ENSG00000140262

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000267811 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 12.145500 10.857943 17.564828 3.774163 1.3629178 0.6934317 0.32356667 0.166300 0.505600 0.339300 0.2283326 0.0311762 FALSE TRUE
ENST00000343827 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 1.901318 0.000000 4.184161 0.000000 2.5015259 8.7122385 0.06453333 0.000000 0.116225 0.116225 0.3610629 0.0311762 FALSE TRUE
ENST00000559710 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 2.847938 4.735082 1.626339 1.668550 1.6263392 -1.5359611 0.06064167 0.087300 0.049100 -0.038200 0.4698614 0.0311762 FALSE TRUE
ENST00000560190 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding_CDS_not_defined 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 2.986842 6.556219 1.784347 2.622852 1.7843466 -1.8716043 0.05880833 0.097800 0.049750 -0.048050 0.4468407 0.0311762 FALSE FALSE
ENST00000560836 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 10.960724 12.337705 0.000000 12.337705 0.0000000 -10.2700273 0.10494167 0.113250 0.000000 -0.113250 0.9844160 0.0311762   FALSE
ENST00000560948 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding protein_coding 48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 2.221753 3.584481 1.578013 1.500864 0.6189077 -1.1785609 0.05190000 0.048325 0.044225 -0.004100 0.9350711 0.0311762   FALSE
MSTRG.9652.1 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding   48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 3.484546 5.300698 2.266738 1.159376 1.0103177 -1.2219332 0.08300833 0.091100 0.065625 -0.025475 0.8402365 0.0311762 FALSE TRUE
MSTRG.9652.17 ENSG00000140262 No_inf pgKDN_inf TCF12 protein_coding   48.18892 67.81503 34.88967 13.73504 0.6903073 -0.9586043 6.851029 16.696636 2.541564 1.637085 2.5415643 -2.7109674 0.13157500 0.267150 0.073725 -0.193425 0.0311762 0.0311762 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140262 E001 0.7432757 0.0136828394 8.183737e-01 0.933939748 15 56918602 56918622 21 + 0.208 0.250 0.345
ENSG00000140262 E002 0.8701297 0.0130882407 6.078584e-01 0.829175306 15 56918623 56918624 2 + 0.208 0.296 0.667
ENSG00000140262 E003 1.7136588 0.0273850717 3.786654e-01 0.665606413 15 56918625 56918643 19 + 0.498 0.374 -0.655
ENSG00000140262 E004 3.2925743 0.0043819197 6.683663e-02 0.260497661 15 56918644 56918674 31 + 0.749 0.524 -0.977
ENSG00000140262 E005 3.6561054 0.0038532287 4.005112e-02 0.193958622 15 56918675 56918691 17 + 0.794 0.548 -1.042
ENSG00000140262 E006 10.6820873 0.0012813288 8.253007e-02 0.295936216 15 56918692 56918831 140 + 1.133 0.999 -0.489
ENSG00000140262 E007 10.7026464 0.0013657046 2.750667e-01 0.568560531 15 56918832 56918906 75 + 1.103 1.024 -0.288
ENSG00000140262 E008 0.1272623 0.0123494294 9.542608e-01   15 56919148 56919228 81 + 0.000 0.077 11.266
ENSG00000140262 E009 0.3724725 0.0166599132 9.713331e-01   15 56919474 56919516 43 + 0.116 0.143 0.345
ENSG00000140262 E010 3.0900423 0.0294487241 8.434323e-01 0.944043462 15 56919517 56919891 375 + 0.610 0.594 -0.070
ENSG00000140262 E011 8.0908151 0.0017280413 8.369097e-02 0.298392856 15 56919892 56919901 10 + 1.035 0.883 -0.567
ENSG00000140262 E012 19.2780660 0.0007219678 2.921410e-02 0.160425087 15 56919902 56919988 87 + 1.370 1.240 -0.452
ENSG00000140262 E013 18.7583144 0.0011253410 9.381680e-03 0.077114537 15 56921026 56921098 73 + 1.375 1.215 -0.561
ENSG00000140262 E014 0.2357071 0.0156653232 1.143831e-01   15 57001349 57001384 36 + 0.208 0.000 -13.794
ENSG00000140262 E015 0.2441377 0.0163769790 7.008291e-01   15 57063748 57063749 2 + 0.116 0.077 -0.655
ENSG00000140262 E016 19.2449838 0.0007324654 7.819428e-03 0.068073132 15 57063750 57063823 74 + 1.386 1.225 -0.563
ENSG00000140262 E017 1.8508393 0.0075479390 8.684501e-01 0.954837109 15 57072653 57072714 62 + 0.454 0.440 -0.070
ENSG00000140262 E018 21.0232331 0.0027810967 9.493932e-02 0.320589608 15 57091789 57091891 103 + 1.386 1.291 -0.333
ENSG00000140262 E019 0.0000000       15 57091892 57092023 132 +      
