ENSG00000138698

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000339360 ENSG00000138698 No_inf pgKDN_inf RAP1GDS1 protein_coding protein_coding 47.65066 38.45853 63.7048 0.5135476 1.463406 0.7279497 6.206299 6.364557 6.715744 4.266212 4.282798 0.07736882 0.13740833 0.167925 0.107425 -0.060500 1.00000000 0.01642708 FALSE TRUE
ENST00000380158 ENSG00000138698 No_inf pgKDN_inf RAP1GDS1 protein_coding protein_coding 47.65066 38.45853 63.7048 0.5135476 1.463406 0.7279497 4.827952 2.393552 6.556659 1.724621 2.534845 1.44999142 0.09965000 0.061925 0.101250 0.039325 0.80878562 0.01642708 FALSE TRUE
ENST00000408900 ENSG00000138698 No_inf pgKDN_inf RAP1GDS1 protein_coding protein_coding 47.65066 38.45853 63.7048 0.5135476 1.463406 0.7279497 1.116117 3.348352 0.000000 1.498282 0.000000 -8.39160967 0.02935833 0.088075 0.000000 -0.088075 0.01642708 0.01642708 FALSE TRUE
ENST00000408927 ENSG00000138698 No_inf pgKDN_inf RAP1GDS1 protein_coding protein_coding 47.65066 38.45853 63.7048 0.5135476 1.463406 0.7279497 26.394477 20.746355 33.184982 4.558326 3.455314 0.67741203 0.55897500 0.536775 0.521850 -0.014925 0.99403343 0.01642708 FALSE TRUE
ENST00000509501 ENSG00000138698 No_inf pgKDN_inf RAP1GDS1 protein_coding protein_coding 47.65066 38.45853 63.7048 0.5135476 1.463406 0.7279497 2.616444 0.000000 7.849332 0.000000 3.021301 9.61826292 0.04052500 0.000000 0.121575 0.121575 0.02085322 0.01642708 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138698 E001 1.0952613 0.0586316434 9.214550e-01 9.754795e-01 4 98261384 98261395 12 + 0.312 0.330 0.112
ENSG00000138698 E002 2.1821509 0.0288416741 7.622439e-01 9.072585e-01 4 98261396 98261416 21 + 0.521 0.476 -0.218
ENSG00000138698 E003 2.5460642 0.0063907160 6.728709e-01 8.644716e-01 4 98261417 98261422 6 + 0.573 0.515 -0.267
ENSG00000138698 E004 2.5460642 0.0063907160 6.728709e-01 8.644716e-01 4 98261423 98261430 8 + 0.573 0.515 -0.267
ENSG00000138698 E005 2.5460642 0.0063907160 6.728709e-01 8.644716e-01 4 98261431 98261433 3 + 0.573 0.515 -0.267
ENSG00000138698 E006 3.4011179 0.0041776299 7.175692e-01 8.864062e-01 4 98261434 98261450 17 + 0.661 0.616 -0.194
ENSG00000138698 E007 3.4011179 0.0041776299 7.175692e-01 8.864062e-01 4 98261451 98261456 6 + 0.661 0.616 -0.194
ENSG00000138698 E008 3.2834873 0.0044133432 8.388543e-01 9.421455e-01 4 98261457 98261459 3 + 0.640 0.616 -0.107
ENSG00000138698 E009 2.9209912 0.0049793241 9.198912e-01 9.750314e-01 4 98261460 98261460 1 + 0.596 0.585 -0.052
ENSG00000138698 E010 3.6575590 0.0038918152 9.443889e-01 9.845722e-01 4 98261461 98261468 8 + 0.661 0.672 0.047
ENSG00000138698 E011 5.0994825 0.0027158314 5.491637e-01 7.938940e-01 4 98261469 98261478 10 + 0.811 0.744 -0.267
ENSG00000138698 E012 3.8976964 0.0096710850 8.194056e-01 9.342908e-01 4 98261479 98261485 7 + 0.699 0.672 -0.114
ENSG00000138698 E013 3.6517309 0.0042652730 7.679705e-01 9.102334e-01 4 98261486 98261502 17 + 0.680 0.645 -0.151
ENSG00000138698 E014 3.2878176 0.0049876934 8.395437e-01 9.424291e-01 4 98261503 98261517 15 + 0.640 0.616 -0.107
