ENSG00000138166

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369583 ENSG00000138166 No_inf pgKDN_inf DUSP5 protein_coding protein_coding 23.05519 4.572717 31.19819 0.2027588 0.4790648 2.76765 11.75278 0.7729224 16.92149 0.2456704 0.7492586 4.434696 0.4151917 0.173975 0.543425 0.36945 0.010123421 0.009748995 FALSE TRUE
ENST00000468749 ENSG00000138166 No_inf pgKDN_inf DUSP5 protein_coding protein_coding_CDS_not_defined 23.05519 4.572717 31.19819 0.2027588 0.4790648 2.76765 11.30241 3.7997943 14.27670 0.3965797 1.1141577 1.906888 0.5848083 0.826025 0.456575 -0.36945 0.009748995 0.009748995 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138166 E001 14.9199877 0.0009027219 0.001539725 0.02086521 10 110497907 110498500 594 + 1.091 0.682 -1.575
ENSG00000138166 E002 5.0769718 0.0030944177 0.012652805 0.09357162 10 110502721 110502746 26 + 0.696 0.213 -2.646
ENSG00000138166 E003 11.2561108 0.0012793802 0.011308572 0.08720568 10 110502747 110502869 123 + 0.978 0.620 -1.423
ENSG00000138166 E004 0.2459004 0.0164935643 0.135522003   10 110503433 110503490 58 + 0.039 0.213 2.745
ENSG00000138166 E005 19.2382527 0.0008527653 0.137700177 0.39499900 10 110506935 110507154 220 + 1.135 1.258 0.435
ENSG00000138166 E006 134.8979853 0.0001802211 0.008732790 0.07336903 10 110510020 110511533 1514 + 1.967 2.013 0.156

Help

Please Click HERE to learn more details about the results from DEXseq.