ENSG00000139880

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397359 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding protein_coding 39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 6.180401 5.209540 6.5055324 1.0384879 0.6478208 0.3199603 0.20722500 0.073625 0.271650 0.198025 0.005621524 0.001330878 TRUE TRUE
ENST00000485922 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding protein_coding_CDS_not_defined 39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 12.491636 30.471364 1.9137567 0.7349399 1.1252355 -3.9859292 0.23769167 0.427300 0.078400 -0.348900 0.023816966 0.001330878 TRUE TRUE
ENST00000487137 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding protein_coding 39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 3.943805 0.949847 6.5062987 0.9498470 0.7206311 2.7631764 0.15673333 0.013575 0.272150 0.258575 0.001330878 0.001330878 TRUE TRUE
MSTRG.8275.10 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding   39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 2.959283 5.998319 1.6302005 2.1908006 0.9903889 -1.8730893 0.06656667 0.083050 0.066150 -0.016900 0.851122853 0.001330878 FALSE TRUE
MSTRG.8275.2 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding   39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 3.357140 9.121676 0.8127108 3.0674867 0.6500514 -3.4724225 0.05536667 0.125700 0.034825 -0.090875 0.398519230 0.001330878 TRUE TRUE
MSTRG.8275.6 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding   39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 8.032209 12.982187 5.1129233 1.3225685 0.1717293 -1.3426052 0.21424167 0.182725 0.213600 0.030875 0.845785969 0.001330878 TRUE TRUE
MSTRG.8275.7 ENSG00000139880 No_inf pgKDN_inf CDH24 protein_coding   39.89964 71.33368 23.97265 1.364543 0.4151648 -1.572795 2.285795 6.090456 0.5851867 2.2750377 0.2692793 -3.3575029 0.03968333 0.087125 0.024550 -0.062575 0.765192265 0.001330878 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000139880 E001 0.0000000       14 23047062 23047066 5 -      
ENSG00000139880 E002 0.2543986 0.0160396141 1.000000e+00   14 23047067 23047132 66 - 0.000 0.105 8.843
ENSG00000139880 E003 0.7621583 0.0132224397 1.817950e-01 4.577894e-01 14 23047133 23047135 3 - 0.000 0.260 12.566
ENSG00000139880 E004 1.8974184 0.0089143417 7.996852e-02 2.902633e-01 14 23047136 23047149 14 - 0.158 0.465 2.128
ENSG00000139880 E005 3.2552607 0.0467083755 6.159471e-01 8.334366e-01 14 23047150 23047159 10 - 0.504 0.588 0.392
ENSG00000139880 E006 3.5076455 0.0359214365 4.821177e-01 7.470491e-01 14 23047160 23047160 1 - 0.504 0.618 0.523
ENSG00000139880 E007 5.1390520 0.0092647388 3.019258e-01 5.951993e-01 14 23047161 23047164 4 - 0.609 0.752 0.601
ENSG00000139880 E008 70.4416066 0.0002468824 4.269359e-01 7.055281e-01 14 23047165 23047374 210 - 1.804 1.769 -0.118
ENSG00000139880 E009 43.1823372 0.0019864024 9.692466e-01 9.936412e-01 14 23047461 23047513 53 - 1.572 1.568 -0.016
ENSG00000139880 E010 91.8931407 0.0001731840 1.117435e-01 3.511492e-01 14 23047514 23047659 146 - 1.846 1.903 0.189
ENSG00000139880 E011 151.2821384 0.0001713601 9.622686e-01 9.917637e-01 14 23047660 23048163 504 - 2.106 2.105 -0.004
ENSG00000139880 E012 93.8620937 0.0001989737 8.795005e-01 9.593376e-01 14 23048164 23048479 316 - 1.897 1.900 0.010
ENSG00000139880 E013 67.4328500 0.0002630601 4.923513e-02 2.187354e-01 14 23049027 23049275 249 - 1.692 1.776 0.284
ENSG00000139880 E014 41.5072294 0.0003937644 3.359675e-01 6.278459e-01 14 23049627 23049738 112 - 1.512 1.563 0.173
ENSG00000139880 E015 49.5607442 0.0003263637 8.224756e-01 9.355712e-01 14 23049822 23049943 122 - 1.621 1.629 0.029
ENSG00000139880 E016 87.5945833 0.0001846386 3.045717e-21 9.075565e-19 14 23049944 23050519 576 - 1.507 1.936 1.456
ENSG00000139880 E017 113.1874937 0.0002256192 5.138234e-09 3.843627e-07 14 23050520 23051439 920 - 1.813 2.019 0.693
ENSG00000139880 E018 31.3188232 0.0032177539 6.011529e-02 2.459983e-01 14 23051440 23051969 530 - 1.524 1.404 -0.413
ENSG00000139880 E019 20.8686462 0.0071550154 5.760355e-02 2.400548e-01 14 23051970 23052083 114 - 1.376 1.227 -0.522
ENSG00000139880 E020 39.6603877 0.0039646736 4.321187e-04 7.773813e-03 14 23052473 23052609 137 - 1.680 1.479 -0.686
ENSG00000139880 E021 63.1256839 0.0002885149 3.219662e-03 3.640446e-02 14 23053496 23053749 254 - 1.824 1.699 -0.424
ENSG00000139880 E022 38.1203625 0.0040206065 9.712363e-03 7.883500e-02 14 23054141 23054328 188 - 1.630 1.477 -0.522
ENSG00000139880 E023 41.8149678 0.0093853353 1.007032e-02 8.069124e-02 14 23054506 23054673 168 - 1.676 1.513 -0.556
ENSG00000139880 E024 37.5733931 0.0004845918 5.291208e-04 9.123730e-03 14 23054747 23054866 120 - 1.647 1.461 -0.636
ENSG00000139880 E025 73.7861293 0.0002195445 3.472897e-07 1.794131e-05 14 23055059 23055353 295 - 1.939 1.745 -0.654
ENSG00000139880 E026 33.0677271 0.0004190917 9.240283e-01 9.769381e-01 14 23055533 23055857 325 - 1.463 1.455 -0.028
ENSG00000139880 E027 7.8365196 0.0789519975 6.628738e-01 8.594862e-01 14 23057403 23057612 210 - 0.926 0.863 -0.242

Help

Please Click HERE to learn more details about the results from DEXseq.