ENSG00000138443

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261017 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 4.3980585 4.488675 4.4255432 0.3028447 0.2095879 -0.02038945 0.17745833 0.227975 0.166275 -0.061700 0.77032340 0.01153327 FALSE TRUE
ENST00000376135 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding_CDS_not_defined 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 6.9900997 5.332012 6.7198464 1.7886721 2.7396888 0.33319035 0.22941667 0.262300 0.196825 -0.065475 0.93218772 0.01153327 FALSE TRUE
ENST00000416396 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding_CDS_not_defined 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 5.2129631 3.939944 4.8575903 1.3950931 1.6513621 0.30137562 0.19005000 0.202700 0.183150 -0.019550 0.99226958 0.01153327 FALSE FALSE
ENST00000417864 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 0.9756943 0.000000 1.7441670 0.0000000 1.2889315 7.45464231 0.05126667 0.000000 0.090000 0.090000 0.63267546 0.01153327 FALSE TRUE
ENST00000422719 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding_CDS_not_defined 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 5.3198773 0.000000 8.0167863 0.0000000 3.1855063 9.64867868 0.14912500 0.000000 0.248850 0.248850 0.01153327 0.01153327 FALSE FALSE
ENST00000430574 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding_CDS_not_defined 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 2.0030350 2.462866 2.0200057 1.0196158 2.0200057 -0.28470013 0.07328333 0.127175 0.053050 -0.074125 0.43245323 0.01153327 FALSE FALSE
ENST00000451591 ENSG00000138443 No_inf pgKDN_inf ABI2 protein_coding protein_coding 28.02983 19.79974 29.3715 0.6895819 4.70632 0.568698 1.6670053 1.824278 0.4827237 1.8242776 0.4827237 -1.89636119 0.06657500 0.091550 0.017975 -0.073575 0.99403343 0.01153327 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138443 E001 0.5997389 0.0152495162 1.411508e-01 3.997336e-01 2 203328280 203328281 2 + 0.309 0.090 -2.161
ENSG00000138443 E002 2.4410725 0.0076996277 5.085521e-01 7.667588e-01 2 203328282 203328390 109 + 0.585 0.489 -0.451
ENSG00000138443 E003 0.9902148 0.0117226667 5.733436e-01 8.087626e-01 2 203328391 203328391 1 + 0.250 0.334 0.576
ENSG00000138443 E004 0.9902148 0.0117226667 5.733436e-01 8.087626e-01 2 203328392 203328393 2 + 0.250 0.334 0.576
ENSG00000138443 E005 0.9902148 0.0117226667 5.733436e-01 8.087626e-01 2 203328394 203328394 1 + 0.250 0.334 0.576
ENSG00000138443 E006 0.9902148 0.0117226667 5.733436e-01 8.087626e-01 2 203328395 203328398 4 + 0.250 0.334 0.576
ENSG00000138443 E007 0.8630785 0.0125130313 8.079320e-01 9.291044e-01 2 203328399 203328404 6 + 0.250 0.285 0.254
ENSG00000138443 E008 0.8630785 0.0125130313 8.079320e-01 9.291044e-01 2 203328405 203328406 2 + 0.250 0.285 0.254
ENSG00000138443 E009 0.8630785 0.0125130313 8.079320e-01 9.291044e-01 2 203328407 203328457 51 + 0.250 0.285 0.254
ENSG00000138443 E010 0.0000000       2 203328458 203328458 1 +      
ENSG00000138443 E011 0.0000000       2 203328459 203328483 25 +      
ENSG00000138443 E012 1.5869376 0.0087073699 6.508219e-01 8.530117e-01 2 203328484 203328514 31 + 0.449 0.378 -0.384
ENSG00000138443 E013 10.1076508 0.0015483451 5.988903e-02 2.455009e-01 2 203328515 203328631 117 + 1.128 0.959 -0.617
ENSG00000138443 E014 0.1186381 0.0119660931 4.867773e-01   2 203342197 203342230 34 + 0.100 0.000 -11.012
