ENSG00000138756

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000502613 ENSG00000138756 No_inf pgKDN_inf BMP2K protein_coding protein_coding 28.77348 40.94169 26.26229 0.707748 0.4888209 -0.6403811 12.454436 13.774926 12.947756 3.2694155 0.19974571 -0.0892756 0.4649667 0.339600 0.493900 0.15430 0.5025505 0.0315196 FALSE TRUE
ENST00000507670 ENSG00000138756 No_inf pgKDN_inf BMP2K protein_coding retained_intron 28.77348 40.94169 26.26229 0.707748 0.4888209 -0.6403811 3.677516 6.690903 2.884382 0.5587472 0.20808467 -1.2111003 0.1160583 0.163525 0.109625 -0.05390 0.6802934 0.0315196 FALSE TRUE
MSTRG.21962.3 ENSG00000138756 No_inf pgKDN_inf BMP2K protein_coding   28.77348 40.94169 26.26229 0.707748 0.4888209 -0.6403811 6.790003 8.961302 8.102265 3.3875490 0.62391480 -0.1452127 0.2311417 0.216125 0.307625 0.09150 0.8181276 0.0315196 FALSE TRUE
MSTRG.21962.7 ENSG00000138756 No_inf pgKDN_inf BMP2K protein_coding   28.77348 40.94169 26.26229 0.707748 0.4888209 -0.6403811 4.437438 9.172872 2.082492 0.9177309 0.09158879 -2.1337237 0.1376417 0.223400 0.079550 -0.14385 0.0315196 0.0315196 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138756 E001 0.2542726 0.2281715255 5.096417e-01   4 78776342 78776349 8 + 0.000 0.142 10.171
ENSG00000138756 E002 0.5079160 0.1758395376 1.681649e-01 4.392370e-01 4 78776350 78776377 28 + 0.000 0.248 11.173
ENSG00000138756 E003 7.9387672 0.0018312722 1.134431e-02 8.739273e-02 4 78776378 78776721 344 + 1.074 0.832 -0.909
ENSG00000138756 E004 12.6714285 0.0377941712 3.613226e-01 6.508101e-01 4 78826037 78826155 119 + 1.175 1.086 -0.321
ENSG00000138756 E005 13.1733602 0.0039412928 3.338936e-01 6.258068e-01 4 78833582 78833687 106 + 1.184 1.106 -0.280
ENSG00000138756 E006 22.9022818 0.0215658673 3.418723e-01 6.333221e-01 4 78842385 78842527 143 + 1.413 1.331 -0.282
ENSG00000138756 E007 23.8825458 0.0006110409 1.912898e-01 4.707316e-01 4 78844928 78845049 122 + 1.428 1.350 -0.268
ENSG00000138756 E008 17.4512469 0.0008803000 9.603031e-02 3.227581e-01 4 78847188 78847269 82 + 1.320 1.205 -0.402
ENSG00000138756 E009 0.2444846 0.0161003286 7.104892e-01   4 78850892 78850923 32 + 0.117 0.077 -0.687
ENSG00000138756 E010 21.2007348 0.0032984443 5.298257e-01 7.811814e-01 4 78850924 78851056 133 + 1.357 1.315 -0.144
ENSG00000138756 E011 0.0000000       4 78859167 78859583 417 +      
ENSG00000138756 E012 20.7083766 0.0024865736 1.551101e-01 4.208314e-01 4 78859584 78859687 104 + 1.257 1.354 0.339
ENSG00000138756 E013 0.0000000       4 78860036 78860079 44 +      
ENSG00000138756 E014 17.8779125 0.0054710868 5.738399e-01 8.090234e-01 4 78861389 78861468 80 + 1.286 1.245 -0.143
ENSG00000138756 E015 0.0000000       4 78861469 78861469 1 +      
ENSG00000138756 E016 21.6917232 0.0007272302 3.794041e-01 6.662160e-01 4 78865557 78865720 164 + 1.374 1.320 -0.190
ENSG00000138756 E017 1.5024127 0.0190083860 1.092876e-01 3.470102e-01 4 78865721 78865773 53 + 0.210 0.467 1.635
ENSG00000138756 E018 16.0714069 0.0010586981 1.391702e-08 9.623085e-07 4 78869962 78870782 821 + 0.858 1.339 1.746
ENSG00000138756 E019 24.1299194 0.0042357834 6.077445e-01 8.291533e-01 4 78870783 78871060 278 + 1.363 1.397 0.117
ENSG00000138756 E020 11.8934528 0.0185133674 5.035397e-01 7.630270e-01 4 78871850 78871948 99 + 1.051 1.119 0.246
ENSG00000138756 E021 0.2459655 0.0162137396 7.109639e-01   4 78872328 78872613 286 + 0.117 0.077 -0.687
ENSG00000138756 E022 23.5648657 0.0007736528 6.684273e-01 8.619436e-01 4 78872614 78872760 147 + 1.391 1.365 -0.089
ENSG00000138756 E023 12.3048902 0.0059756292 3.628306e-01 6.519203e-01 4 78872761 78872798 38 + 1.157 1.079 -0.280
ENSG00000138756 E024 27.5174125 0.0045395261 7.360505e-01 8.952316e-01 4 78878734 78878891 158 + 1.452 1.432 -0.070
ENSG00000138756 E025 33.1179653 0.0018759711 1.162520e-04 2.689805e-03 4 78878892 78879969 1078 + 1.368 1.585 0.743
ENSG00000138756 E026 0.0000000       4 78887174 78887284 111 +      
ENSG00000138756 E027 16.4717996 0.0008182811 1.218263e-01 3.693951e-01 4 78910610 78916365 5756 + 1.293 1.184 -0.384

Help

Please Click HERE to learn more details about the results from DEXseq.