ENSG00000138074

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310574 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding protein_coding 45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 6.031031 2.0221699 6.177077 0.8140639 1.9820207 1.6062369 0.12588333 0.11630 0.114975 -0.001325 1.00000000 0.02085688 FALSE TRUE
ENST00000461757 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding retained_intron 45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 1.901954 1.6086138 1.221602 0.2697406 0.3461493 -0.3942224 0.05323333 0.09370 0.023075 -0.070625 0.18547833 0.02085688 FALSE FALSE
ENST00000488743 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding retained_intron 45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 2.177820 1.4554547 2.143852 0.6165578 0.2790908 0.5555707 0.05621667 0.08490 0.040075 -0.044825 0.78134899 0.02085688 TRUE TRUE
MSTRG.15982.3 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding   45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 15.529251 2.1463299 21.386039 1.6234523 3.0834956 3.3106939 0.28959167 0.12460 0.396625 0.272025 0.14544593 0.02085688 FALSE TRUE
MSTRG.15982.5 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding   45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 6.607145 0.8646828 8.961003 0.8646828 1.6938659 3.3584375 0.12198333 0.04985 0.167125 0.117275 0.13371308 0.02085688 FALSE TRUE
MSTRG.15982.7 ENSG00000138074 No_inf pgKDN_inf SLC5A6 protein_coding   45.94635 17.16134 53.8497 0.2640706 1.212671 1.649203 6.737262 5.7255174 6.928295 0.5520160 0.4698913 0.2746575 0.19265000 0.33470 0.128875 -0.205825 0.02085688 0.02085688 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138074 E001 0.1271363 0.0124477878 1.549661e-01   2 27199587 27199587 1 - 0.000 0.153 11.392
ENSG00000138074 E002 0.4893505 0.0158814936 2.881880e-01   2 27199588 27199588 1 - 0.108 0.266 1.576
ENSG00000138074 E003 1.6781343 0.0092368683 7.380809e-01 0.8960715634 2 27199589 27199613 25 - 0.408 0.356 -0.298
ENSG00000138074 E004 42.3095324 0.0003914158 2.075718e-01 0.4911275157 2 27199614 27199837 224 - 1.565 1.632 0.229
ENSG00000138074 E005 77.0037365 0.0003000190 5.026673e-01 0.7622689793 2 27199838 27200104 267 - 1.831 1.860 0.098
ENSG00000138074 E006 60.4475546 0.0004240656 1.006769e-01 0.3312130188 2 27200105 27200435 331 - 1.752 1.684 -0.231
ENSG00000138074 E007 33.1176304 0.0009839243 2.743334e-01 0.5678717141 2 27200436 27200579 144 - 1.496 1.435 -0.211
ENSG00000138074 E008 31.6341676 0.0072191539 7.679701e-01 0.9102333920 2 27200998 27201101 104 - 1.455 1.480 0.085
ENSG00000138074 E009 16.1549819 0.0010059174 3.194989e-01 0.6121735984 2 27201102 27201113 12 - 1.160 1.243 0.292
ENSG00000138074 E010 2.9434599 0.0050010263 2.915532e-03 0.0338082620 2 27201114 27201349 236 - 0.408 0.813 1.818
ENSG00000138074 E011 23.3579621 0.0006021496 6.296921e-01 0.8411825946 2 27201350 27201411 62 - 1.325 1.361 0.127
ENSG00000138074 E012 23.2373473 0.0005872248 5.985017e-01 0.8240054965 2 27201412 27201453 42 - 1.322 1.361 0.137
ENSG00000138074 E013 2.2153781 0.0303347590 1.040153e-02 0.0823944176 2 27201454 27201665 212 - 0.329 0.718 1.898
ENSG00000138074 E014 26.4783284 0.0057697399 8.367996e-01 0.9415181996 2 27201666 27201711 46 - 1.382 1.400 0.060
ENSG00000138074 E015 29.7558880 0.0004680683 2.476258e-01 0.5383516536 2 27201712 27201783 72 - 1.453 1.385 -0.235
ENSG00000138074 E016 24.1990425 0.0008388391 6.453574e-02 0.2560355675 2 27201784 27201847 64 - 1.380 1.253 -0.441
ENSG00000138074 E017 0.2543986 0.0160500531 3.960816e-02   2 27201848 27201987 140 - 0.000 0.266 15.080
ENSG00000138074 E018 23.6556876 0.0018605853 3.402560e-01 0.6319015901 2 27201988 27202070 83 - 1.356 1.292 -0.222
ENSG00000138074 E019 9.0230028 0.0414278127 8.880601e-01 0.9625638906 2 27202071 27202074 4 - 0.958 0.935 -0.088
ENSG00000138074 E020 17.0253963 0.0324896167 2.732789e-01 0.5670382234 2 27202813 27202880 68 - 1.235 1.108 -0.450
