ENSG00000140332

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000440567 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding protein_coding 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 1.4121850 0.0000000 1.478120 0.0000000 0.8757726 7.217347 0.05361667 0.000000 0.056875 0.056875 0.733083524 0.007422326 FALSE TRUE
ENST00000451782 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding protein_coding 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 5.1602730 1.5818173 6.390653 0.9142609 0.4961881 2.007544 0.27527500 0.206675 0.284525 0.077850 0.792589094 0.007422326 FALSE TRUE
ENST00000557919 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding nonsense_mediated_decay 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 1.9206903 0.1871947 2.584376 0.1871947 0.5995818 3.717695 0.08760000 0.030100 0.117050 0.086950 0.424006167 0.007422326 FALSE TRUE
ENST00000558939 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding protein_coding 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 0.9820523 1.8487777 0.000000 1.0677734 0.0000000 -7.538210 0.12364167 0.323425 0.000000 -0.323425 0.375118902 0.007422326 FALSE TRUE
ENST00000559608 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding retained_intron 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 4.5876195 1.2010072 6.217361 1.2010072 3.5960112 2.362413 0.19222500 0.123000 0.238575 0.115575 0.854201297 0.007422326   FALSE
ENST00000559826 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding retained_intron 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 2.1486410 0.0000000 3.539187 0.0000000 3.5391867 8.471345 0.06821667 0.000000 0.128825 0.128825 1.000000000 0.007422326 FALSE FALSE
ENST00000560525 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding nonsense_mediated_decay 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 0.1106851 0.3320553 0.000000 0.3320553 0.0000000 -5.096158 0.01819167 0.054575 0.000000 -0.054575 0.700686447 0.007422326 TRUE TRUE
ENST00000560589 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding protein_coding 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 0.3710932 1.1132797 0.000000 0.3720082 0.0000000 -6.811573 0.05587500 0.167625 0.000000 -0.167625 0.007422326 0.007422326 FALSE TRUE
ENST00000654081 ENSG00000140332 No_inf pgKDN_inf TLE3 protein_coding protein_coding_CDS_not_defined 18.91826 6.861377 23.85764 0.9851309 2.691635 1.796385 1.3158131 0.0000000 3.205362 0.0000000 1.2449989 8.328837 0.06718333 0.000000 0.156375 0.156375 0.061011121 0.007422326 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140332 E001 13.0920663 0.0089494186 0.450460646 0.72376150 15 70047790 70048274 485 - 1.102 1.172 0.250
ENSG00000140332 E002 22.6311029 0.0138408401 0.060537529 0.24695795 15 70048275 70048868 594 - 1.295 1.441 0.507
ENSG00000140332 E003 4.1858391 0.0037287656 0.005336122 0.05193042 15 70048869 70048975 107 - 0.548 0.889 1.414
ENSG00000140332 E004 2.0896225 0.0646766233 0.127912915 0.37905949 15 70048976 70048976 1 - 0.371 0.623 1.243
ENSG00000140332 E005 8.4731154 0.0017351981 0.742052838 0.89791856 15 70048977 70049090 114 - 0.943 0.979 0.134
ENSG00000140332 E006 37.7307610 0.0004865839 0.044019132 0.20505544 15 70049091 70049798 708 - 1.528 1.629 0.343
ENSG00000140332 E007 4.2386050 0.0035453335 0.817468582 0.93360879 15 70049799 70049800 2 - 0.689 0.721 0.134
ENSG00000140332 E008 4.2386050 0.0035453335 0.817468582 0.93360879 15 70049801 70049801 1 - 0.689 0.721 0.134
ENSG00000140332 E009 7.1469399 0.0256442442 0.861800425 0.95217634 15 70049802 70049835 34 - 0.880 0.909 0.109
ENSG00000140332 E010 20.3807426 0.0008164919 0.158990640 0.42616166 15 70049836 70050096 261 - 1.272 1.369 0.336
ENSG00000140332 E011 15.1830757 0.0117742456 0.519028546 0.77380523 15 70050097 70050204 108 - 1.205 1.150 -0.193
ENSG00000140332 E012 0.7158339 0.0135110564 0.398264177 0.68232212 15 70050205 70051390 1186 - 0.266 0.132 -1.249
ENSG00000140332 E013 11.4641832 0.0022476757 0.693894521 0.87489497 15 70051391 70051467 77 - 1.084 1.053 -0.114
ENSG00000140332 E014 0.3624961 0.0165538909 1.000000000   15 70051468 70051505 38 - 0.126 0.132 0.073
ENSG00000140332 E015 11.7215952 0.0011875611 0.921068692 0.97539601 15 70052374 70052524 151 - 1.084 1.079 -0.018
ENSG00000140332 E016 1.7424595 0.0083191453 0.003163258 0.03589462 15 70052525 70053173 649 - 0.224 0.658 2.395
ENSG00000140332 E017 0.2543986 0.0160052453 0.075943672   15 70053174 70053226 53 - 0.000 0.233 12.558
ENSG00000140332 E018 9.6543044 0.0025540845 0.641718246 0.84794159 15 70053227 70053374 148 - 1.019 0.979 -0.150
