ENSG00000139620

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000420613 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding protein_coding 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 2.1928476 3.2200633 1.7369609 0.3178961 1.0298925 -0.8867151 0.17916667 0.268075 0.150850 -0.117225 6.543152e-01 5.113543e-06 FALSE TRUE
ENST00000546701 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding nonsense_mediated_decay 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 0.6913620 0.9602824 0.6049156 0.5683342 0.6049156 -0.6580163 0.06500000 0.088275 0.069325 -0.018950 8.369115e-01 5.113543e-06 TRUE TRUE
ENST00000548147 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding nonsense_mediated_decay 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 0.7217096 0.0000000 0.7419006 0.0000000 0.7419006 6.2324701 0.05894167 0.000000 0.063750 0.063750 8.354346e-01 5.113543e-06 FALSE TRUE
ENST00000548254 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding retained_intron 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 0.7577348 1.2730303 0.0000000 1.2730303 0.0000000 -7.0034114 0.03899167 0.067900 0.000000 -0.067900 8.480980e-01 5.113543e-06 FALSE FALSE
ENST00000548701 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding protein_coding_CDS_not_defined 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 2.5325113 0.7508681 2.3912097 0.4556931 0.8074944 1.6580431 0.18915833 0.069150 0.202475 0.133325 6.625060e-01 5.113543e-06 FALSE TRUE
ENST00000549463 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding protein_coding_CDS_not_defined 12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 1.7865888 5.3597664 0.0000000 1.5816493 0.0000000 -9.0687155 0.13423333 0.402700 0.000000 -0.402700 5.113543e-06 5.113543e-06   FALSE
MSTRG.6409.5 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding   12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 1.0420649 0.8799100 1.3923109 0.4310949 1.1281269 0.6560749 0.09392500 0.061200 0.153825 0.092625 9.496770e-01 5.113543e-06 TRUE TRUE
MSTRG.6409.6 ENSG00000139620 No_inf pgKDN_inf KANSL2 protein_coding   12.76508 12.89776 11.07903 1.954776 0.8192795 -0.219105 2.6006237 0.4538400 3.3563304 0.4538400 1.8734760 2.8594775 0.20582500 0.042725 0.287925 0.245200 3.371454e-01 5.113543e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139620 E001 0.0000000       12 48653211 48653400 190 -      
ENSG00000139620 E002 0.0000000       12 48653401 48653401 1 -      
ENSG00000139620 E003 0.3804973 0.015914841 0.098813053   12 48653402 48653438 37 - 0.000 0.242 10.552
ENSG00000139620 E004 2.4767702 0.033257967 0.187760416 0.46595823 12 48653439 48653510 72 - 0.429 0.626 0.937
ENSG00000139620 E005 6.8806118 0.003056750 0.529221730 0.78058975 12 48653511 48653688 178 - 0.861 0.927 0.251
ENSG00000139620 E006 2.1896035 0.025880887 0.402197156 0.68535280 12 48653689 48653709 21 - 0.563 0.438 -0.608
ENSG00000139620 E007 6.5841977 0.002411444 0.310087274 0.60337135 12 48653710 48653833 124 - 0.928 0.827 -0.386
ENSG00000139620 E008 5.3067431 0.002822128 0.144652758 0.40482114 12 48653834 48653868 35 - 0.707 0.873 0.657
ENSG00000139620 E009 4.4646891 0.003363849 0.036247489 0.18289229 12 48653869 48653888 20 - 0.590 0.843 1.044
ENSG00000139620 E010 21.2185665 0.001582791 0.465263898 0.73437220 12 48653889 48654175 287 - 1.322 1.369 0.161
ENSG00000139620 E011 3.6633204 0.004127677 0.761501771 0.90690124 12 48654941 48654952 12 - 0.686 0.651 -0.148
ENSG00000139620 E012 7.4515688 0.002028361 0.577635085 0.81129224 12 48654953 48655060 108 - 0.952 0.901 -0.193
ENSG00000139620 E013 0.6263978 0.014293789 0.164425321 0.43371229 12 48658632 48658674 43 - 0.094 0.300 2.044
ENSG00000139620 E014 5.7542425 0.002578389 0.947356330 0.98606193 12 48660366 48660467 102 - 0.832 0.827 -0.017
ENSG00000139620 E015 9.9546184 0.042369811 0.418005571 0.69769061 12 48660468 48660619 152 - 0.986 1.086 0.366
ENSG00000139620 E016 0.7331709 0.015020982 0.979577410 0.99759190 12 48661195 48661243 49 - 0.236 0.242 0.044
ENSG00000139620 E017 1.7237666 0.007959524 0.566298133 0.80464523 12 48662560 48662654 95 - 0.389 0.475 0.459
ENSG00000139620 E018 6.1501100 0.002726992 0.003436119 0.03825049 12 48667693 48667789 97 - 0.986 0.675 -1.219
ENSG00000139620 E019 6.4922773 0.002372775 0.958256333 0.99001220 12 48669106 48669272 167 - 0.876 0.873 -0.010
ENSG00000139620 E020 4.3107257 0.053320627 0.481008549 0.74618791 12 48671799 48671857 59 - 0.664 0.776 0.459
ENSG00000139620 E021 3.2716995 0.009139827 0.097113954 0.32453956 12 48671858 48671918 61 - 0.727 0.510 -0.956
ENSG00000139620 E022 3.5164117 0.004322395 0.105378442 0.33963672 12 48671919 48671962 44 - 0.747 0.542 -0.882
ENSG00000139620 E023 4.6190651 0.020537364 0.150118468 0.41262651 12 48679036 48679150 115 - 0.832 0.651 -0.734
ENSG00000139620 E024 0.0000000       12 48679151 48679238 88 -      
ENSG00000139620 E025 4.8883560 0.009261015 0.804735037 0.92770288 12 48679655 48679760 106 - 0.783 0.758 -0.100
ENSG00000139620 E026 4.5264311 0.066160167 0.954089612 0.98869526 12 48679761 48679833 73 - 0.747 0.738 -0.034
ENSG00000139620 E027 0.2357071 0.015891899 0.250149414   12 48679834 48680058 225 - 0.171 0.000 -13.111
ENSG00000139620 E028 0.0000000       12 48681224 48681381 158 -      
ENSG00000139620 E029 5.0196492 0.033000977 0.975934319 0.99593275 12 48681382 48681423 42 - 0.783 0.776 -0.026
ENSG00000139620 E030 8.9388952 0.001717924 0.986364986 0.99933518 12 48681424 48681570 147 - 0.996 0.998 0.005
ENSG00000139620 E031 3.4287416 0.004342611 0.951387618 0.98777913 12 48681571 48681641 71 - 0.641 0.651 0.044
ENSG00000139620 E032 0.0000000       12 48681642 48681857 216 -      
ENSG00000139620 E033 0.3716522 0.180911346 0.610091259   12 48681858 48681971 114 - 0.094 0.175 1.043
ENSG00000139620 E034 0.4892828 0.071865457 0.986881682   12 48681972 48682065 94 - 0.171 0.175 0.044
ENSG00000139620 E035 0.0000000       12 48682066 48682186 121 -      
ENSG00000139620 E036 0.6243526 0.051555966 0.174593523 0.44840605 12 48682187 48682238 52 - 0.094 0.300 2.044

Help

Please Click HERE to learn more details about the results from DEXseq.