ENSG00000139668

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000298125 ENSG00000139668 No_inf pgKDN_inf WDFY2 protein_coding protein_coding 29.6379 20.0477 40.74067 5.143342 12.20729 1.022668 1.897834 0.8017593 2.546539 0.3049791 0.2574627 1.6550682 0.0858000 0.049175 0.099525 0.050350 0.81247383 0.01013575 FALSE TRUE
MSTRG.7836.3 ENSG00000139668 No_inf pgKDN_inf WDFY2 protein_coding   29.6379 20.0477 40.74067 5.143342 12.20729 1.022668 6.167698 6.1559118 4.280374 0.4648171 0.4886211 -0.5232109 0.2877417 0.377600 0.143475 -0.234125 0.28345291 0.01013575 FALSE TRUE
MSTRG.7836.4 ENSG00000139668 No_inf pgKDN_inf WDFY2 protein_coding   29.6379 20.0477 40.74067 5.143342 12.20729 1.022668 1.795218 0.0000000 3.433096 0.0000000 0.8960846 8.4275625 0.0700500 0.000000 0.152275 0.152275 0.01013575 0.01013575 TRUE TRUE
MSTRG.7836.6 ENSG00000139668 No_inf pgKDN_inf WDFY2 protein_coding   29.6379 20.0477 40.74067 5.143342 12.20729 1.022668 17.109385 8.7506142 28.941093 5.0524706 12.7014988 1.7245139 0.4243583 0.302900 0.561150 0.258250 0.81172125 0.01013575   FALSE
MSTRG.7836.7 ENSG00000139668 No_inf pgKDN_inf WDFY2 protein_coding   29.6379 20.0477 40.74067 5.143342 12.20729 1.022668 2.521903 4.1560644 1.440297 0.3826144 0.3404248 -1.5223369 0.1244083 0.257750 0.040025 -0.217725 0.01521582 0.01013575 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139668 E001 0.2459004 0.0159868163 0.9154422019   13 51584455 51584461 7 + 0.101 0.089 -0.204
ENSG00000139668 E002 0.2459004 0.0159868163 0.9154422019   13 51584462 51584470 9 + 0.101 0.089 -0.204
ENSG00000139668 E003 3.5790382 0.1725071008 0.7662553762 0.909209695 13 51584471 51584542 72 + 0.618 0.688 0.299
ENSG00000139668 E004 13.9696843 0.0010489853 0.5819626110 0.813872283 13 51584543 51584824 282 + 1.196 1.153 -0.153
ENSG00000139668 E005 3.5865670 0.0040957425 0.3505798455 0.640802727 13 51586025 51592586 6562 + 0.590 0.708 0.507
ENSG00000139668 E006 5.4753188 0.0027039383 0.1340475961 0.389008504 13 51660596 51660663 68 + 0.894 0.727 -0.656
ENSG00000139668 E007 4.7558512 0.1283534805 0.4934295274 0.755375327 13 51675170 51675243 74 + 0.831 0.688 -0.576
ENSG00000139668 E008 6.5569410 0.0268854972 0.0649954264 0.256829316 13 51703596 51703650 55 + 0.985 0.763 -0.856
ENSG00000139668 E009 11.4273568 0.0012830425 0.0109277447 0.085207023 13 51719198 51719348 151 + 1.196 0.985 -0.763
ENSG00000139668 E010 8.8571435 0.0016228897 0.0095940351 0.078270260 13 51727678 51727790 113 + 1.108 0.868 -0.888
ENSG00000139668 E011 10.5464525 0.0014044001 0.0017153530 0.022670295 13 51739049 51739147 99 + 1.189 0.919 -0.985
ENSG00000139668 E012 6.2752988 0.0029474466 0.0003651432 0.006816765 13 51739148 51739175 28 + 1.030 0.646 -1.506
ENSG00000139668 E013 10.6978021 0.0111846869 0.0313688727 0.167116076 13 51751310 51751415 106 + 1.166 0.964 -0.734
ENSG00000139668 E014 1.4796241 0.0105514116 0.7349007518 0.894819101 13 51752843 51752862 20 + 0.364 0.414 0.282
ENSG00000139668 E015 5.8175602 0.0293957674 0.1338351610 0.388770806 13 51752863 51752982 120 + 0.716 0.907 0.750
ENSG00000139668 E016 1.2310514 0.0123199565 0.6811505006 0.868265253 13 51752983 51752986 4 + 0.312 0.374 0.381
ENSG00000139668 E017 14.8428560 0.0010119054 0.0156964784 0.108410022 13 51752987 51753670 684 + 1.090 1.269 0.637
ENSG00000139668 E018 2.5757692 0.0151378154 0.9229722891 0.976329510 13 51753671 51753738 68 + 0.560 0.545 -0.066
ENSG00000139668 E019 8.5964269 0.0016572320 0.0004485746 0.008027015 13 51754101 51754397 297 + 0.758 1.101 1.299
ENSG00000139668 E020 11.6809957 0.0012341191 0.6395633629 0.846712252 13 51755358 51755459 102 + 1.080 1.117 0.132
ENSG00000139668 E021 16.4931744 0.0008991716 0.3381807855 0.630010794 13 51756332 51756462 131 + 1.203 1.269 0.230
ENSG00000139668 E022 11.9190944 0.0027369740 0.8089509599 0.929444482 13 51758192 51758300 109 + 1.099 1.117 0.065
ENSG00000139668 E023 103.2063137 0.0003836588 0.0028985314 0.033662660 13 51759740 51767709 7970 + 1.975 2.045 0.234

Help

Please Click HERE to learn more details about the results from DEXseq.