ENSG00000140474

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000440863 ENSG00000140474 No_inf pgKDN_inf ULK3 protein_coding protein_coding 42.0711 56.07629 36.04267 1.760505 2.339473 -0.637542 2.525694 0.000000 7.577083 0.0000000 2.9652470 9.5674014 0.07467500 0.000000 0.224025 0.224025 0.006051677 0.006051677 FALSE TRUE
ENST00000567472 ENSG00000140474 No_inf pgKDN_inf ULK3 protein_coding retained_intron 42.0711 56.07629 36.04267 1.760505 2.339473 -0.637542 11.303588 14.791432 10.345461 3.2283732 1.3694254 -0.5153451 0.26292500 0.259250 0.287800 0.028550 0.899690107 0.006051677 FALSE TRUE
ENST00000570276 ENSG00000140474 No_inf pgKDN_inf ULK3 protein_coding retained_intron 42.0711 56.07629 36.04267 1.760505 2.339473 -0.637542 8.649107 15.944579 4.291141 1.4688354 0.5085812 -1.8911792 0.19145000 0.282925 0.120675 -0.162250 0.024617518 0.006051677 FALSE TRUE
MSTRG.9925.12 ENSG00000140474 No_inf pgKDN_inf ULK3 protein_coding   42.0711 56.07629 36.04267 1.760505 2.339473 -0.637542 8.456237 8.420906 5.977767 1.8652663 3.4558347 -0.4936695 0.21487500 0.153750 0.156850 0.003100 0.819738759 0.006051677 FALSE TRUE
MSTRG.9925.8 ENSG00000140474 No_inf pgKDN_inf ULK3 protein_coding   42.0711 56.07629 36.04267 1.760505 2.339473 -0.637542 4.410053 7.911991 1.816141 0.9465109 0.3657740 -2.1170650 0.09824167 0.141625 0.050100 -0.091525 0.105397921 0.006051677 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000140474 E001 0.0000000       15 74836118 74836121 4 -      
ENSG00000140474 E002 0.1271363 0.0123567648 1.0000000000   15 74836122 74836131 10 - 0.000 0.073 8.667
ENSG00000140474 E003 0.1271363 0.0123567648 1.0000000000   15 74836132 74836138 7 - 0.000 0.073 11.197
ENSG00000140474 E004 0.6249819 0.0149902566 0.4503063438 0.723726752 15 74836139 74836153 15 - 0.122 0.240 1.180
ENSG00000140474 E005 1.1137031 0.0117897239 0.8623971830 0.952520523 15 74836154 74836156 3 - 0.296 0.323 0.180
ENSG00000140474 E006 2.2386408 0.0073195810 0.4563468790 0.728722263 15 74836157 74836165 9 - 0.419 0.531 0.558
ENSG00000140474 E007 95.5858585 0.0001872879 0.0609647515 0.247888077 15 74836166 74836632 467 - 1.924 1.982 0.197
ENSG00000140474 E008 55.6704220 0.0005951313 0.9442130921 0.984572234 15 74836633 74836804 172 - 1.730 1.733 0.010
ENSG00000140474 E009 40.0249838 0.0003759209 0.4969005618 0.757742448 15 74836805 74836892 88 - 1.613 1.580 -0.112
ENSG00000140474 E010 40.9691691 0.0004257479 0.8436964227 0.944147477 15 74836893 74836963 71 - 1.595 1.605 0.032
ENSG00000140474 E011 25.6874031 0.0121417717 0.3401240779 0.631872235 15 74836964 74836972 9 - 1.358 1.428 0.242
ENSG00000140474 E012 67.2097114 0.0017259101 0.8316516799 0.939239084 15 74836973 74837198 226 - 1.807 1.815 0.027
ENSG00000140474 E013 15.4845695 0.0010304814 0.6808916180 0.868167148 15 74837199 74837212 14 - 1.176 1.207 0.111
ENSG00000140474 E014 20.7623049 0.0090788126 0.0976708315 0.325754661 15 74837213 74837244 32 - 1.229 1.357 0.447
ENSG00000140474 E015 30.1826927 0.0005082866 0.0595021606 0.244663065 15 74837369 74837435 67 - 1.399 1.507 0.371
ENSG00000140474 E016 15.6974569 0.0011049305 0.8419364637 0.943293675 15 74837751 74837756 6 - 1.212 1.197 -0.053
ENSG00000140474 E017 17.1327062 0.0126852343 0.2951404942 0.588432103 15 74837757 74837798 42 - 1.291 1.207 -0.296
ENSG00000140474 E018 2.6142233 0.0058479675 0.4654171234 0.734464907 15 74837799 74837956 158 - 0.470 0.576 0.502
ENSG00000140474 E019 11.3675861 0.0012168004 0.7109129568 0.883119041 15 74838152 74838173 22 - 1.093 1.061 -0.117
ENSG00000140474 E020 9.9777091 0.0013810917 0.2845034487 0.578205178 15 74838174 74838192 19 - 1.081 0.985 -0.353
ENSG00000140474 E021 18.7633760 0.0008887292 0.4008529437 0.684118946 15 74838266 74838344 79 - 1.312 1.254 -0.204
ENSG00000140474 E022 15.8544804 0.0021568458 0.6814340627 0.868278095 15 74838440 74838504 65 - 1.185 1.217 0.113
ENSG00000140474 E023 0.6155752 0.0181320423 0.8586648883 0.950734579 15 74838505 74838512 8 - 0.218 0.191 -0.235
