ENSG00000139626

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000267082 ENSG00000139626 No_inf pgKDN_inf ITGB7 protein_coding protein_coding 172.9817 162.9005 157.7368 5.310413 3.532271 -0.04646934 108.44578 88.53600 110.418678 1.794002 4.217321 0.3186159 0.62780000 0.545025 0.700325 0.155300 0.006372943 0.006372943 FALSE TRUE
ENST00000422257 ENSG00000139626 No_inf pgKDN_inf ITGB7 protein_coding protein_coding 172.9817 162.9005 157.7368 5.310413 3.532271 -0.04646934 25.83736 27.75599 18.104144 6.223091 5.212982 -0.6162022 0.14775833 0.170350 0.112900 -0.057450 0.714186585 0.006372943 FALSE TRUE
ENST00000551319 ENSG00000139626 No_inf pgKDN_inf ITGB7 protein_coding protein_coding 172.9817 162.9005 157.7368 5.310413 3.532271 -0.04646934 13.73989 20.61560 8.145324 4.940751 2.970225 -1.3386221 0.07900833 0.123950 0.050775 -0.073175 0.304598889 0.006372943 FALSE FALSE
MSTRG.6560.2 ENSG00000139626 No_inf pgKDN_inf ITGB7 protein_coding   172.9817 162.9005 157.7368 5.310413 3.532271 -0.04646934 16.80027 17.96941 16.758736 6.358086 6.023844 -0.1005716 0.09995000 0.112075 0.108875 -0.003200 1.000000000 0.006372943 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139626 E001 0.0000000       12 53191319 53191322 4 -      
ENSG00000139626 E002 0.0000000       12 53191323 53191323 1 -      
ENSG00000139626 E003 0.0000000       12 53191324 53191370 47 -      
ENSG00000139626 E004 0.0000000       12 53191371 53191556 186 -      
ENSG00000139626 E005 0.0000000       12 53191557 53191631 75 -      
ENSG00000139626 E006 0.0000000       12 53191632 53191636 5 -      
ENSG00000139626 E007 0.0000000       12 53191637 53191731 95 -      
ENSG00000139626 E008 0.0000000       12 53191859 53192019 161 -      
ENSG00000139626 E009 0.0000000       12 53192330 53192538 209 -      
ENSG00000139626 E010 0.0000000       12 53192691 53192910 220 -      
ENSG00000139626 E011 0.0000000       12 53192968 53193139 172 -      
ENSG00000139626 E012 0.0000000       12 53193140 53193363 224 -      
ENSG00000139626 E013 0.0000000       12 53193677 53193707 31 -      
ENSG00000139626 E014 0.0000000       12 53193708 53193901 194 -      
ENSG00000139626 E015 0.0000000       12 53194198 53194344 147 -      
ENSG00000139626 E016 0.0000000       12 53194345 53194458 114 -      
ENSG00000139626 E017 62.0922373 0.0002424497 0.360842929 0.65039276 12 53195374 53195463 90 - 1.780 1.816 0.122
ENSG00000139626 E018 66.5820990 0.0002200391 0.425359557 0.70445687 12 53195626 53195653 28 - 1.843 1.816 -0.092
ENSG00000139626 E019 99.1773459 0.0001970695 0.401182276 0.68440186 12 53195654 53195721 68 - 2.012 1.989 -0.078
ENSG00000139626 E020 113.1169778 0.0003229144 0.495305883 0.75652991 12 53196041 53196100 60 - 2.046 2.066 0.070
ENSG00000139626 E021 122.2130508 0.0001544422 0.280583560 0.57391511 12 53196101 53196193 93 - 2.074 2.104 0.101
ENSG00000139626 E022 45.0884415 0.0003196440 0.142007466 0.40093152 12 53196194 53196199 6 - 1.627 1.693 0.227
ENSG00000139626 E023 2.6968292 0.0083874221 0.928903120 0.97898311 12 53196332 53196578 247 - 0.573 0.562 -0.049
ENSG00000139626 E024 49.1603890 0.0003031934 0.103518919 0.33628734 12 53196579 53196593 15 - 1.661 1.732 0.240
ENSG00000139626 E025 137.0396796 0.0001300936 0.059078310 0.24388286 12 53196594 53196820 227 - 2.113 2.162 0.163
ENSG00000139626 E026 18.1124427 0.0422562286 0.007134525 0.06384896 12 53196821 53197492 672 - 1.095 1.399 1.072
ENSG00000139626 E027 70.6042710 0.0002458837 0.312170249 0.60556739 12 53197493 53197590 98 - 1.872 1.838 -0.114
ENSG00000139626 E028 56.8848776 0.0002557681 0.017490561 0.11597282 12 53197591 53197663 73 - 1.808 1.716 -0.310
ENSG00000139626 E029 0.0000000       12 53197664 53197709 46 -      
ENSG00000139626 E030 79.9156745 0.0002019204 0.351678080 0.64191842 12 53197750 53197871 122 - 1.923 1.893 -0.098
ENSG00000139626 E031 39.9715226 0.0011357165 0.299724150 0.59260822 12 53197872 53197886 15 - 1.637 1.589 -0.164
ENSG00000139626 E032 66.2120266 0.0002198244 0.451174156 0.72429309 12 53197887 53197951 65 - 1.840 1.815 -0.087
ENSG00000139626 E033 134.5194206 0.0001509349 0.826780465 0.93726525 12 53200243 53200446 204 - 2.133 2.130 -0.013
ENSG00000139626 E034 43.5955043 0.0003321907 0.091533673 0.31414426 12 53201072 53201117 46 - 1.686 1.612 -0.252
ENSG00000139626 E035 42.2916574 0.0003684592 0.224114028 0.51171505 12 53201118 53201146 29 - 1.663 1.610 -0.183
ENSG00000139626 E036 51.1633655 0.0002861394 0.432346911 0.70977379 12 53201147 53201194 48 - 1.733 1.702 -0.105
ENSG00000139626 E037 0.1268540 0.0123498202 0.559340928   12 53201195 53201300 106 - 0.000 0.094 9.254
ENSG00000139626 E038 0.1187032 0.0118513192 0.517868962   12 53206674 53206804 131 - 0.097 0.000 -9.458
ENSG00000139626 E039 35.8230787 0.0003983525 0.622237665 0.83723596 12 53207202 53207293 92 - 1.552 1.578 0.089

Help

Please Click HERE to learn more details about the results from DEXseq.