ENSG00000138698 E015 2.6787294 0.0052810234 8.671686e-01 9.542307e-01 4 98261518 98261569 52 + 0.573 0.551 -0.097
ENSG00000138698 E016 0.0000000       4 98293405 98293407 3 +      
ENSG00000138698 E017 12.1213048 0.0100811064 2.173679e-01 5.037703e-01 4 98293408 98293515 108 + 1.161 1.051 -0.396
ENSG00000138698 E018 0.8526268 0.1576232177 9.640509e-01 9.924265e-01 4 98296918 98296990 73 + 0.265 0.268 0.019
ENSG00000138698 E019 34.1465657 0.0004520850 3.344906e-01 6.263164e-01 4 98343139 98343261 123 + 1.563 1.517 -0.160
ENSG00000138698 E020 0.6071071 0.0147442325 9.039799e-01 9.690774e-01 4 98343262 98343319 58 + 0.213 0.196 -0.151
ENSG00000138698 E021 20.1726590 0.0050915923 5.773091e-01 8.111200e-01 4 98352476 98352512 37 + 1.339 1.302 -0.129
ENSG00000138698 E022 31.3503172 0.0010389402 7.070425e-03 6.348199e-02 4 98352513 98352601 89 + 1.566 1.420 -0.500
ENSG00000138698 E023 29.2209120 0.0005100998 5.093392e-02 2.233255e-01 4 98379017 98379101 85 + 1.521 1.416 -0.364
ENSG00000138698 E024 28.4151837 0.0005327574 2.379744e-01 5.269320e-01 4 98379102 98379158 57 + 1.493 1.430 -0.218
ENSG00000138698 E025 17.2756624 0.0008173911 7.830881e-01 9.165837e-01 4 98379159 98379163 5 + 1.267 1.250 -0.059
ENSG00000138698 E026 0.6343927 0.0152921867 8.515418e-03 7.206505e-02 4 98379164 98379490 327 + 0.000 0.384 12.649
ENSG00000138698 E027 0.4906372 0.1065754905 7.752350e-01   4 98387436 98387503 68 + 0.153 0.196 0.433
ENSG00000138698 E028 0.3719991 0.0165065001 4.175697e-01   4 98387504 98387507 4 + 0.083 0.196 1.434
ENSG00000138698 E029 44.0531147 0.0056703367 1.518851e-01 4.155516e-01 4 98391952 98392080 129 + 1.683 1.608 -0.254
ENSG00000138698 E030 0.1176306 0.0117298654 7.214146e-01   4 98392081 98392252 172 + 0.083 0.000 -10.763
ENSG00000138698 E031 0.9986792 0.0121274721 6.659039e-02 2.599512e-01 4 98395941 98396909 969 + 0.153 0.432 2.019
ENSG00000138698 E032 41.6217127 0.0042345108 9.268283e-02 3.162055e-01 4 98404477 98404602 126 + 1.663 1.576 -0.296
ENSG00000138698 E033 49.4868988 0.0038437666 9.586259e-01 9.901969e-01 4 98416745 98416888 144 + 1.698 1.703 0.019
ENSG00000138698 E034 51.3034599 0.0011991501 2.840599e-01 5.778046e-01 4 98417367 98417498 132 + 1.735 1.691 -0.148
ENSG00000138698 E035 53.6569174 0.0033871873 5.927249e-01 8.204082e-01 4 98418657 98418791 135 + 1.745 1.722 -0.075
ENSG00000138698 E036 58.5569471 0.0002779108 1.398631e-01 3.978154e-01 4 98420019 98420144 126 + 1.796 1.741 -0.186
ENSG00000138698 E037 19.1179089 0.0256706713 9.930506e-01 1.000000e+00 4 98421255 98421257 3 + 1.300 1.302 0.008
ENSG00000138698 E038 65.5128875 0.0004056165 3.048236e-01 5.980835e-01 4 98421258 98421394 137 + 1.802 1.842 0.137
ENSG00000138698 E039 65.0116382 0.0002614137 1.700595e-01 4.421791e-01 4 98433936 98434062 127 + 1.838 1.790 -0.162
ENSG00000138698 E040 68.6069342 0.0002287456 8.210577e-01 9.350145e-01 4 98436940 98437068 129 + 1.835 1.846 0.037
ENSG00000138698 E041 384.1175668 0.0004584945 4.353046e-08 2.739524e-06 4 98441990 98443858 1869 + 2.546 2.625 0.264

Help

Please Click HERE to learn more details about the results from DEXseq.