ENSG00000139436

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000320063 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding protein_coding 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 4.664924 5.029566 4.6334961 3.4437010 1.6938246 -0.1180882 0.10873333 0.096025 0.115600 0.019575 0.82658070 0.00980192 FALSE TRUE
ENST00000355312 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding protein_coding 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 7.507962 2.304383 12.8022092 2.3043827 2.8401766 2.4688199 0.19832500 0.048200 0.328250 0.280050 0.00980192 0.00980192 FALSE TRUE
ENST00000361006 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding protein_coding 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 6.092393 7.472641 4.3001637 3.0227034 2.4828492 -0.7958050 0.14933333 0.143850 0.109000 -0.034850 0.83593092 0.00980192 FALSE TRUE
ENST00000547815 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding protein_coding 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 2.514568 3.536876 2.9524899 0.4688180 0.2891484 -0.2597385 0.05740833 0.069125 0.075000 0.005875 0.98557923 0.00980192 FALSE TRUE
ENST00000548655 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding protein_coding_CDS_not_defined 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 2.142041 2.693977 1.6625747 0.5582045 0.2884933 -0.6930125 0.05115000 0.053375 0.042000 -0.011375 0.89699660 0.00980192   FALSE
ENST00000550480 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding retained_intron 41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 2.772623 3.870646 2.8531286 0.5926425 0.5836682 -0.4387043 0.06487500 0.075050 0.072250 -0.002800 0.99978069 0.00980192   FALSE
MSTRG.7159.1 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding   41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 7.612098 13.077331 5.4628887 1.8181067 1.8859108 -1.2577964 0.16876667 0.254775 0.137200 -0.117575 0.65202146 0.00980192 FALSE TRUE
MSTRG.7159.17 ENSG00000139436 No_inf pgKDN_inf GIT2 protein_coding   41.80209 51.27216 39.39885 1.341555 1.002105 -0.3799375 2.875812 6.796738 0.9293221 2.5078128 0.9293221 -2.8572716 0.06356667 0.133650 0.024325 -0.109325 0.30003667 0.00980192 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139436 E001 0.0000000       12 109929804 109929814 11 -      
ENSG00000139436 E002 0.0000000       12 109929815 109931153 1339 -      
ENSG00000139436 E003 24.0649762 0.0073020464 1.137976e-01 0.355182883 12 109931154 109932254 1101 - 1.332 1.443 0.386
ENSG00000139436 E004 46.8595277 0.0003688227 4.574879e-01 0.729357130 12 109932255 109932614 360 - 1.692 1.665 -0.093
ENSG00000139436 E005 28.1910879 0.0004875566 4.656084e-01 0.734573140 12 109932615 109932977 363 - 1.482 1.447 -0.123
ENSG00000139436 E006 0.0000000       12 109932978 109933037 60 -      
ENSG00000139436 E007 0.0000000       12 109933038 109933056 19 -      
ENSG00000139436 E008 0.0000000       12 109933057 109933095 39 -      
ENSG00000139436 E009 0.0000000       12 109933096 109933111 16 -      
ENSG00000139436 E010 0.0000000       12 109933112 109933190 79 -      
ENSG00000139436 E011 0.0000000       12 109934022 109934036 15 -      
ENSG00000139436 E012 0.0000000       12 109934037 109934039 3 -      
ENSG00000139436 E013 0.0000000       12 109934040 109934085 46 -      
ENSG00000139436 E014 18.7641259 0.0008099259 7.319002e-01 0.893386527 12 109938380 109938534 155 - 1.304 1.285 -0.067
ENSG00000139436 E015 13.1483799 0.0069119979 7.842921e-01 0.916838543 12 109938535 109938568 34 - 1.133 1.161 0.099
ENSG00000139436 E016 0.1271363 0.0123375009 6.213600e-01   12 109938569 109938808 240 - 0.000 0.089 9.939
ENSG00000139436 E017 1.1264796 0.0113166907 1.367915e-01 0.393661906 12 109938809 109939022 214 - 0.183 0.415 1.609
ENSG00000139436 E018 16.7407979 0.0012479126 1.993270e-01 0.480942176 12 109939165 109939239 75 - 1.293 1.206 -0.304
