ENSG00000138600

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261854 ENSG00000138600 No_inf pgKDN_inf SPPL2A protein_coding protein_coding 130.0047 61.84097 158.7338 3.215509 3.293458 1.359832 19.25709 15.2255611 23.39355 0.4839222 0.4521319 0.6192849 0.17035833 0.249775 0.147625 -0.102150 0.1026116189 0.0009572946 FALSE TRUE
ENST00000558414 ENSG00000138600 No_inf pgKDN_inf SPPL2A protein_coding protein_coding 130.0047 61.84097 158.7338 3.215509 3.293458 1.359832 30.46581 9.0332173 33.25111 3.2555621 5.7928163 1.8789285 0.21080833 0.139150 0.207975 0.068825 0.8032725661 0.0009572946 FALSE FALSE
ENST00000558934 ENSG00000138600 No_inf pgKDN_inf SPPL2A protein_coding protein_coding 130.0047 61.84097 158.7338 3.215509 3.293458 1.359832 60.05577 31.5557792 76.17903 1.3998547 3.6594077 1.2712220 0.47368333 0.511475 0.480175 -0.031300 0.8415597665 0.0009572946 FALSE TRUE
ENST00000698135 ENSG00000138600 No_inf pgKDN_inf SPPL2A protein_coding protein_coding 130.0047 61.84097 158.7338 3.215509 3.293458 1.359832 13.05773 0.6959604 19.46969 0.5658743 1.9737932 4.7862393 0.08231667 0.010500 0.123300 0.112800 0.0009572946 0.0009572946 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138600 E001 446.5864447 0.0008214606 1.258412e-15 2.262373e-13 15 50702266 50706766 4501 - 2.582 2.712 0.435
ENSG00000138600 E002 44.0117889 0.0009051736 4.922053e-02 2.187278e-01 15 50706767 50707447 681 - 1.598 1.698 0.340
ENSG00000138600 E003 21.1674945 0.0039723052 9.971906e-02 3.299538e-01 15 50707448 50707600 153 - 1.282 1.402 0.419
ENSG00000138600 E004 138.7789401 0.0001699109 3.072004e-01 6.004542e-01 15 50707601 50707874 274 - 2.135 2.116 -0.063
ENSG00000138600 E005 0.0000000       15 50718178 50718183 6 -      
ENSG00000138600 E006 0.3711203 0.0166434062 2.708944e-01   15 50718184 50718604 421 - 0.071 0.224 1.922
ENSG00000138600 E007 2.4964327 0.0055566228 3.107655e-04 5.968955e-03 15 50718605 50719939 1335 - 0.276 0.782 2.507
ENSG00000138600 E008 113.7795381 0.0064682398 6.425596e-01 8.484089e-01 15 50719940 50720100 161 - 2.032 2.061 0.098
ENSG00000138600 E009 54.2040046 0.0090464754 1.933081e-01 4.731080e-01 15 50722124 50722172 49 - 1.749 1.680 -0.235
ENSG00000138600 E010 45.2730068 0.0060959367 1.719412e-01 4.446218e-01 15 50722173 50722201 29 - 1.673 1.603 -0.237
ENSG00000138600 E011 56.8476189 0.0002884873 4.162808e-01 6.961548e-01 15 50725221 50725268 48 - 1.755 1.729 -0.087
ENSG00000138600 E012 56.3805341 0.0027135981 5.303740e-01 7.814772e-01 15 50725269 50725323 55 - 1.728 1.765 0.127
ENSG00000138600 E013 0.4986623 0.0316941647 1.105545e-01   15 50725324 50725519 196 - 0.071 0.303 2.507
ENSG00000138600 E014 0.2536433 0.0159923868 9.263488e-02   15 50725916 50726072 157 - 0.000 0.224 11.862
ENSG00000138600 E015 19.1002860 0.0008237245 9.760745e-02 3.256440e-01 15 50726073 50726126 54 - 1.240 1.360 0.421
ENSG00000138600 E016 6.9178427 0.0020152834 5.729900e-01 8.086848e-01 15 50726127 50726252 126 - 0.859 0.925 0.252
ENSG00000138600 E017 4.9521680 0.0034434810 6.628909e-01 8.594862e-01 15 50726253 50726320 68 - 0.777 0.731 -0.185
ENSG00000138600 E018 52.8522269 0.0003112646 5.121471e-01 7.691995e-01 15 50726321 50726377 57 - 1.701 1.737 0.121
ENSG00000138600 E019 1.6143793 0.0084065762 1.312433e-02 9.596631e-02 15 50726378 50728416 2039 - 0.233 0.606 2.092
ENSG00000138600 E020 60.7296332 0.0019155693 6.303130e-01 8.414470e-01 15 50730965 50731039 75 - 1.778 1.765 -0.044
ENSG00000138600 E021 74.2704325 0.0003573828 7.308826e-02 2.746821e-01 15 50732603 50732684 82 - 1.880 1.822 -0.196
ENSG00000138600 E022 1.8246569 0.0076284470 6.893401e-01 8.722389e-01 15 50732685 50736100 3416 - 0.415 0.480 0.337
ENSG00000138600 E023 66.5717127 0.0004104101 2.547744e-05 7.583334e-04 15 50736101 50736202 102 - 1.864 1.704 -0.544
ENSG00000138600 E024 71.1560675 0.0080361858 2.838425e-02 1.576597e-01 15 50736644 50736740 97 - 1.878 1.768 -0.371
ENSG00000138600 E025 88.6051666 0.0001906344 1.224053e-02 9.156460e-02 15 50739680 50739828 149 - 1.961 1.885 -0.256
ENSG00000138600 E026 29.6650583 0.0005400621 4.268794e-02 2.013448e-01 15 50747495 50747503 9 - 1.507 1.397 -0.380
ENSG00000138600 E027 63.2415045 0.0007251060 2.980059e-04 5.773223e-03 15 50747504 50747628 125 - 1.837 1.695 -0.482
ENSG00000138600 E028 0.1170040 0.0116786747 1.000000e+00   15 50747997 50748112 116 - 0.071 0.000 -10.015
ENSG00000138600 E029 53.1713447 0.0002775721 5.672000e-03 5.421767e-02 15 50748113 50748202 90 - 1.755 1.641 -0.384
ENSG00000138600 E030 52.6712823 0.0002889491 2.287081e-03 2.825921e-02 15 50748688 50748870 183 - 1.755 1.628 -0.430
ENSG00000138600 E031 2.5091063 0.0116267990 1.167440e-01 3.604788e-01 15 50749636 50749746 111 - 0.605 0.371 -1.165
ENSG00000138600 E032 0.1272623 0.0123606974 2.776834e-01   15 50764507 50764561 55 - 0.000 0.126 10.936
ENSG00000138600 E033 21.0654538 0.0008805384 1.475693e-02 1.038763e-01 15 50765468 50765948 481 - 1.379 1.217 -0.566

Help

Please Click HERE to learn more details about the results from DEXseq.