ENSG00000140474 E024 21.6695052 0.0100390495 0.1590437509 0.426244853 15 74838643 74838745 103 - 1.399 1.296 -0.358
ENSG00000140474 E025 14.7276977 0.0010548283 0.0191029911 0.123271204 15 74839010 74839050 41 - 1.284 1.107 -0.628
ENSG00000140474 E026 4.3829363 0.0053111296 0.0403041540 0.194674127 15 74839051 74839267 217 - 0.515 0.789 1.180
ENSG00000140474 E027 19.6606477 0.0008864381 0.0222103420 0.135530912 15 74839268 74839373 106 - 1.388 1.236 -0.531
ENSG00000140474 E028 1.1253424 0.0129128883 0.3713409999 0.659339501 15 74839374 74839413 40 - 0.218 0.360 0.987
ENSG00000140474 E029 0.3727544 0.0167417075 1.0000000000   15 74839523 74839557 35 - 0.122 0.136 0.180
ENSG00000140474 E030 24.3651885 0.0006298883 0.0245268988 0.143786278 15 74839558 74839713 156 - 1.467 1.331 -0.469
ENSG00000140474 E031 7.3075026 0.0019825430 0.9266850722 0.978062129 15 74840234 74840241 8 - 0.894 0.903 0.035
ENSG00000140474 E032 8.5640763 0.0019779740 0.4603943410 0.731860329 15 74840242 74840264 23 - 0.911 0.985 0.275
ENSG00000140474 E033 10.9919637 0.0031644796 0.6970673293 0.876354406 15 74840265 74840296 32 - 1.081 1.047 -0.126
ENSG00000140474 E034 10.4527670 0.0014854905 0.1655827248 0.435338729 15 74840297 74840316 20 - 1.115 0.993 -0.445
ENSG00000140474 E035 5.5944045 0.0026051560 0.3061982357 0.599321431 15 74840317 74840318 2 - 0.718 0.838 0.479
ENSG00000140474 E036 18.2472834 0.0019364971 0.0001241011 0.002831277 15 74840319 74840497 179 - 1.045 1.346 1.071
ENSG00000140474 E037 19.2791802 0.0051734384 0.7905483285 0.919686877 15 74840498 74840586 89 - 1.298 1.280 -0.064
ENSG00000140474 E038 11.9031037 0.0016029442 0.5656557748 0.804389447 15 74840587 74840594 8 - 1.057 1.107 0.180
ENSG00000140474 E039 14.4060197 0.0010449144 0.2471769096 0.537761378 15 74840595 74840614 20 - 1.104 1.197 0.332
ENSG00000140474 E040 15.1408030 0.0010868131 0.3336552689 0.625659408 15 74840615 74840641 27 - 1.136 1.212 0.269
ENSG00000140474 E041 15.9365921 0.0023551883 0.6726263728 0.864445963 15 74841405 74841448 44 - 1.229 1.197 -0.113
ENSG00000140474 E042 19.1204777 0.0034870657 0.3437677588 0.635088385 15 74841449 74841493 45 - 1.326 1.258 -0.235
ENSG00000140474 E043 14.2756962 0.0057017158 0.1060683621 0.341027827 15 74841494 74841505 12 - 1.245 1.113 -0.470
ENSG00000140474 E044 13.5331118 0.0017726073 0.0758291982 0.281374061 15 74841506 74841509 4 - 1.229 1.088 -0.504
ENSG00000140474 E045 21.2106208 0.0052464218 0.2077819305 0.491470513 15 74842075 74842118 44 - 1.382 1.292 -0.312
ENSG00000140474 E046 23.7070902 0.0022731383 0.3496156173 0.639931854 15 74842119 74842195 77 - 1.410 1.350 -0.210
ENSG00000140474 E047 2.6232929 0.0304395099 0.2527413304 0.544117961 15 74842196 74842279 84 - 0.419 0.596 0.858
ENSG00000140474 E048 31.5024785 0.0104161125 0.4994951470 0.759722822 15 74842280 74842417 138 - 1.521 1.473 -0.165
ENSG00000140474 E049 6.8043121 0.0022019094 0.9747490001 0.995411363 15 74842418 74842420 3 - 0.875 0.872 -0.013
ENSG00000140474 E050 2.0070926 0.1606770685 0.2011532467 0.483380824 15 74842421 74842449 29 - 0.296 0.531 1.294
ENSG00000140474 E051 1.8796093 0.0259326552 0.1861550461 0.463995337 15 74842450 74842534 85 - 0.296 0.507 1.180
ENSG00000140474 E052 1.4877474 0.0089116342 0.8398426249 0.942588222 15 74842535 74842538 4 - 0.362 0.393 0.180
ENSG00000140474 E053 2.5871560 0.0054507587 0.5332893136 0.783781395 15 74842539 74842545 7 - 0.594 0.507 -0.405
ENSG00000140474 E054 4.9828909 0.0029589394 0.2484666718 0.539332444 15 74842546 74842650 105 - 0.661 0.802 0.578
ENSG00000140474 E055 1.2527996 0.0104974719 0.2695773315 0.563270842 15 74842651 74842674 24 - 0.218 0.393 1.180
ENSG00000140474 E056 4.3574726 0.0107773035 0.3555250455 0.645305493 15 74842675 74843003 329 - 0.629 0.749 0.502
ENSG00000140474 E057 10.7698405 0.0133324724 0.7802227015 0.915266043 15 74843004 74843346 343 - 1.032 1.061 0.106

Help

Please Click HERE to learn more details about the results from DEXseq.