ENSG00000138750

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264883 ENSG00000138750 No_inf pgKDN_inf NUP54 protein_coding protein_coding 18.49922 17.72088 19.53797 1.928121 0.4682103 0.1407546 10.1065736 7.594125 14.5493261 2.5979013 1.1843972 0.9370894 0.55820000 0.479900 0.745775 0.265875 0.69631489 0.03523514 FALSE TRUE
ENST00000508604 ENSG00000138750 No_inf pgKDN_inf NUP54 protein_coding retained_intron 18.49922 17.72088 19.53797 1.928121 0.4682103 0.1407546 0.5878064 1.219022 0.4112694 0.4718170 0.2877599 -1.5446962 0.03435833 0.074475 0.020525 -0.053950 0.65649558 0.03523514 TRUE FALSE
ENST00000514987 ENSG00000138750 No_inf pgKDN_inf NUP54 protein_coding protein_coding 18.49922 17.72088 19.53797 1.928121 0.4682103 0.1407546 2.5197286 2.049082 0.0000000 0.7274184 0.0000000 -7.6858574 0.13757500 0.115150 0.000000 -0.115150 0.03523514 0.03523514 FALSE TRUE
ENST00000515460 ENSG00000138750 No_inf pgKDN_inf NUP54 protein_coding protein_coding 18.49922 17.72088 19.53797 1.928121 0.4682103 0.1407546 0.6112799 1.649107 0.1847326 1.5103412 0.1847326 -3.0908410 0.02734167 0.072675 0.009350 -0.063325 0.82287685 0.03523514 FALSE TRUE
MSTRG.21919.12 ENSG00000138750 No_inf pgKDN_inf NUP54 protein_coding   18.49922 17.72088 19.53797 1.928121 0.4682103 0.1407546 0.6975900 0.000000 0.9911681 0.0000000 0.9911681 6.6455405 0.03684167 0.000000 0.050175 0.050175 0.84904498 0.03523514 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138750 E001 0.1272623 0.0123942537 0.53141396   4 76107562 76112622 5061 - 0.000 0.096 10.905
ENSG00000138750 E002 0.1272623 0.0123942537 0.53141396   4 76112792 76114658 1867 - 0.000 0.096 12.385
ENSG00000138750 E003 0.1265070 0.0123345462 0.53142712   4 76114659 76114663 5 - 0.000 0.096 12.385
ENSG00000138750 E004 0.3714000 0.0165212804 0.57557341   4 76114664 76114678 15 - 0.095 0.174 1.018
ENSG00000138750 E005 0.4901032 0.0161557713 0.98991075   4 76114679 76114691 13 - 0.172 0.174 0.018
ENSG00000138750 E006 0.4901032 0.0161557713 0.98991075   4 76114692 76114697 6 - 0.172 0.174 0.018
ENSG00000138750 E007 0.6169571 0.0147693125 0.64664592 0.85038715 4 76114698 76114707 10 - 0.172 0.240 0.603
ENSG00000138750 E008 3.3011660 0.0044174208 0.87351376 0.95691722 4 76114708 76114743 36 - 0.644 0.623 -0.089
ENSG00000138750 E009 9.8765832 0.0015879887 0.34455813 0.63574288 4 76114744 76114867 124 - 1.077 0.994 -0.304
ENSG00000138750 E010 6.5989630 0.0030686910 0.82259076 0.93562321 4 76114868 76114897 30 - 0.893 0.869 -0.089
ENSG00000138750 E011 25.0093544 0.0006153494 0.60763091 0.82915330 4 76114898 76115086 189 - 1.399 1.429 0.103
ENSG00000138750 E012 10.8294320 0.0211834272 0.26696069 0.56023978 4 76115087 76115103 17 - 1.010 1.124 0.414
ENSG00000138750 E013 31.0641146 0.0030098905 0.69403184 0.87492222 4 76115104 76115300 197 - 1.517 1.495 -0.073
ENSG00000138750 E014 13.6864302 0.0010014096 0.61112757 0.83087050 4 76115301 76115343 43 - 1.186 1.148 -0.137
ENSG00000138750 E015 20.0216159 0.0006860611 0.30018187 0.59306076 4 76115344 76115437 94 - 1.355 1.289 -0.229
ENSG00000138750 E016 14.8374525 0.0009379713 0.73453825 0.89466330 4 76115438 76115494 57 - 1.186 1.211 0.089
ENSG00000138750 E017 0.7443758 0.0141298485 0.40577852 0.68844231 4 76115495 76117663 2169 - 0.172 0.298 1.018
ENSG00000138750 E018 17.4428990 0.0008365611 0.35857476 0.64814570 4 76117664 76117742 79 - 1.232 1.295 0.221
ENSG00000138750 E019 9.3369080 0.0094877743 0.50306258 0.76265308 4 76117743 76117774 32 - 0.978 1.045 0.246
ENSG00000138750 E020 1.1238964 0.0110461999 0.08633850 0.30441905 4 76117775 76118074 300 - 0.172 0.435 1.825