ENSG00000138443 E015 0.2441403 0.0164141512 9.380833e-01   2 203351555 203351678 124 + 0.100 0.090 -0.161
ENSG00000138443 E016 0.0000000       2 203355154 203355324 171 +      
ENSG00000138443 E017 6.4583052 0.0022271416 1.870191e-01 4.648610e-01 2 203366877 203366883 7 + 0.943 0.801 -0.545
ENSG00000138443 E018 7.5801805 0.0019791707 3.681141e-01 6.566342e-01 2 203366884 203366922 39 + 0.980 0.887 -0.348
ENSG00000138443 E019 7.7346879 0.0024660769 9.828221e-01 9.986903e-01 2 203366923 203366996 74 + 0.943 0.936 -0.024
ENSG00000138443 E020 5.7706307 0.0029528723 9.265515e-01 9.779953e-01 2 203366997 203367044 48 + 0.826 0.832 0.023
ENSG00000138443 E021 0.9878254 0.0117593551 5.721527e-01 8.082581e-01 2 203367045 203367419 375 + 0.250 0.334 0.576
ENSG00000138443 E022 0.0000000       2 203374820 203374852 33 +      
ENSG00000138443 E023 0.1265070 0.0124458721 5.938688e-01   2 203375932 203376056 125 + 0.000 0.090 9.769
ENSG00000138443 E024 0.2435110 0.0165633366 9.386811e-01   2 203376057 203376132 76 + 0.100 0.090 -0.161
ENSG00000138443 E025 5.2868757 0.0211456457 6.909236e-01 8.731494e-01 2 203380208 203380225 18 + 0.772 0.817 0.176
ENSG00000138443 E026 7.9632204 0.0475333582 9.620652e-01 9.917057e-01 2 203380226 203380274 49 + 0.955 0.948 -0.027
ENSG00000138443 E027 8.4543007 0.0517148294 9.848401e-01 9.989951e-01 2 203380275 203380307 33 + 0.979 0.970 -0.035
ENSG00000138443 E028 7.5172436 0.0055981924 8.996995e-03 7.495272e-02 2 203380308 203380357 50 + 1.055 0.785 -1.024
ENSG00000138443 E029 5.5760050 0.0780562181 9.877776e-02 3.280155e-01 2 203380358 203380384 27 + 0.943 0.672 -1.069
ENSG00000138443 E030 0.0000000       2 203382189 203382206 18 +      
ENSG00000138443 E031 0.3706447 0.2703588052 7.035430e-01   2 203383247 203383296 50 + 0.100 0.165 0.838
ENSG00000138443 E032 0.0000000       2 203391044 203391045 2 +      
ENSG00000138443 E033 4.9665996 0.0937117009 1.058667e-01 3.406200e-01 2 203391046 203391143 98 + 0.903 0.627 -1.109
ENSG00000138443 E034 0.0000000       2 203394700 203394747 48 +      
ENSG00000138443 E035 0.0000000       2 203394748 203394846 99 +      
ENSG00000138443 E036 0.3544103 0.0245762886 8.646653e-02   2 203395656 203395658 3 + 0.250 0.000 -12.437
ENSG00000138443 E037 8.3487120 0.0022535983 3.273819e-03 3.690246e-02 2 203395659 203395780 122 + 1.102 0.817 -1.068
ENSG00000138443 E038 0.1176306 0.0117823942 4.868931e-01   2 203396785 203396883 99 + 0.100 0.000 -11.013
ENSG00000138443 E039 0.0000000       2 203396884 203396967 84 +      
ENSG00000138443 E040 15.9515879 0.0011411863 1.528873e-02 1.065259e-01 2 203402576 203402705 130 + 1.315 1.138 -0.628
ENSG00000138443 E041 9.7343768 0.0020817327 2.573632e-02 1.481865e-01 2 203402706 203402734 29 + 1.128 0.925 -0.746
ENSG00000138443 E042 0.0000000       2 203403317 203403361 45 +      
ENSG00000138443 E043 8.1261106 0.0018028121 4.086611e-01 6.909050e-01 2 203411285 203411371 87 + 0.916 0.991 0.279
ENSG00000138443 E044 18.6468409 0.0068627780 2.246108e-02 1.362673e-01 2 203416908 203417081 174 + 1.376 1.205 -0.599
ENSG00000138443 E045 11.8906596 0.0273343367 8.455036e-01 9.450825e-01 2 203427177 203427269 93 + 1.119 1.099 -0.072
ENSG00000138443 E046 196.0025979 0.0001572837 1.402065e-11 1.559154e-09 2 203427270 203436670 9401 + 2.237 2.334 0.324
ENSG00000138443 E047 3.3017366 0.0046246214 6.545576e-01 8.550239e-01 2 203436671 203447728 11058 + 0.665 0.603 -0.268

Help

Please Click HERE to learn more details about the results from DEXseq.