ENSG00000138074 E021 7.7199048 0.0833936702 7.200743e-03 0.0642775338 2 27202881 27203158 278 - 0.732 1.162 1.622
ENSG00000138074 E022 3.6656126 0.2202464896 2.398939e-01 0.5290280832 2 27203159 27203232 74 - 0.514 0.840 1.383
ENSG00000138074 E023 23.4843393 0.0014252147 6.620469e-01 0.8590374560 2 27203233 27203345 113 - 1.328 1.361 0.117
ENSG00000138074 E024 19.0871184 0.0007182530 5.526420e-01 0.7961268987 2 27203779 27203867 89 - 1.262 1.221 -0.145
ENSG00000138074 E025 22.2789035 0.0055326699 1.485270e-01 0.4104869472 2 27204461 27204590 130 - 1.342 1.232 -0.385
ENSG00000138074 E026 0.4904501 0.0157984903 2.887946e-01   2 27204591 27204672 82 - 0.108 0.266 1.576
ENSG00000138074 E027 24.9019192 0.0005454884 7.920622e-01 0.9205508061 2 27204791 27204931 141 - 1.356 1.377 0.074
ENSG00000138074 E028 10.0516874 0.0135848131 2.499452e-06 0.0001028012 2 27204932 27205134 203 - 0.815 1.283 1.717
ENSG00000138074 E029 8.6508896 0.0017215695 8.444292e-04 0.0131666508 2 27205135 27205349 215 - 0.824 1.149 1.209
ENSG00000138074 E030 12.9715571 0.0024160763 2.106434e-02 0.1311509420 2 27205350 27205406 57 - 1.033 1.232 0.716
ENSG00000138074 E031 8.4995187 0.0066395920 3.528970e-02 0.1798211577 2 27205407 27205411 5 - 0.860 1.079 0.817
ENSG00000138074 E032 16.7974202 0.0101127631 1.254573e-01 0.3754852390 2 27205412 27205504 93 - 1.160 1.292 0.466
ENSG00000138074 E033 13.9019328 0.0111548715 5.303089e-01 0.7814453392 2 27206026 27206093 68 - 1.138 1.079 -0.214
ENSG00000138074 E034 1.4604645 0.0262106016 2.282416e-01 0.5167886038 2 27206094 27206319 226 - 0.299 0.493 1.091
ENSG00000138074 E035 13.7648193 0.0205351037 3.690730e-01 0.6574438710 2 27206483 27206534 52 - 1.143 1.047 -0.345
ENSG00000138074 E036 8.8655672 0.0033194728 4.663624e-01 0.7350747346 2 27206877 27206893 17 - 0.965 0.890 -0.281
ENSG00000138074 E037 12.1978768 0.0063862544 1.251692e-01 0.3750425133 2 27206894 27206936 43 - 1.106 0.956 -0.551
ENSG00000138074 E038 7.9947097 0.0023655935 4.036277e-02 0.1948206438 2 27206937 27206942 6 - 0.958 0.718 -0.934
ENSG00000138074 E039 13.4657326 0.0018169649 1.795947e-03 0.0235139135 2 27207258 27207303 46 - 1.173 0.866 -1.131
ENSG00000138074 E040 19.8875795 0.0012364959 1.003885e-01 0.3308838463 2 27207304 27207414 111 - 1.298 1.175 -0.434
ENSG00000138074 E041 11.1651036 0.0064914808 7.233346e-01 0.8888862472 2 27207415 27207474 60 - 1.044 1.013 -0.114
ENSG00000138074 E042 11.2223975 0.0060712745 6.434369e-02 0.2554705937 2 27207475 27207534 60 - 1.081 0.890 -0.709
ENSG00000138074 E043 7.4155231 0.0020284258 2.715765e-01 0.5653054405 2 27207535 27207569 35 - 0.908 0.783 -0.482
ENSG00000138074 E044 19.8734490 0.0059791016 8.696052e-02 0.3055657653 2 27207570 27207790 221 - 1.301 1.162 -0.489
ENSG00000138074 E045 0.5917516 0.0379774129 2.385044e-01 0.5274950936 2 27208394 27208448 55 - 0.233 0.000 -14.645
ENSG00000138074 E046 0.5001731 0.0376464636 4.114355e-02 0.1968325569 2 27208614 27208686 73 - 0.058 0.356 3.161
ENSG00000138074 E047 8.0509110 0.0091208900 5.981528e-01 0.8237969372 2 27211467 27211533 67 - 0.923 0.866 -0.217
ENSG00000138074 E048 0.1186381 0.0118658216 1.000000e+00   2 27211711 27211766 56 - 0.058 0.000 -12.558
ENSG00000138074 E049 0.7076180 0.0134021497 1.575231e-01 0.4241355720 2 27211767 27211899 133 - 0.267 0.000 -14.922
ENSG00000138074 E050 1.9168883 0.0071283593 5.369816e-01 0.7861261427 2 27211900 27212019 120 - 0.454 0.356 -0.539
ENSG00000138074 E051 0.3544103 0.0305696372 5.570674e-01   2 27212020 27212146 127 - 0.154 0.000 -14.001
ENSG00000138074 E052 0.0000000       2 27212147 27212268 122 -      
ENSG00000138074 E053 0.0000000       2 27212463 27212522 60 -      
ENSG00000138074 E054 0.8618152 0.5317533277 2.029773e-01 0.4856219886 2 27212629 27212831 203 - 0.154 0.430 1.994
ENSG00000138074 E055 0.2545247 0.2286296636 6.000062e-02   2 27212832 27212958 127 - 0.000 0.266 14.332

Help

Please Click HERE to learn more details about the results from DEXseq.