ENSG00000138750 E021 19.9207155 0.0357331876 0.50621456 0.76498111 4 76118075 76118194 120 - 1.351 1.289 -0.214
ENSG00000138750 E022 1.1159389 0.0117224699 0.31037904 0.60350361 4 76118195 76118437 243 - 0.238 0.394 1.018
ENSG00000138750 E023 0.2455571 0.0162347511 0.99333414   4 76124580 76124648 69 - 0.095 0.096 0.018
ENSG00000138750 E024 17.2986579 0.0008379139 0.07180322 0.27174477 4 76124649 76124756 108 - 1.321 1.198 -0.433
ENSG00000138750 E025 13.5976164 0.0010496837 0.87464134 0.95712588 4 76130656 76130718 63 - 1.158 1.170 0.044
ENSG00000138750 E026 9.1241237 0.0022434254 0.09444220 0.31981200 4 76130719 76130749 31 - 0.919 1.073 0.570
ENSG00000138750 E027 0.6086152 0.0147884578 0.66576920 0.86099407 4 76130750 76130792 43 - 0.238 0.174 -0.567
ENSG00000138750 E028 3.8407715 0.1486851910 0.36430294 0.65307169 4 76130793 76131229 437 - 0.566 0.773 0.879
ENSG00000138750 E029 10.6404125 0.0305136518 0.98237617 0.99866264 4 76131230 76131284 55 - 1.068 1.064 -0.015
ENSG00000138750 E030 7.3088235 0.0019491059 0.01137586 0.08756184 4 76131285 76132522 1238 - 0.768 1.025 0.981
ENSG00000138750 E031 21.4485624 0.0006179926 0.07717326 0.28415227 4 76132523 76132714 192 - 1.404 1.295 -0.378
ENSG00000138750 E032 6.7203750 0.0020858901 0.71945525 0.88684392 4 76132715 76132719 5 - 0.906 0.869 -0.140
ENSG00000138750 E033 17.3013244 0.0008711462 0.14493198 0.40528654 4 76134175 76134362 188 - 1.311 1.211 -0.350
ENSG00000138750 E034 4.0162240 0.0530971397 0.52054523 0.77482714 4 76136186 76136187 2 - 0.750 0.648 -0.423
ENSG00000138750 E035 8.2614094 0.0414250731 0.30626157 0.59938716 4 76136188 76136281 94 - 1.030 0.897 -0.496
ENSG00000138750 E036 5.9564259 0.0024837413 0.21428968 0.49956774 4 76136282 76136320 39 - 0.906 0.773 -0.518
ENSG00000138750 E037 8.7174025 0.0024900525 0.52393153 0.77707961 4 76136321 76136412 92 - 0.956 1.015 0.221
ENSG00000138750 E038 6.1769754 0.0035409209 0.08421281 0.29967045 4 76144149 76144183 35 - 0.750 0.936 0.724
ENSG00000138750 E039 4.8106312 0.0031783913 0.24933463 0.54019498 4 76144184 76144196 13 - 0.690 0.824 0.541
ENSG00000138750 E040 8.2269507 0.0017418899 0.51115631 0.76840138 4 76144197 76144292 96 - 0.932 0.994 0.233
ENSG00000138750 E041 6.6384040 0.0343224717 0.48631686 0.75002382 4 76144390 76144473 84 - 0.835 0.924 0.340
ENSG00000138750 E042 0.9771549 0.0178348814 0.98525723 0.99899506 4 76144474 76145192 719 - 0.295 0.298 0.018
ENSG00000138750 E043 0.4977836 0.0167057195 0.31389209   4 76145193 76145554 362 - 0.095 0.240 1.603
ENSG00000138750 E044 0.2441403 0.0162297823 0.99297942   4 76145555 76145577 23 - 0.095 0.096 0.018
ENSG00000138750 E045 0.8805177 0.0154615914 0.04888186 0.21782302 4 76145578 76145691 114 - 0.095 0.394 2.603
ENSG00000138750 E046 0.2536433 0.0160554934 0.23809044   4 76145692 76145982 291 - 0.000 0.174 13.370
ENSG00000138750 E047 0.1272623 0.0123942537 0.53141396   4 76145983 76146129 147 - 0.000 0.096 12.385
ENSG00000138750 E048 0.2459655 0.0161705688 0.99252260   4 76146130 76146149 20 - 0.095 0.096 0.018
ENSG00000138750 E049 0.4910456 0.0559860061 0.98704216   4 76147479 76147640 162 - 0.172 0.174 0.017
ENSG00000138750 E050 0.2373413 0.0157141414 0.24639783   4 76147756 76147821 66 - 0.172 0.000 -13.494
ENSG00000138750 E051 0.2372762 0.2578488857 0.30297726   4 76148090 76148307 218 - 0.172 0.000 -13.488
ENSG00000138750 E052 4.5145563 0.0242157589 0.46976072 0.73784363 4 76148308 76148485 178 - 0.786 0.694 -0.375

Help

Please Click HERE to learn more details about the results from DEXseq.