ENSG00000139163

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000266517 ENSG00000139163 No_inf pgKDN_inf ETNK1 protein_coding protein_coding 41.44699 35.8924 47.71995 1.999501 0.6574795 0.4108148 25.424990 13.5237081 35.400717 1.5389636 3.2811272 1.3876289 0.60035833 0.38465 0.744450 0.359800 0.011896559 0.006395663 FALSE TRUE
ENST00000544191 ENSG00000139163 No_inf pgKDN_inf ETNK1 protein_coding retained_intron 41.44699 35.8924 47.71995 1.999501 0.6574795 0.4108148 5.448564 5.1035463 3.673120 1.5426899 0.5611801 -0.4733957 0.13176667 0.13705 0.076750 -0.060300 0.728666585 0.006395663   FALSE
ENST00000671733 ENSG00000139163 No_inf pgKDN_inf ETNK1 protein_coding protein_coding 41.44699 35.8924 47.71995 1.999501 0.6574795 0.4108148 2.407316 0.9784153 3.192875 0.7163472 2.0295947 1.6961781 0.05665833 0.02440 0.065600 0.041200 0.954044545 0.006395663 FALSE TRUE
ENST00000673188 ENSG00000139163 No_inf pgKDN_inf ETNK1 protein_coding protein_coding_CDS_not_defined 41.44699 35.8924 47.71995 1.999501 0.6574795 0.4108148 3.208913 8.4384101 0.000000 3.0147355 0.0000000 -9.7225361 0.09076667 0.24440 0.000000 -0.244400 0.006395663 0.006395663 FALSE TRUE
MSTRG.6179.11 ENSG00000139163 No_inf pgKDN_inf ETNK1 protein_coding   41.44699 35.8924 47.71995 1.999501 0.6574795 0.4108148 3.465779 6.4942695 3.484100 2.8758853 0.5847662 -0.8964660 0.08517500 0.17270 0.072575 -0.100125 0.846904163 0.006395663 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139163 E001 0.0000000       12 22625075 22625140 66 +      
ENSG00000139163 E002 0.0000000       12 22625141 22625141 1 +      
ENSG00000139163 E003 0.1265070 1.230336e-02 4.044751e-01   12 22625142 22625170 29 + 0.000 0.108 9.620
ENSG00000139163 E004 1.7971532 8.326578e-03 6.318305e-02 2.528599e-01 12 22625171 22625191 21 + 0.551 0.266 -1.596
ENSG00000139163 E005 14.0874259 9.728559e-04 2.336277e-04 4.751310e-03 12 22625192 22625356 165 + 1.285 0.988 -1.068
ENSG00000139163 E006 7.0185696 1.959921e-03 1.131708e-01 3.538614e-01 12 22625357 22625381 25 + 0.968 0.803 -0.633
ENSG00000139163 E007 19.6833620 3.485858e-03 1.242984e-03 1.768375e-02 12 22625382 22625550 169 + 1.402 1.170 -0.814
ENSG00000139163 E008 10.7126998 1.295159e-03 1.881016e-03 2.441066e-02 12 22625551 22625586 36 + 1.171 0.890 -1.033
ENSG00000139163 E009 0.7279785 1.400039e-01 6.800103e-01 8.678169e-01 12 22625814 22626200 387 + 0.268 0.194 -0.597
ENSG00000139163 E010 1.3321643 9.582802e-03 6.573023e-01 8.566141e-01 12 22640432 22643762 3331 + 0.396 0.328 -0.403
ENSG00000139163 E011 23.3144978 1.242418e-03 3.412403e-08 2.188401e-06 12 22643763 22643888 126 + 1.512 1.145 -1.282
ENSG00000139163 E012 28.2969222 1.722621e-03 1.283485e-06 5.787918e-05 12 22643889 22644022 134 + 1.573 1.279 -1.013
ENSG00000139163 E013 0.4883426 9.963112e-02 7.943857e-01   12 22644211 22644587 377 + 0.154 0.194 0.405
ENSG00000139163 E014 0.1265070 1.230336e-02 4.044751e-01   12 22646019 22646055 37 + 0.000 0.108 11.196
ENSG00000139163 E015 0.4977810 2.689831e-02 2.057729e-01   12 22656432 22656745 314 + 0.084 0.266 1.989
ENSG00000139163 E016 1.1973440 2.194602e-01 2.196182e-01 5.062430e-01 12 22656746 22657197 452 + 0.432 0.194 -1.596
ENSG00000139163 E017 21.9451559 2.898662e-03 4.304643e-04 7.751807e-03 12 22659014 22659154 141 + 1.451 1.210 -0.841
ENSG00000139163 E018 2.7468725 4.953447e-03 1.214174e-03 1.737932e-02 12 22659155 22660027 873 + 0.315 0.762 2.170
ENSG00000139163 E019 24.8445916 5.429075e-03 3.834745e-04 7.061220e-03 12 22661063 22661205 143 + 1.503 1.260 -0.845
ENSG00000139163 E020 0.7328886 1.461932e-02 7.341911e-01 8.944241e-01 12 22661206 22661228 23 + 0.214 0.266 0.404
ENSG00000139163 E021 3.9376347 3.957615e-03 1.390067e-01 3.964741e-01 12 22668598 22668700 103 + 0.600 0.783 0.767
ENSG00000139163 E022 2.6045654 6.350277e-03 3.182622e-02 1.685999e-01 12 22668701 22668722 22 + 0.396 0.694 1.404
ENSG00000139163 E023 5.0610950 2.771189e-03 2.261931e-02 1.369038e-01 12 22671086 22671271 186 + 0.644 0.905 1.048
ENSG00000139163 E024 20.7563801 1.436473e-03 1.914592e-01 4.710625e-01 12 22671272 22671355 84 + 1.372 1.286 -0.301
ENSG00000139163 E025 40.3340936 1.695580e-03 1.707791e-01 4.430614e-01 12 22673500 22673660 161 + 1.643 1.575 -0.231
ENSG00000139163 E026 0.1268540 1.233061e-02 4.044005e-01   12 22682281 22682339 59 + 0.000 0.108 11.196
ENSG00000139163 E027 30.2763082 6.430078e-04 1.230288e-02 9.189078e-02 12 22684483 22684556 74 + 1.550 1.411 -0.476
ENSG00000139163 E028 1108.9459066 4.574633e-05 1.367037e-23 5.015631e-21 12 22684882 22690666 5785 + 3.025 3.065 0.133

Help

Please Click HERE to learn more details about the results from DEXseq.