ENSG00000138660

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274000 ENSG00000138660 No_inf pgKDN_inf AP1AR protein_coding protein_coding 8.387682 5.029291 9.055348 1.042859 0.4139956 0.8471415 2.9163557 0.7884647 5.474995 0.7884647 0.1910614 2.780190 0.3747083 0.250000 0.606200 0.356200 0.18576149 0.01473682 FALSE TRUE
ENST00000506522 ENSG00000138660 No_inf pgKDN_inf AP1AR protein_coding retained_intron 8.387682 5.029291 9.055348 1.042859 0.4139956 0.8471415 0.1036199 0.3108597 0.000000 0.3108597 0.0000000 -5.003871 0.0194750 0.058425 0.000000 -0.058425 0.79570539 0.01473682   FALSE
ENST00000510527 ENSG00000138660 No_inf pgKDN_inf AP1AR protein_coding retained_intron 8.387682 5.029291 9.055348 1.042859 0.4139956 0.8471415 2.6433281 1.1302706 3.224228 0.4555195 0.3676495 1.504045 0.2923417 0.196825 0.353025 0.156200 0.65383069 0.01473682 FALSE TRUE
ENST00000512741 ENSG00000138660 No_inf pgKDN_inf AP1AR protein_coding protein_coding 8.387682 5.029291 9.055348 1.042859 0.4139956 0.8471415 1.1516608 0.7560963 0.000000 0.7560963 0.0000000 -6.259454 0.1041750 0.096375 0.000000 -0.096375 0.78589503 0.01473682   FALSE
MSTRG.22181.1 ENSG00000138660 No_inf pgKDN_inf AP1AR protein_coding   8.387682 5.029291 9.055348 1.042859 0.4139956 0.8471415 1.4074133 2.0435999 0.000000 0.6895860 0.0000000 -7.682011 0.1928333 0.398375 0.000000 -0.398375 0.01473682 0.01473682 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138660 E001 0.1186381 0.011822577 1.000000000   4 112231614 112231648 35 + 0.068 0.000 -7.961
ENSG00000138660 E002 0.3631878 0.016937955 1.000000000   4 112231740 112231786 47 + 0.127 0.132 0.065
ENSG00000138660 E003 0.4903241 0.016273520 0.501174772   4 112231787 112231824 38 + 0.127 0.233 1.065
ENSG00000138660 E004 0.9612275 0.012590436 0.599812943 0.82458531 4 112231825 112231832 8 + 0.304 0.233 -0.520
ENSG00000138660 E005 1.6802038 0.032232836 0.332827249 0.62491575 4 112231833 112231888 56 + 0.457 0.314 -0.809
ENSG00000138660 E006 1.9090469 0.031208697 0.061142520 0.24835523 4 112231889 112231923 35 + 0.528 0.233 -1.742
ENSG00000138660 E007 6.9325309 0.002191375 0.004949628 0.04925336 4 112231924 112232174 251 + 0.960 0.657 -1.198
ENSG00000138660 E008 3.7254086 0.010021697 0.360333034 0.64999505 4 112253208 112253256 49 + 0.689 0.583 -0.458
ENSG00000138660 E009 0.1268540 0.012394504 0.258241791   4 112253257 112253311 55 + 0.000 0.132 10.470
ENSG00000138660 E010 2.8021267 0.005649390 0.327993191 0.62048351 4 112254747 112254773 27 + 0.505 0.657 0.687
ENSG00000138660 E011 0.0000000       4 112254774 112254894 121 +      
ENSG00000138660 E012 3.6375830 0.025087463 0.732979607 0.89381451 4 112257772 112257797 26 + 0.625 0.690 0.277
ENSG00000138660 E013 7.1137593 0.058550866 0.797825941 0.92380567 4 112260766 112260862 97 + 0.899 0.868 -0.121
ENSG00000138660 E014 7.9321287 0.002562079 0.165355643 0.43501738 4 112262988 112263086 99 + 0.968 0.846 -0.462
ENSG00000138660 E015 6.1181698 0.002650394 0.115402459 0.35814007 4 112265009 112265051 43 + 0.881 0.720 -0.635
ENSG00000138660 E016 4.5820375 0.003701742 0.540665363 0.78863040 4 112265052 112265067 16 + 0.746 0.690 -0.230
ENSG00000138660 E017 1.4959022 0.022776905 0.004320473 0.04475997 4 112265068 112265319 252 + 0.178 0.622 2.650
ENSG00000138660 E018 7.8036708 0.001897860 0.061237574 0.24851427 4 112265734 112265807 74 + 0.976 0.800 -0.672
ENSG00000138660 E019 9.8746316 0.006384046 0.197747324 0.47916723 4 112266588 112266716 129 + 1.047 0.944 -0.382
ENSG00000138660 E020 0.2457744 0.016156766 0.595291754   4 112266717 112266830 114 + 0.068 0.132 1.065
ENSG00000138660 E021 100.9792144 0.006705707 0.001153076 0.01670875 4 112268144 112273110 4967 + 1.948 2.050 0.343

Help

Please Click HERE to learn more details about the results from DEXseq.