ENSG00000139433

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318348 ENSG00000139433 No_inf pgKDN_inf GLTP protein_coding protein_coding 24.14654 18.23937 31.05631 0.4280598 0.6372297 0.7675045 23.35590 16.01989 30.90385 1.0551707 0.5509283 0.9474892 0.95769167 0.8778 0.995275 0.117475 0.01797220 0.0179722 FALSE TRUE
MSTRG.7148.2 ENSG00000139433 No_inf pgKDN_inf GLTP protein_coding   24.14654 18.23937 31.05631 0.4280598 0.6372297 0.7675045 0.69425 2.08275 0.00000 0.9601915 0.0000000 -7.7092562 0.03806667 0.1142 0.000000 -0.114200 0.03164421 0.0179722 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139433 E001 0.6069838 0.2210709115 0.956467165 0.98965422 12 109850945 109850964 20 - 0.200 0.208 0.073
ENSG00000139433 E002 162.6569426 0.0001627836 0.007850288 0.06824765 12 109850965 109852260 1296 - 2.188 2.231 0.144
ENSG00000139433 E003 28.3166520 0.0005507122 0.107136113 0.34300600 12 109852261 109852544 284 - 1.494 1.403 -0.316
ENSG00000139433 E004 9.8962520 0.0013853891 0.120611636 0.36741418 12 109852545 109852554 10 - 1.083 0.939 -0.532
ENSG00000139433 E005 19.6113941 0.0201818926 0.251922578 0.54318351 12 109852555 109852664 110 - 1.344 1.245 -0.344
ENSG00000139433 E006 15.1535510 0.0149550369 0.481738257 0.74672761 12 109852665 109852733 69 - 1.225 1.162 -0.224
ENSG00000139433 E007 6.4124445 0.0021318154 0.477972919 0.74408981 12 109852734 109852737 4 - 0.893 0.815 -0.303
ENSG00000139433 E008 19.1092554 0.0007256701 0.477730722 0.74390063 12 109855619 109855738 120 - 1.277 1.322 0.155
ENSG00000139433 E009 9.2365582 0.0017370791 0.887200333 0.96229788 12 109855739 109855769 31 - 0.999 1.009 0.040
ENSG00000139433 E010 9.0727353 0.0018328638 0.472796340 0.73997862 12 109857526 109857582 57 - 1.023 0.954 -0.258
ENSG00000139433 E011 16.8017182 0.0084860772 0.278677623 0.57190362 12 109857583 109857659 77 - 1.277 1.189 -0.312
ENSG00000139433 E012 0.4889073 0.1223949543 0.663723837   12 109857855 109858139 285 - 0.143 0.208 0.657
ENSG00000139433 E013 0.1170040 0.0117051424 0.885084774   12 109858140 109858193 54 - 0.077 0.000 -7.443
ENSG00000139433 E014 13.6958796 0.0315925836 0.762838828 0.90745163 12 109858683 109858741 59 - 1.171 1.143 -0.100
ENSG00000139433 E015 12.7935205 0.0120791862 0.243867279 0.53390119 12 109880272 109880541 270 - 1.090 1.189 0.354

Help

Please Click HERE to learn more details about the results from DEXseq.