ENSG00000138758

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264893 ENSG00000138758 No_inf pgKDN_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 35.08709 0.8705059 1.959022 0.7032839 20.6431340 13.697012 25.867977 0.4160818 0.7961651 0.9168108 0.70915000 0.637100 0.741625 0.104525 4.667134e-01 7.847263e-05 FALSE  
ENST00000502401 ENSG00000138758 No_inf pgKDN_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 35.08709 0.8705059 1.959022 0.7032839 1.5305682 1.558137 2.411173 0.5941755 1.0553922 0.6266549 0.05321667 0.069250 0.067250 -0.002000 1.000000e+00 7.847263e-05    
ENST00000502584 ENSG00000138758 No_inf pgKDN_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 35.08709 0.8705059 1.959022 0.7032839 2.7453141 3.307051 2.900441 0.2224248 0.4454670 -0.1886635 0.10129167 0.154425 0.082350 -0.072075 4.654621e-01 7.847263e-05 FALSE  
ENST00000512575 ENSG00000138758 No_inf pgKDN_inf SEPTIN11 protein_coding protein_coding_CDS_not_defined 28.99101 21.54567 35.08709 0.8705059 1.959022 0.7032839 2.0005220 0.000000 2.317928 0.0000000 1.6001412 7.8629026 0.05765833 0.000000 0.064425 0.064425 5.569296e-01 7.847263e-05    
ENST00000513373 ENSG00000138758 No_inf pgKDN_inf SEPTIN11 protein_coding protein_coding_CDS_not_defined 28.99101 21.54567 35.08709 0.8705059 1.959022 0.7032839 0.5828878 1.748663 0.000000 0.3656964 0.0000000 -7.4583356 0.02692500 0.080775 0.000000 -0.080775 7.847263e-05 7.847263e-05    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000138758 E001 0.2356421 0.0155872338 4.563944e-01   4 76949751 76949751 1 + 0.140 0.000 -10.779
ENSG00000138758 E002 0.8262561 0.0128750703 2.287834e-02 1.379453e-01 4 76949752 76949765 14 + 0.368 0.000 -14.768
ENSG00000138758 E003 1.6689417 0.0079854593 4.998737e-02 2.207164e-01 4 76949766 76949808 43 + 0.516 0.212 -1.856
ENSG00000138758 E004 3.1198656 0.0045021905 1.033092e-01 3.360133e-01 4 76949809 76949835 27 + 0.681 0.461 -1.008
ENSG00000138758 E005 3.1198006 0.0046838068 1.036227e-01 3.364655e-01 4 76949836 76949836 1 + 0.681 0.461 -1.008
ENSG00000138758 E006 3.6210435 0.0040336121 3.527984e-01 6.428241e-01 4 76949837 76949861 25 + 0.698 0.584 -0.494
ENSG00000138758 E007 5.7093179 0.0162355005 9.926739e-01 1.000000e+00 4 76949862 76949930 69 + 0.814 0.824 0.041
ENSG00000138758 E008 0.1271363 0.0123582251 3.257661e-01   4 76972390 76972590 201 + 0.000 0.119 12.322
ENSG00000138758 E009 0.2536433 0.0160344981 1.169509e-01   4 76973010 76973070 61 + 0.000 0.212 13.257
ENSG00000138758 E010 0.3641952 0.0164566152 9.474185e-01   4 76974478 76974807 330 + 0.140 0.119 -0.271
ENSG00000138758 E011 0.1272623 0.0123467530 3.258496e-01   4 76985024 76985123 100 + 0.000 0.119 12.322
ENSG00000138758 E012 0.0000000       4 76987788 76987808 21 +      
ENSG00000138758 E013 0.1271363 0.0123582251 3.257661e-01   4 76987809 76987870 62 + 0.000 0.119 12.322
