502710 0.487148414 0.75076759 2 27133117 27133123 7 - 1.212 1.262 0.176
ENSG00000138073 E020 47.0146525 0.0009458206 0.522826120 0.77625128 2 27133124 27133337 214 - 1.667 1.695 0.096
ENSG00000138073 E021 6.3142682 0.0022113089 0.018062794 0.11860223 2 27133338 27133531 194 - 0.719 0.973 0.985
ENSG00000138073 E022 24.8656197 0.0014728422 0.322679576 0.61559196 2 27133532 27133654 123 - 1.441 1.383 -0.202
ENSG00000138073 E023 15.6253301 0.0011745392 0.647504321 0.85106964 2 27133655 27133721 67 - 1.237 1.204 -0.115
ENSG00000138073 E024 9.8091115 0.0291595118 0.522609617 0.77603665 2 27133722 27134286 565 - 0.998 1.068 0.255
ENSG00000138073 E025 31.8372766 0.0013926052 0.004482298 0.04590738 2 27134287 27134666 380 - 1.585 1.435 -0.516

Help

Please Click HERE to learn more details about the results from DEXseq.