ENSG00000138172

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369788 ENSG00000138172 No_inf pgKDN_inf CALHM2 protein_coding protein_coding 41.90611 44.74486 46.47575 1.197282 0.9191569 0.05474425 11.081104 15.709564 9.095178 2.5943766 2.009379 -0.7878020 0.26504167 0.350250 0.197275 -0.152975 0.3827237 0.0330261 FALSE  
MSTRG.3938.1 ENSG00000138172 No_inf pgKDN_inf CALHM2 protein_coding   41.90611 44.74486 46.47575 1.197282 0.9191569 0.05474425 7.365165 7.837666 6.219902 3.7791541 1.370157 -0.3330542 0.18386667 0.182175 0.135350 -0.046825 0.9883420 0.0330261 FALSE  
MSTRG.3938.14 ENSG00000138172 No_inf pgKDN_inf CALHM2 protein_coding   41.90611 44.74486 46.47575 1.197282 0.9191569 0.05474425 9.045256 6.792024 13.466718 2.3896611 1.852475 0.9864332 0.21120833 0.149125 0.289025 0.139900 0.6230479 0.0330261 FALSE  
MSTRG.3938.15 ENSG00000138172 No_inf pgKDN_inf CALHM2 protein_coding   41.90611 44.74486 46.47575 1.197282 0.9191569 0.05474425 1.545280 0.000000 4.061296 0.0000000 1.847692 8.6693442 0.03415833 0.000000 0.085875 0.085875 0.0330261 0.0330261 FALSE  
MSTRG.3938.7 ENSG00000138172 No_inf pgKDN_inf CALHM2 protein_coding   41.90611 44.74486 46.47575 1.197282 0.9191569 0.05474425 8.456181 7.976448 9.412351 0.2659877 1.046160 0.2385331 0.20336667 0.178825 0.201725 0.022900 0.8877611 0.0330261 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138172 E001 0.3812526 0.0158914953 0.13554930   10 103446763 103446785 23 - 0.000 0.226 10.713
ENSG00000138172 E002 0.9895205 0.0120178205 0.62237010 0.83732729 10 103446786 103446797 12 - 0.253 0.330 0.523
ENSG00000138172 E003 1.4794326 0.0101441611 0.75421030 0.90329593 10 103446798 103446834 37 - 0.365 0.413 0.272
ENSG00000138172 E004 3.8362995 0.0160251970 0.25142046 0.54257807 10 103446835 103446835 1 - 0.591 0.744 0.649
ENSG00000138172 E005 182.8770850 0.0001191244 0.84745473 0.94593351 10 103446836 103447568 733 - 2.259 2.264 0.018
ENSG00000138172 E006 16.3264438 0.0010433037 0.02234400 0.13594246 10 103449387 103449399 13 - 1.135 1.303 0.594
ENSG00000138172 E007 76.4593862 0.0002855716 0.06074887 0.24741213 10 103449400 103449624 225 - 1.850 1.913 0.212
ENSG00000138172 E008 40.9581491 0.0003592786 0.52368936 0.77680589 10 103449625 103449698 74 - 1.635 1.608 -0.092
ENSG00000138172 E009 75.4795610 0.0002407791 0.00368760 0.04013865 10 103449699 103449934 236 - 1.930 1.837 -0.312
ENSG00000138172 E010 32.9300364 0.0008287032 0.09223067 0.31540004 10 103449935 103450024 90 - 1.573 1.488 -0.289
ENSG00000138172 E011 30.7440363 0.0020182139 0.32374639 0.61637359 10 103450025 103450099 75 - 1.527 1.475 -0.179
ENSG00000138172 E012 6.7619215 0.0021450710 0.70368213 0.87947718 10 103450100 103450295 196 - 0.865 0.906 0.156
ENSG00000138172 E013 0.0000000       10 103450296 103450411 116 -      
ENSG00000138172 E014 0.0000000       10 103450412 103450573 162 -      
ENSG00000138172 E015 0.0000000       10 103450574 103450800 227 -      
ENSG00000138172 E016 21.8608572 0.0015101298 0.85135962 0.94739683 10 103451083 103451182 100 - 1.349 1.363 0.047
ENSG00000138172 E017 6.7678214 0.0032755055 0.70530758 0.88024792 10 103451183 103451201 19 - 0.865 0.906 0.156
ENSG00000138172 E018 8.4908370 0.0091204360 0.66953224 0.86262994 10 103451202 103451285 84 - 0.950 0.994 0.165
ENSG00000138172 E019 3.1830910 0.0575919158 0.52006205 0.77459678 10 103451286 103451608 323 - 0.671 0.571 -0.437
ENSG00000138172 E020 2.3674801 0.0817218829 0.13161322 0.38488088 10 103451879 103452036 158 - 0.365 0.622 1.273
ENSG00000138172 E021 24.1498350 0.0193765606 0.31990781 0.61270979 10 103452156 103452545 390 - 1.349 1.434 0.292

Help

Please Click HERE to learn more details about the results from DEXseq.