ENSG00000140262 E020 0.2537694 0.0160135382 4.641629e-01   15 57109258 57109317 60 + 0.000 0.143 12.215
ENSG00000140262 E021 0.0000000       15 57118350 57118433 84 +      
ENSG00000140262 E022 0.3726934 0.0166816713 9.711323e-01   15 57129783 57129972 190 + 0.116 0.143 0.345
ENSG00000140262 E023 0.0000000       15 57134316 57134500 185 +      
ENSG00000140262 E024 0.4801542 0.4555050904 3.293178e-01   15 57149954 57150025 72 + 0.283 0.077 -2.238
ENSG00000140262 E025 15.2968078 0.0081957283 6.196386e-01 0.835468804 15 57166402 57166466 65 + 1.214 1.189 -0.089
ENSG00000140262 E026 23.4208844 0.0056302650 4.250777e-01 0.704196049 15 57192158 57192293 136 + 1.397 1.359 -0.133
ENSG00000140262 E027 17.7735608 0.0008704318 8.078332e-01 0.929104442 15 57197773 57197825 53 + 1.260 1.259 -0.003
ENSG00000140262 E028 0.3707119 0.2353153003 1.000000e+00   15 57214079 57214396 318 + 0.116 0.143 0.346
ENSG00000140262 E029 0.1272623 0.0123494294 9.542608e-01   15 57219037 57219429 393 + 0.000 0.077 11.266
ENSG00000140262 E030 0.0000000       15 57219430 57219434 5 +      
ENSG00000140262 E031 0.1265070 0.0123003828 9.542744e-01   15 57219435 57219465 31 + 0.000 0.077 11.266
ENSG00000140262 E032 0.3709916 0.0166185060 9.713389e-01   15 57219466 57219590 125 + 0.116 0.143 0.345
ENSG00000140262 E033 29.1003797 0.0008659437 4.626093e-01 0.732989873 15 57231152 57231257 106 + 1.480 1.455 -0.085
ENSG00000140262 E034 36.7369412 0.0003899072 5.852051e-01 0.815753556 15 57232291 57232430 140 + 1.534 1.578 0.152
ENSG00000140262 E035 41.3045548 0.0003627080 2.603218e-01 0.552966430 15 57232712 57232856 145 + 1.634 1.598 -0.124
ENSG00000140262 E036 22.9691994 0.0006374181 9.391523e-01 0.982589514 15 57234043 57234107 65 + 1.358 1.370 0.041
ENSG00000140262 E037 24.9881219 0.0005669415 1.139284e-01 0.355467770 15 57243472 57243550 79 + 1.448 1.370 -0.269
ENSG00000140262 E038 0.2373413 0.0157175483 1.143597e-01   15 57243551 57243553 3 + 0.208 0.000 -13.793
ENSG00000140262 E039 0.0000000       15 57248016 57248040 25 +      
ENSG00000140262 E040 0.0000000       15 57248041 57248041 1 +      
ENSG00000140262 E041 0.0000000       15 57248042 57248081 40 +      
ENSG00000140262 E042 0.4992614 0.0152518914 6.117982e-01   15 57251169 57251349 181 + 0.116 0.200 0.930
ENSG00000140262 E043 25.8841305 0.0084410033 3.139965e-01 0.607117340 15 57251350 57251423 74 + 1.448 1.394 -0.184
ENSG00000140262 E044 0.1176306 0.0117508370 3.208446e-01   15 57252199 57252420 222 + 0.116 0.000 -12.859
ENSG00000140262 E045 0.4906064 0.0836080719 6.312176e-01   15 57252421 57252492 72 + 0.208 0.143 -0.655
ENSG00000140262 E046 45.6066947 0.0115657974 4.497100e-02 0.207304760 15 57253262 57253468 207 + 1.718 1.611 -0.366
ENSG00000140262 E047 32.4946326 0.0038607957 8.842691e-02 0.308527438 15 57262094 57262208 115 + 1.560 1.478 -0.281
ENSG00000140262 E048 43.0671645 0.0007331961 6.855097e-01 0.870099765 15 57263112 57263274 163 + 1.631 1.629 -0.008
ENSG00000140262 E049 14.4001808 0.0137390721 1.859941e-01 0.463901506 15 57273030 57273032 3 + 1.081 1.220 0.497
ENSG00000140262 E050 71.5411547 0.0002098334 9.019969e-01 0.968612760 15 57273033 57273262 230 + 1.832 1.854 0.073
ENSG00000140262 E051 0.1265070 0.0123003828 9.542744e-01   15 57281647 57281792 146 + 0.000 0.077 11.266
ENSG00000140262 E052 0.3717469 0.0165640576 9.707675e-01   15 57282183 57282442 260 + 0.116 0.143 0.345
ENSG00000140262 E053 0.1186381 0.0118485222 3.208086e-01   15 57282443 57282444 2 + 0.116 0.000 -12.858
ENSG00000140262 E054 25.9446751 0.0005731516 9.345277e-01 0.981081436 15 57282445 57282454 10 + 1.402 1.424 0.075
ENSG00000140262 E055 57.5357917 0.0003718314 3.266910e-01 0.619084023 15 57282455 57282598 144 + 1.716 1.773 0.194
ENSG00000140262 E056 828.2882332 0.0017466383 9.051796e-05 0.002189236 15 57286157 57289903 3747 + 2.865 2.925 0.202
ENSG00000140262 E057 2.7434048 0.0500362060 3.579372e-01 0.647448878 15 57290829 57291124 296 + 0.454 0.615 0.760
ENSG00000140262 E058 0.1271363 0.0123235951 9.542718e-01   15 57299226 57299281 56 + 0.000 0.077 11.266

Help

Please Click HERE to learn more details about the results from DEXseq.