ENSG00000138758 E014 0.6181860 0.2318624089 3.806851e-01 6.671174e-01 4 76995781 76995938 158 + 0.140 0.289 1.313
ENSG00000138758 E015 9.4585416 0.0179177406 7.117050e-01 8.834798e-01 4 76996425 76996539 115 + 1.021 0.992 -0.108
ENSG00000138758 E016 21.7189681 0.0103455987 7.358505e-01 8.952002e-01 4 77005601 77005796 196 + 1.352 1.338 -0.047
ENSG00000138758 E017 0.1268540 0.0123021077 3.258325e-01   4 77009780 77009987 208 + 0.000 0.119 12.323
ENSG00000138758 E018 25.8589779 0.0126685900 8.192368e-02 2.944862e-01 4 77011735 77011921 187 + 1.462 1.345 -0.405
ENSG00000138758 E019 7.9491074 0.0017710185 6.316604e-02 2.528599e-01 4 77014856 77014870 15 + 1.005 0.824 -0.686
ENSG00000138758 E020 19.6912765 0.0024022492 1.036712e-01 3.365485e-01 4 77014871 77015017 147 + 1.344 1.240 -0.365
ENSG00000138758 E021 16.1327260 0.0009860003 7.471872e-01 9.001595e-01 4 77019165 77019261 97 + 1.230 1.216 -0.049
ENSG00000138758 E022 10.4199013 0.0014445591 5.275290e-01 7.794573e-01 4 77020502 77020531 30 + 1.066 1.019 -0.172
ENSG00000138758 E023 19.9363692 0.0007608383 5.072401e-02 2.227264e-01 4 77020532 77020670 139 + 1.356 1.232 -0.432
ENSG00000138758 E024 3.9218086 0.0194493346 2.091286e-01 4.934002e-01 4 77020671 77021639 969 + 0.607 0.781 0.729
ENSG00000138758 E025 17.9321650 0.0008170858 3.460912e-01 6.369878e-01 4 77028629 77028716 88 + 1.289 1.232 -0.199
ENSG00000138758 E026 19.6415136 0.0018428707 4.366704e-01 7.130732e-01 4 77028717 77028761 45 + 1.322 1.278 -0.153
ENSG00000138758 E027 30.0372415 0.0004678887 1.963740e-01 4.770391e-01 4 77030783 77030896 114 + 1.505 1.444 -0.211
ENSG00000138758 E028 22.6171274 0.0005964562 1.113185e-01 3.503853e-01 4 77030897 77030970 74 + 1.397 1.306 -0.318
ENSG00000138758 E029 20.7561948 0.0007382275 5.662477e-10 5.056292e-08 4 77030971 77032158 1188 + 1.120 1.529 1.429
ENSG00000138758 E030 56.4880274 0.0003014007 1.231924e-02 9.192390e-02 4 77034497 77034923 427 + 1.783 1.692 -0.309
ENSG00000138758 E031 18.3489991 0.0018751452 9.557802e-01 9.893112e-01 4 77034924 77035020 97 + 1.271 1.285 0.047
ENSG00000138758 E032 173.2275910 0.0029314885 2.099668e-01 4.944050e-01 4 77035021 77036769 1749 + 2.240 2.217 -0.077
ENSG00000138758 E033 11.6197733 0.0150541008 5.470650e-02 2.329497e-01 4 77036770 77036772 3 + 1.005 1.199 0.699
ENSG00000138758 E034 19.2382152 0.0012045942 2.848740e-01 5.786095e-01 4 77036773 77036837 65 + 1.263 1.345 0.287
ENSG00000138758 E035 216.4205653 0.0049404055 1.032214e-02 8.196614e-02 4 77036838 77038715 1878 + 2.293 2.375 0.275
ENSG00000138758 E036 2.2331957 0.0067188878 1.598272e-02 1.096480e-01 4 77039073 77039326 254 + 0.331 0.680 1.729
ENSG00000138758 E037 4.4633622 0.0035373413 6.551256e-04 1.076258e-02 4 77039743 77040384 642 + 0.516 0.933 1.729

Help

Please Click HERE to learn more details about the results from DEXseq.