ENSG00000139436 E019 7.5377598 0.0264303479 1.253584e-01 0.375334900 12 109939240 109939247 8 - 1.019 0.841 -0.667
ENSG00000139436 E020 6.4250989 0.0102350424 2.834789e-01 0.577210508 12 109939248 109939685 438 - 0.796 0.920 0.479
ENSG00000139436 E021 10.2830238 0.0187821909 6.862005e-02 0.264486093 12 109939754 109940501 748 - 0.935 1.125 0.698
ENSG00000139436 E022 2.4841657 0.0066532107 1.402412e-01 0.398512519 12 109942842 109943021 180 - 0.410 0.623 1.024
ENSG00000139436 E023 11.5954785 0.0241072280 2.527273e-01 0.544117961 12 109945260 109945349 90 - 1.157 1.043 -0.411
ENSG00000139436 E024 11.3046792 0.0028011501 1.536903e-02 0.106876845 12 109947256 109947321 66 - 1.188 0.986 -0.732
ENSG00000139436 E025 21.5609453 0.0006722650 3.935177e-03 0.041977819 12 109947322 109947504 183 - 1.439 1.264 -0.609
ENSG00000139436 E026 1.7214657 0.0088564122 7.951248e-01 0.922163657 12 109947505 109947944 440 - 0.410 0.451 0.216
ENSG00000139436 E027 0.2451451 0.0165007818 9.093038e-01   12 109947945 109948061 117 - 0.101 0.089 -0.199
ENSG00000139436 E028 23.8725188 0.0146831276 6.603354e-05 0.001670475 12 109948062 109948846 785 - 1.188 1.509 1.118
ENSG00000139436 E029 2.1232434 0.0890670909 1.036207e-01 0.336465519 12 109950694 109951166 473 - 0.312 0.599 1.501
ENSG00000139436 E030 15.7181705 0.0016022558 9.029503e-01 0.968864658 12 109951167 109951211 45 - 1.224 1.218 -0.018
ENSG00000139436 E031 22.2482524 0.0007010297 7.790230e-01 0.914998379 12 109951212 109951316 105 - 1.352 1.373 0.073
ENSG00000139436 E032 0.0000000       12 109952680 109953091 412 -      
ENSG00000139436 E033 4.4300952 0.0760856818 8.546947e-01 0.948734319 12 109953092 109953234 143 - 0.716 0.746 0.123
ENSG00000139436 E034 0.4814816 0.0153283304 2.537849e-01   12 109953235 109954550 1316 - 0.252 0.089 -1.784
ENSG00000139436 E035 16.9076857 0.0044554814 6.111929e-01 0.830870497 12 109959847 109959958 112 - 1.269 1.236 -0.115
ENSG00000139436 E036 28.9617472 0.0100729391 9.811887e-01 0.998084405 12 109961278 109961375 98 - 1.471 1.477 0.022
ENSG00000139436 E037 21.6195073 0.0025776771 8.203658e-01 0.934852028 12 109961613 109961650 38 - 1.342 1.360 0.064
ENSG00000139436 E038 16.0466303 0.0008613915 4.494657e-01 0.723156004 12 109961651 109961685 35 - 1.256 1.206 -0.177
ENSG00000139436 E039 14.1199616 0.0009713249 9.576967e-01 0.989905942 12 109965526 109965574 49 - 1.173 1.181 0.027
ENSG00000139436 E040 4.5439267 0.0030004833 9.626099e-01 0.991887985 12 109965575 109965577 3 - 0.737 0.746 0.036
ENSG00000139436 E041 0.0000000       12 109967314 109967319 6 -      
ENSG00000139436 E042 5.2690729 0.0026084929 7.448930e-01 0.898972035 12 109967458 109967503 46 - 0.813 0.780 -0.132
ENSG00000139436 E043 0.0000000       12 109980952 109981046 95 -      
ENSG00000139436 E044 5.8822011 0.0026528964 3.877631e-04 0.007113475 12 109981047 109983180 2134 - 0.559 0.976 1.689
ENSG00000139436 E045 6.3891016 0.0023789173 9.791472e-01 0.997390006 12 109983373 109983503 131 - 0.863 0.869 0.024
ENSG00000139436 E046 0.0000000       12 109983608 109983694 87 -      
ENSG00000139436 E047 15.5407981 0.0267119380 3.233288e-01 0.615980721 12 109988963 109989068 106 - 1.263 1.174 -0.313
ENSG00000139436 E048 20.8541854 0.0010538575 6.181040e-01 0.834762782 12 109989690 109989802 113 - 1.352 1.324 -0.097
ENSG00000139436 E049 16.4845468 0.0011054240 5.908075e-01 0.818868069 12 109991627 109991760 134 - 1.217 1.259 0.147
ENSG00000139436 E050 0.8793832 0.0183897443 7.654649e-02 0.282887363 12 109991761 109992088 328 - 0.101 0.375 2.386
ENSG00000139436 E051 0.1187032 0.0118819476 4.648466e-01   12 109996099 109996172 74 - 0.101 0.000 -10.442
ENSG00000139436 E052 11.2515718 0.0022163984 2.686913e-01 0.562256357 12 109996173 109996389 217 - 1.133 1.043 -0.324

Help

Please Click HERE to learn more details about the results from DEXseq.