ENSG00000140332 E019 0.1265070 0.0122988900 0.242421557   15 70053375 70054344 970 - 0.000 0.132 11.636
ENSG00000140332 E020 0.0000000       15 70054345 70054437 93 -      
ENSG00000140332 E021 12.4865969 0.0150516961 0.392875211 0.67789144 15 70054438 70054680 243 - 1.078 1.161 0.299
ENSG00000140332 E022 2.9034229 0.0045927443 0.925320438 0.97749941 15 70054681 70054685 5 - 0.568 0.584 0.073
ENSG00000140332 E023 0.8606516 0.1092475146 0.205366687 0.48860765 15 70054686 70055048 363 - 0.178 0.384 1.488
ENSG00000140332 E024 13.7555939 0.0010376819 0.546907792 0.79254460 15 70055049 70055296 248 - 1.161 1.116 -0.162
ENSG00000140332 E025 4.5583572 0.0033088110 0.121877568 0.36939510 15 70055297 70055298 2 - 0.783 0.584 -0.834
ENSG00000140332 E026 0.8496743 0.0155803106 0.569238895 0.80627638 15 70055299 70056297 999 - 0.224 0.315 0.658
ENSG00000140332 E027 9.1126547 0.0020017522 0.013771835 0.09893049 15 70056298 70056374 77 - 1.053 0.801 -0.951
ENSG00000140332 E028 2.2956244 0.0065141449 0.935808100 0.98160543 15 70057459 70057473 15 - 0.504 0.496 -0.043
ENSG00000140332 E029 7.8297274 0.0017236165 0.408467782 0.69076957 15 70057474 70057519 46 - 0.951 0.869 -0.312
ENSG00000140332 E030 12.7304310 0.0013336095 0.044804574 0.20699759 15 70057520 70057658 139 - 1.166 0.995 -0.623
ENSG00000140332 E031 0.9884858 0.0126553607 0.085289832 0.30205672 15 70057659 70058090 432 - 0.178 0.443 1.810
ENSG00000140332 E032 0.0000000       15 70058091 70058149 59 -      
ENSG00000140332 E033 0.4981279 0.0157903293 0.084990188   15 70058150 70058158 9 - 0.068 0.315 2.658
ENSG00000140332 E034 4.3188135 0.0033540188 0.179099115 0.45413877 15 70058159 70058185 27 - 0.758 0.584 -0.735
ENSG00000140332 E035 11.2943774 0.0013808052 0.054035169 0.23135134 15 70058186 70058291 106 - 1.119 0.945 -0.638
ENSG00000140332 E036 0.0000000       15 70058292 70058662 371 -      
ENSG00000140332 E037 17.1285505 0.0102578380 0.329009976 0.62147838 15 70058663 70058815 153 - 1.261 1.182 -0.278
ENSG00000140332 E038 7.5983364 0.0019862952 0.509046931 0.76708984 15 70059410 70059460 51 - 0.934 0.869 -0.249
ENSG00000140332 E039 9.9203325 0.0014727797 0.923646905 0.97672631 15 70060530 70060649 120 - 1.012 1.025 0.046
ENSG00000140332 E040 3.6529583 0.0045188903 0.217435936 0.50387513 15 70064454 70064470 17 - 0.588 0.749 0.686
ENSG00000140332 E041 6.0878022 0.0022648041 0.158781634 0.42584429 15 70066014 70066122 109 - 0.770 0.927 0.607
ENSG00000140332 E042 2.7908206 0.0204084014 0.816576748 0.93317619 15 70066123 70066143 21 - 0.548 0.584 0.166
ENSG00000140332 E043 4.0617712 0.0035809319 0.018700285 0.12136958 15 70066144 70066215 72 - 0.770 0.443 -1.463
ENSG00000140332 E044 2.2598719 0.0061497518 0.025825903 0.14848478 15 70066216 70066218 3 - 0.588 0.233 -2.015
ENSG00000140332 E045 0.1268540 0.0124143764 0.242338743   15 70066618 70066939 322 - 0.000 0.132 11.636
ENSG00000140332 E046 0.0000000       15 70074503 70074532 30 -      
ENSG00000140332 E047 4.8928463 0.0396457570 0.052841389 0.22846613 15 70074533 70074607 75 - 0.828 0.542 -1.207
ENSG00000140332 E048 5.2693263 0.0482861838 0.260466782 0.55307465 15 70076096 70076158 63 - 0.828 0.658 -0.692
ENSG00000140332 E049 5.0570634 0.0072705440 0.598324882 0.82388578 15 70094532 70094576 45 - 0.783 0.721 -0.249
ENSG00000140332 E050 0.0000000       15 70094726 70094785 60 -      
ENSG00000140332 E051 0.1271363 0.0123346993 0.242439812   15 70095390 70095577 188 - 0.000 0.132 11.636
ENSG00000140332 E052 5.8228290 0.0027828149 0.461601602 0.73223335 15 70095578 70095641 64 - 0.783 0.869 0.336
ENSG00000140332 E053 0.1268540 0.0124143764 0.242338743   15 70095642 70095950 309 - 0.000 0.132 11.636
ENSG00000140332 E054 5.3258035 0.0029103423 0.815456268 0.93251545 15 70096161 70096261 101 - 0.770 0.801 0.122
ENSG00000140332 E055 0.1176306 0.0117888739 1.000000000   15 70096262 70096676 415 - 0.068 0.000 -10.851
ENSG00000140332 E056 0.0000000       15 70096677 70096752 76 -      
ENSG00000140332 E057 14.0721583 0.0010131209 0.068520773 0.26423562 15 70096775 70097404 630 - 1.200 1.053 -0.529
ENSG00000140332 E058 2.0504387 0.0089894474 0.790373003 0.91966838 15 70097405 70097439 35 - 0.481 0.443 -0.190
ENSG00000140332 E059 3.9855523 0.0037567554 0.793836421 0.92138041 15 70097440 70097558 119 - 0.689 0.658 -0.129
ENSG00000140332 E060 2.2957921 0.0087169889 0.940675416 0.98318646 15 70097559 70097657 99 - 0.504 0.496 -0.043
ENSG00000140332 E061 2.6695101 0.0059250913 0.699716276 0.87760833 15 70097658 70098176 519 - 0.527 0.584 0.265

Help

Please Click HERE to learn more details about the results from DEXseq.